Výsledky vyhledávání - "J. A. D. M. de Roos"

Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis

Autor: Ruud A. Bank, J. A. D. M. de Roos, Johan M. TeKoppele, F. C. Breedveld, Johan Hendrikus Verheijen, W.H. van der Laan, H.K. Ronday, Paul P. Tak, Christopher J. Froelich, Cornelis Erik Hack, Pancras C.W. Hogendoorn

Publikováno v: Scopus-Elsevier
Rheumatology, 1, 40, 55-61
Rheumatology (Oxford, England), 40(1), 55-61. Oxford University Press

Objective. To investigate the cartilage-degrading capacity of granzyme B and the presence of granzyme B-positive cells at sites of erosion in the rheumatoid synovium. Methods. Granzyme B was added to [3H]proline/[35S]sulphate-labelled cartilage matri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edfd5d908b166aa777151bb69eee6bf2
https://doi.org/10.1093/rheumatology/40.1.55

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Tranexamic acid, an inhibitor of plasminogen activation, reduces urinary collagen cross-link excretion in both experimental and rheumatoid arthritis

Autor: B A C Dijkmans, J. A. D. M. de Roos, R. A. Greenwald, H.K. Ronday, J. M. Te Koppele, Johan Hendrikus Verheijen, S. A. Moak, F. C. Breedveld

Publikováno v: British journal of rheumatology, 1, 37, 34-38

The plasminogen activation system is one of the enzyme systems held responsible for bone and cartilage degradation in rheumatoid arthritis (RA). In this study, we evaluated the effect of tranexamic acid (TEA), an inhibitor of plasminogen activation,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c26028a66a008883626e9394c26c467
https://doi.org/10.1093/rheumatology/37.1.34

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Collagen-induced arthritis in rhesus monkeys: evaluation of markers for inflammation and joint degradation

Autor: J. A. D. M. de Roos, Herbert P.M. Brok, B. A. ‘t Hart, Ruud A. Bank, J. M. Te Koppele, Margreet Jonker, J. Hakimi, H.M. Theuns

Publikováno v: Europe PubMed Central
British Journal of Rheumatology, 3, 37, 314-323

The objective of this study was to analyse parameters in rhesus monkey collagen-induced arthritis (CIA) with which the inflammation and destruction of the joints can be described in quantitative terms. CIA was induced in genetically susceptible and r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd91b9def764bba554f3f31d1a4e425
http://europepmc.org/abstract/med/9566674

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