Zobrazeno 1 - 10
of 96
pro vyhledávání: '"J. A. Flora"'
Autor:
Archna Panghal, S. J. S. Flora
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-20 (2024)
Abstract Multiple sclerosis (MS) is a neuroimmunological disorder which causes axonal damage, demyelination and paralysis. Although numerous therapeutics have been developed for the effective treatment of MS and a few have been approved in recent dec
Externí odkaz:
https://doaj.org/article/4d105084380f4d969637144abc5c7c21
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Breast cancer is one of the most diagnosed solid cancers globally. Extensive research has been going on for decades to meet the challenges of treating solid tumors with selective compounds. This article aims to summarize the therapeutic agents which
Externí odkaz:
https://doaj.org/article/e608b37a0b154f6f9256b796752e12b2
Autor:
Megha Mathur, Neha Rawat, Tanushree Saxena, Renu Khandelwal, Neha Jain, Mukesh K. Sharma, Medicherla K. Mohan, Pradeep Bhatnagar, Swaran J. S. Flora, Pallavi Kaushik
Publikováno v:
Toxics, Vol 11, Iss 11, p 945 (2023)
Fluoride (F) and arsenic (As) are two major contaminants of water and soil systems around the globe, causing potential toxicity to humans, plants, animals, and microbes. These contaminated soil systems can be restored by microorganisms that can toler
Externí odkaz:
https://doaj.org/article/2fd227a2ba644bc3990422a4aa514b79
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Monoisoamyl 2,3-dimercaptosuccinic acid (MiADMSA), a lipophilic chelator has been evaluated for its potential use as an antidote in arsenic poisoning. The pharmacokinetics and pharmacodynamics properties of a drug could be understood via stu
Externí odkaz:
https://doaj.org/article/f39c08499f5349fd9e99a2e7121b7f63
Publikováno v:
ACS Omega, Vol 6, Iss 1, Pp 559-568 (2020)
Externí odkaz:
https://doaj.org/article/668d464b15034217a9363d10e8ea1289
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 6, Iss 1, Pp 1-10 (2020)
Abstract Background A simple, rapid and accurate reverse phase RP-HPLC method for the validation of antitubercular drug bedaquiline fumarate (BQF) was developed. The stability and forced degradation behaviour of bedaquiline fumarate (BQF) in official
Externí odkaz:
https://doaj.org/article/ea9d1b9a09d444898929b83f89d10f4e
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
We evaluated the neuro-, immuno-, and male reproductive toxicity of zinc oxide nanoparticles (ZnO NPs) alone and in combination with lead acetate. We also studied the therapeutic role of α-lipoic acid postexposure. Lead (10 mg/kg, body weight), ZnO
Externí odkaz:
https://doaj.org/article/2c2df87555c24492b333a333b27fab68
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Central nervous system (CNS) disorders especially neurodegenerative disorders are the major challenge for public health and demand the great attention of researchers to protect people against them. In past few decades, different treatment strategies
Externí odkaz:
https://doaj.org/article/6023432d597c46ba85a6b55e191a7e18
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Alzheimer’s disease (AD) is the age linked neurodegenerative disorder with no disease modifying therapy currently available. The available therapy only offers short term symptomatic relief. Several hypotheses have been suggested for the pathogenesi
Externí odkaz:
https://doaj.org/article/028f251593a44960af583fa6b2605a63
Publikováno v:
Chemical research in toxicology. 35(10)
Arsenic, a metalloid, is known to cause deleterious effects in various body organs, particularly the liver, urinary bladder, and brain, and these effects are primarily mediated through oxidative stress. Chelation therapy has been considered one of th