Zobrazeno 1 - 10
of 32
pro vyhledávání: '"J. A. Fites"'
Autor:
Tonie E. Rocke, Brock Kingstad-Bakke, Marcel Wüthrich, Ben Stading, Rachel C. Abbott, Marcos Isidoro-Ayza, Hannah E. Dobson, Lucas dos Santos Dias, Kevin Galles, Julia S. Lankton, Elizabeth A. Falendysz, Jeffrey M. Lorch, J. Scott Fites, Jaime Lopera-Madrid, J. Paul White, Bruce Klein, Jorge E. Osorio
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract White-nose syndrome (WNS) caused by the fungus, Pseudogymnoascus destructans (Pd) has killed millions of North American hibernating bats. Currently, methods to prevent the disease are limited. We conducted two trials to assess potential WNS
Externí odkaz:
https://doaj.org/article/6d8f3b480a084707931474796061c861
Autor:
Lucas Dos Santos Dias, Hannah E Dobson, Brock Kingstad Bakke, Gregory C Kujoth, Junfeng Huang, Elaine M Kohn, Cleison Ledesma Taira, Huafeng Wang, Nitin T Supekar, J Scott Fites, Daisy Gates, Christina L Gomez, Charles A Specht, Stuart M Levitz, Parastoo Azadi, Lingjun Li, Marulasiddappa Suresh, Bruce S Klein, Marcel Wüthrich
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009324 (2021)
The development of safe subunit vaccines requires adjuvants that augment immunogenicity of non-replicating protein-based antigens. Current vaccines against infectious diseases preferentially induce protective antibodies driven by adjuvants such as al
Externí odkaz:
https://doaj.org/article/fc7f3feb47ae4cc8a5f6edd4c6048362
Autor:
Paige E. Negoro, Shuying Xu, Zeina Dagher, Alex Hopke, Jennifer L. Reedy, Michael B. Feldman, Nida S. Khan, Adam L. Viens, Natalie J. Alexander, Natalie J. Atallah, Allison K. Scherer, Richard A. Dutko, Jane Jeffery, John F. Kernien, J. Scott Fites, Jeniel E. Nett, Bruce S. Klein, Jatin M. Vyas, Daniel Irimia, David B. Sykes, Michael K. Mansour
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Invasive fungal infections constitute a lethal threat, with patient mortality as high as 90%. The incidence of invasive fungal infections is increasing, especially in the setting of patients receiving immunomodulatory agents, chemotherapy, o
Externí odkaz:
https://doaj.org/article/8ea9d37e9ee144ada176ccd4590e9d2d
Autor:
Richard M. Merkhofer, Mary B. O’Neill, Donny Xiong, Nydiaris Hernandez-Santos, Hannah Dobson, J. Scott Fites, Abigail C. Shockey, Marcel Wuethrich, Caitlin S. Pepperell, Bruce S. Klein
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Genetic differences are hypothesized to underlie ethnic disparities in incidence rates of the endemic systemic mycoses, including blastomycosis. Individuals of Hmong ancestry display elevated risk for this serious fungal infection. Here, we
Externí odkaz:
https://doaj.org/article/91eb12aeeb194bb5b05e852023c0da39
Autor:
Xuequn Xu, Ginger M. Pocock, Akshat Sharma, Stephen L. Peery, J. Scott Fites, Laura Felley, Robert Zarnowski, Douglas Stewart, Erwin Berthier, Bruce S. Klein, Nathan M. Sherer, Jenny E. Gumperz
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3273-3285 (2016)
Invariant natural killer T (iNKT) cells are innate T lymphocytes that promote host defense against a variety of microbial pathogens. Whether microbial ligands are required for their protective effects remains unclear. Here, we show that iNKT cells st
Externí odkaz:
https://doaj.org/article/7668caf5e8ed4cfb9ef8d83b5ddf0ce2
Autor:
J Scott Fites, Michael Gui, John F Kernien, Paige Negoro, Zeina Dagher, David B Sykes, Jeniel E Nett, Michael K Mansour, Bruce S Klein
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1007073 (2018)
Neutrophils are classically defined as terminally differentiated, short-lived cells; however, neutrophils can be long-lived with phenotypic plasticity. During inflammation, a subset of neutrophils transdifferentiate into a population called neutrophi
Externí odkaz:
https://doaj.org/article/8c19581c703a430a8d5962c8363b744a
Autor:
Som Gowda Nanjappa, Andrew J McDermott, J Scott Fites, Kevin Galles, Marcel Wüthrich, George S Deepe, Bruce S Klein
Publikováno v:
PLoS Pathogens, Vol 13, Iss 5, p e1006356 (2017)
Our understanding of persistence and plasticity of IL-17A+ memory T cells is clouded by conflicting results in models analyzing T helper 17 cells. We studied memory IL-17A+ CD8+ T-cell (Tc17) homeostasis, persistence and plasticity during fungal vacc
Externí odkaz:
https://doaj.org/article/acf69b2d733948e596d520b9ceb8e3e7
Autor:
Hannah E. Dobson, Brock Kingstad Bakke, Bruce S. Klein, Stuart M. Levitz, Nitin T. Supekar, Lucas Dos Santos Dias, Elaine M. Kohn, Junfeng Huang, M. Suresh, Marcel Wüthrich, Christina L. Gomez, Cleison Ledesma Taira, Huafeng Wang, Lingjun Li, Charles A. Specht, J. Scott Fites, Gregory C. Kujoth, Parastoo Azadi, Daisy Gates
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009324 (2021)
PLoS Pathogens
PLoS Pathogens
The development of safe subunit vaccines requires adjuvants that augment immunogenicity of non-replicating protein-based antigens. Current vaccines against infectious diseases preferentially induce protective antibodies driven by adjuvants such as al
Autor:
John F. Kernien, Michael Feldman, Shuying Xu, Paige E. Negoro, Allison K. Scherer, Alex Hopke, Jennifer L. Reedy, Jeniel E. Nett, Daniel Irimia, Natalie J. Alexander, J. Scott Fites, Nida S. Khan, Michael K. Mansour, Zeina Dagher, Richard A. Dutko, Jatin M. Vyas, Natalie J. Atallah, Bruce S. Klein, Adam Viens, David B. Sykes, Jane B Jeffery
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
mBio, Vol 11, Iss 3, p e02043-19 (2020)
mBio, Vol 11, Iss 3, p e02043-19 (2020)
Invasive fungal infections constitute a lethal threat, with patient mortality as high as 90%. The incidence of invasive fungal infections is increasing, especially in the setting of patients receiving immunomodulatory agents, chemotherapy, or immunos
Autor:
Nydiaris Hernández-Santos, Richard M. Merkhofer, J. Scott Fites, Hannah E. Dobson, Abigail C. Shockey, Bruce S. Klein, Marcel Wuethrich, Mary B. O’Neill, Donny Xiong, Caitlin S. Pepperell
Publikováno v:
mBio, Vol 10, Iss 3, p e01224-19 (2019)
mBio
mBio, Vol 10, Iss 3 (2019)
mBio
mBio, Vol 10, Iss 3 (2019)
Blastomycosis is a potentially life-threatening infection caused by the fungus Blastomyces dermatitidis. As with related fungal diseases, blastomycosis is noted to affect some populations more than others. These patterns of illness are often not rela