Zobrazeno 1 - 10
of 188
pro vyhledávání: '"J. A. Grootegoed"'
Autor:
Leen J. Blok, Riccardo Fodde, Curt W. Burger, J. Anton Grootegoed, J. Julie Kim, Patricia C. Ewing, Helena C. van Doorn, Jos Veldscholte, Patrick Franken, Helenius J. Kloosterboer, Eline E. Hanekamp, Payman Hanifi-Moghaddam, Yongyi Wang
Purpose. Wnt signaling regulates the fine balance between stemness and differentiation. Here, the role of Wnt signaling to maintain the balance between estrogen-induced proliferation and progesterone-induced differentiation during the menstrual cycle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6396a9001a13b1a9a88a1d525adcfac0
https://doi.org/10.1158/1078-0432.c.6517768.v1
https://doi.org/10.1158/1078-0432.c.6517768.v1
Autor:
Leen J. Blok, Riccardo Fodde, Curt W. Burger, J. Anton Grootegoed, J. Julie Kim, Patricia C. Ewing, Helena C. van Doorn, Jos Veldscholte, Patrick Franken, Helenius J. Kloosterboer, Eline E. Hanekamp, Payman Hanifi-Moghaddam, Yongyi Wang
Supplementary Data from Progesterone Inhibition of Wnt/β-Catenin Signaling in Normal Endometrium and Endometrial Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5eed5801f29dcdf0225e40030daf07a
https://doi.org/10.1158/1078-0432.22440439
https://doi.org/10.1158/1078-0432.22440439
Autor:
Tahsin Stefan Barakat, Mehrnaz Ghazvini, Bas de Hoon, Tracy Li, Bert Eussen, Hannie Douben, Reinier van der Linden, Nathalie van der Stap, Marjan Boter, Joop S. Laven, Robert-Jan Galjaard, J. Anton Grootegoed, Annelies de Klein, Joost Gribnau
Publikováno v:
Stem Cell Reports, Vol 4, Iss 2, Pp 199-208 (2015)
In placental mammals, balanced expression of X-linked genes is accomplished by X chromosome inactivation (XCI) in female cells. In humans, random XCI is initiated early during embryonic development. To investigate whether reprogramming of female huma
Externí odkaz:
https://doaj.org/article/65e2748f7a6c4655a09a3d0701890f98
Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse.
Autor:
Federica Federici, Aristea Magaraki, Evelyne Wassenaar, Catherina J H van Veen-Buurman, Christine van de Werken, Esther B Baart, Joop S E Laven, J Anton Grootegoed, Joost Gribnau, Willy M Baarends
Publikováno v:
PLoS Genetics, Vol 12, Iss 10, p e1006358 (2016)
In mouse female preimplantation embryos, the paternal X chromosome (Xp) is silenced by imprinted X chromosome inactivation (iXCI). This requires production of the noncoding Xist RNA in cis, from the Xp. The Xist locus on the maternally inherited X ch
Externí odkaz:
https://doaj.org/article/9d08fb3963e04fdaa5e1f586a9987f9d
Autor:
Fabrizia Carofiglio, Akiko Inagaki, Sandra de Vries, Evelyne Wassenaar, Sam Schoenmakers, Christie Vermeulen, Wiggert A van Cappellen, Esther Sleddens-Linkels, J Anton Grootegoed, Hein P J Te Riele, Bernard de Massy, Willy M Baarends
Publikováno v:
PLoS Genetics, Vol 9, Iss 6, p e1003538 (2013)
In mammalian meiotic prophase, the initial steps in repair of SPO11-induced DNA double-strand breaks (DSBs) are required to obtain stable homologous chromosome pairing and synapsis. The X and Y chromosomes pair and synapse only in the short pseudo-au
Externí odkaz:
https://doaj.org/article/a7d625c6f441479a9341157e8a477ac9
Autor:
Yongyi Wang, Andrea Sacchetti, Matthijs R van Dijk, Marten van der Zee, Paul H van der Horst, Rosalie Joosten, Curt W Burger, J Anton Grootegoed, Leen J Blok, Riccardo Fodde
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40691 (2012)
In fertile women, the endometrium undergoes regular cycles of tissue build-up and regression. It is likely that uterine stem cells are involved in this remarkable turn over. The main goal of our current investigations was to identify slow-cycling (qu
Externí odkaz:
https://doaj.org/article/1ace66538422437598500c3dd51b77f1
Autor:
Akiko Inagaki, Esther Sleddens-Linkels, Wiggert A van Cappellen, Richard G Hibbert, Titia K Sixma, Jan H J Hoeijmakers, J Anton Grootegoed, Willy M Baarends
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23155 (2011)
RAD18 is an ubiquitin ligase involved in replicative damage bypass and DNA double-strand break (DSB) repair processes. We found that RPA is required for the dynamic pattern of RAD18 localization during the cell cycle, and for accumulation of RAD18 at
Externí odkaz:
https://doaj.org/article/510de189dc134958a33ecdd4c447051a
Autor:
Tahsin Stefan Barakat, Nilhan Gunhanlar, Cristina Gontan Pardo, Eskeatnaf Mulugeta Achame, Mehrnaz Ghazvini, Ruben Boers, Annegien Kenter, Eveline Rentmeester, J Anton Grootegoed, Joost Gribnau
Publikováno v:
PLoS Genetics, Vol 7, Iss 1, p e1002001 (2011)
In somatic cells of female placental mammals, one of the two X chromosomes is transcriptionally silenced to accomplish an equal dose of X-encoded gene products in males and females. Initiation of random X chromosome inactivation (XCI) is thought to b
Externí odkaz:
https://doaj.org/article/84f0bc74bcff4676adf5012c4a793f6d
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15598 (2010)
Chimpanzees and humans are genetically very similar, with the striking exception of their Y chromosomes, which have diverged tremendously. The male-specific region (MSY), representing the greater part of the Y chromosome, is inherited from father to
Externí odkaz:
https://doaj.org/article/9883c58b2e724ea4a53cabaa2177f23f
Autor:
Sam Schoenmakers, Evelyne Wassenaar, Jos W Hoogerbrugge, Joop S E Laven, J Anton Grootegoed, Willy M Baarends
Publikováno v:
PLoS Genetics, Vol 5, Iss 5, p e1000466 (2009)
During meiotic prophase in male mammals, the heterologous X and Y chromosomes remain largely unsynapsed, and meiotic sex chromosome inactivation (MSCI) leads to formation of the transcriptionally silenced XY body. In birds, the heterogametic sex is f
Externí odkaz:
https://doaj.org/article/032f8631883c433f8091d66823b2e37b