Zobrazeno 1 - 10
of 49
pro vyhledávání: '"J. A. Fernandez-Pol"'
Autor:
J Alberto, Fernandez-Pol
Publikováno v:
Cancer genomicsproteomics. 13(1)
The ribosomal protein metallopanstimulin-1 (MPS1/S27) serves critical survival purposes in cell division, in normal and cancerous cells; for this reason, selective pressures of evolution have conserved the DNA sequences encoding MPS1/S27 in Archaea a
Publikováno v:
Hematology/Oncology Clinics of North America. 14:25-44
This vain presumption of understanding everything can have no other basis than never understanding anything … For anyone who had experienced just once the perfect understanding of one single thing [and had truly tasted how knowledge is accomplished
Autor:
J Alberto, Fernandez-Pol
Publikováno v:
Cancer genomicsproteomics. 9(4)
When a protein has a useful and unique function, the selective pressures of evolution conserve the DNA sequences encoding such proteins; the conservation of these domains may have pragmatic use in better understanding viral and spontaneous carcinogen
Autor:
J Alberto, Fernandez-Pol
Publikováno v:
Cancer genomicsproteomics. 8(3)
When the functions of a protein serve a useful survival and unique purpose, the selective pressures of evolutionary laws of nature conserve the DNA sequences encoding such proteins. In many instances, the conservation of these sequences has occurred
Publikováno v:
Journal of Biological Chemistry. 268:21198-21204
Growth factors rapidly induce numerous genes that encode regulatory proteins, many of which have been identified by cDNA cloning. In this study, differential hybridization was used to screen a cDNA library constructed from human mammary carcinoma MDA
Publikováno v:
Cancer genomicsproteomics. 2(1)
We have used genomics and proteomics based technologies to study tissue and serum protein profiles in patients with breast cancer (BC) in comparison to control healthy subjects. One critical objective of this study was to identify and characterize ne
Autor:
Eduardo M Diaz, Toni M Ganzel, Brendan C Stack, J Paul Hansen, James Ruda, Joseph Shvidler, J Albert Fernandez‐Pol
Publikováno v:
Otolaryngology–Head and Neck Surgery. 129
Publikováno v:
Cancer detection and prevention. 25(3)
We have previously shown that human metallopanstimulin-1 (MPS-1) is a ubiquitous 9.4-kd multifunctional ribosomal S27/nuclear "zinc finger" protein that is expressed at high levels in a wide variety of actively proliferating cells and tumor tissues.
Publikováno v:
Anticancer research. 21(2A)
In this review the authors summarize the experimental data on the role of a selected group of metalloproteins, particularly viral (v) and cellular (c) zinc finger proteins (ZFP) and iron containing proteins which are involved in cell proliferation, n
Publikováno v:
In vivo (Athens, Greece). 15(2)
Hemopoietic cells, the extracellular matrix, growth factors and the microenvironment are involved in the regulation of hemopoiesis. Although the regulation of erythropoiesis is well understood at the cellular level in vivo and in vitro, the role of h