Zobrazeno 1 - 10
of 377
pro vyhledávání: '"J. A. Hagen"'
Autor:
T. Blikman, W. Rienstra, T. M. van Raaij, A. J. ten Hagen, B. Dijkstra, W. P. Zijlstra, S. K. Bulstra, M. Stevens, I. van den Akker-Scheek
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Some osteoarthritis (OA) patients experience inadequate pain relief from analgesics like acetaminophen and nonsteroidal anti-inflammatory drugs. This could be the result of experienced non-nociceptive centralized pain. Placebo-con
Externí odkaz:
https://doaj.org/article/ea5e8702ea2741d1a67547fd5dff43a6
Publikováno v:
European Psychiatry, Vol 66, Pp S458-S459 (2023)
Introduction Internet-based cognitive behavioral therapy (iCBT) programs have been widely acknowledged as effective resources to treat common mental health disorders (CMDs) like depression or anxiety. However, real-world uptake rates remain low, whic
Externí odkaz:
https://doaj.org/article/e516adf4fe2749cd81325a66d1767f19
Publikováno v:
European Psychiatry, Vol 65, Pp S292-S292 (2022)
Introduction Since fall 2020, electronic mental health services (eMHSs) like apps can be prescribed by physicians and psychotherapists in Germany. However, future healthcare providers such as medical and psychology students remain reluctant to adopt
Externí odkaz:
https://doaj.org/article/ecc6039ef4354cd6928119201418b1c2
Autor:
Wim J. H. Hagen
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Transmission electron cryo-microscopy (cryo-EM) allows for obtaining 3D structural information by imaging macromolecules embedded in thin layers of amorphous ice. To obtain high-resolution structural information, samples need to be thin to minimize i
Externí odkaz:
https://doaj.org/article/3f97d01ceb044c54bbfe365be0552c63
Autor:
Brice Noël, C. L. Jakobs, W. J. J. van Pelt, S. Lhermitte, B. Wouters, J. Kohler, J. O. Hagen, B. Luks, C. H. Reijmer, W. J. van de Berg, M. R. van den Broeke
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Svalbard glaciers are among the lowest ice masses in the Arctic, with a peak in glacier area below 450 m elevation. Using a high-resolution climate model, here the authors show that a modest warming in the mid-1980s propagated meltwater runoff above
Externí odkaz:
https://doaj.org/article/1e271ff961d040389b45c650d39fac9a
Autor:
Beata Turoňová, Wim J. H. Hagen, Martin Obr, Shyamal Mosalaganti, J. Wouter Beugelink, Christian E. Zimmerli, Hans-Georg Kräusslich, Martin Beck
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Here the authors systematically benchmark cryo-electron tomography acquisition schemes to optimize the attainable resolution for subtomogram averaging, and find that dose-symmetric acquisition with even angular sampling provides a better outcome than
Externí odkaz:
https://doaj.org/article/dc1b4bdb76a14aba9eff82a68c42333e
Autor:
Arjen J. Jakobi, Stefan T. Huber, Simon A. Mortensen, Sebastian W. Schultz, Anthimi Palara, Tanja Kuhm, Birendra Kumar Shrestha, Trond Lamark, Wim J. H. Hagen, Matthias Wilmanns, Terje Johansen, Andreas Brech, Carsten Sachse
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
PB1-mediated oligomerization of p62/SQSTM1 is essential for its function as a selective autophagy receptor. Here the authors present the cryo-EM structures of human and Arabidopsis PB1 domain helical assemblies and find that a conserved double argini
Externí odkaz:
https://doaj.org/article/3681d17d79a54c59a34880abff981baa
Autor:
W. van Pelt, V. Pohjola, R. Pettersson, S. Marchenko, J. Kohler, B. Luks, J. O. Hagen, T. V. Schuler, T. Dunse, B. Noël, C. Reijmer
Publikováno v:
The Cryosphere, Vol 13, Pp 2259-2280 (2019)
The climate in Svalbard is undergoing amplified change compared to the global mean. This has major implications for runoff from glaciers and seasonal snow on land. We use a coupled energy balance–subsurface model, forced with downscaled regional cl
Externí odkaz:
https://doaj.org/article/d397737ac10946f49aff67cac3d49cd3
Publikováno v:
The Cryosphere, Vol 11, Iss 1, Pp 191-215 (2017)
Estimating the long-term mass balance of the high-Arctic Svalbard archipelago is difficult due to the incomplete geodetic and direct glaciological measurements, both in space and time. To close these gaps, we use a coupled surface energy balance and
Externí odkaz:
https://doaj.org/article/2456f39dd52f42d5921dd64b0c9ce0de
Publikováno v:
The Cryosphere, Vol 9, Iss 1, Pp 197-215 (2015)
Mass loss from glaciers and ice sheets currently accounts for two-thirds of the observed global sea-level rise and has accelerated since the 1990s, coincident with strong atmospheric warming in the polar regions. Here we present continuous GPS measur
Externí odkaz:
https://doaj.org/article/b9db90db649046478e06504d81296b8e