Výsledky vyhledávání - "J. K. Nicholson"

Akademický článek

Adipose Tissue‐Resident Sphingomonas Paucimobilis Suppresses Adaptive Thermogenesis by Reducing 15‐HETE Production and Inhibiting AMPK Pathway.

Autor: Zhu, Yucheng¹ (AUTHOR), Yang, Ruiqi¹ (AUTHOR), Deng, Zhangchao¹ (AUTHOR), Deng, Bohua¹ (AUTHOR), Zhao, Kun² (AUTHOR), Dai, Chen³ (AUTHOR), Wei, Gang⁴ (AUTHOR), Wang, YanJiang⁵ (AUTHOR), Zheng, Jinshui⁶ (AUTHOR), Ren, Zhuqing¹ (AUTHOR), Lv, Wentao⁷ (AUTHOR), Xiao, Yingping⁷ (AUTHOR) xiaoyp@zaas.ac.an, Mei, Zhinan⁸ (AUTHOR) meizhinan@mail.hzau.edu.cn, Song, Tongxing¹ (AUTHOR) songtongxing@mail.hzau.edu.cn

Publikováno v: Advanced Science. 12/18/2024, Vol. 11 Issue 47, p1-17. 17p.

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Akademický článek

Hepatocyte‐Targeted Lipid Nanoparticle Delivery of HERC2 Plasmid Controls Drug‐Induced Hepatotoxicity by Limiting β‐Catenin‐Regulated CYP2E1 Expression.

Autor: Liu, Yunzhi^1,2,3 (AUTHOR), Xu, Qishan^1,4 (AUTHOR), Liu, Yan¹ (AUTHOR), Cao, Sihang^1,5 (AUTHOR), Luo, Jialiang^1,6 (AUTHOR), Zheng, Zhuojun^1,7,8 (AUTHOR), Zhou, Jia⁶ (AUTHOR), Lu, Xiao⁶ (AUTHOR), Zhang, Liyun⁶ (AUTHOR), Tan, Yanan^2,9 (AUTHOR) tanyn@hku-szh.org, Chen, Qingyun⁷ (AUTHOR) chenqingyun@gdph.org.cn, Zuo, Daming^1,8 (AUTHOR) zdaming@smu.edu.cn

Publikováno v: Advanced Science. 12/11/2024, Vol. 11 Issue 46, p1-13. 13p.

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Detection of mono- and di-hexoses as metabolites of 4-bromoaniline using HPLC-TOF-MS/MS

Autor: Ian D. Wilson, Hilary Major, Jose Castro-Perez, J. K. Nicholson

Publikováno v: Xenobiotica. 33:855-869

1. The metabolic fate of 4-bromoaniline (4-BrA) was investigated in rat following intraperitoneal administration at 50 mg kg(-1) using HPLC-TOF-MS/MS. 2. The sensitivity provided by the use of TOF-MS/MS, aided by the distinctive isotope pattern resul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47667f6d106d0e69068c10f3218dd3c
https://doi.org/10.1080/0049825031000121590

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Application of 1 H- and 19 F-NMR spectroscopy in the investigation of the urinary and biliary excretion of 3,5-, 2,4-ditrifluoromethylbenzoic and pentafluorobenzoic acids in rat

Autor: Ian D. Wilson, J. K. Nicholson, C. A. Blackledge, J. A. Evans, C. Rodgers

Publikováno v: Xenobiotica. 32:605-613

1. The metabolism and excretion of 2,4-, 3,5-ditrifluoromethyl- and pentafluorobenzoic acids were studied in the bile-cannulated rat using (1)H- and (19)F-NMR spectroscopy following intraperitoneal administration at 50 mg kg(-1). 2. Pentafluorobenzoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ee6032a10a3831ef4d2c173be42c85
https://doi.org/10.1080/00498250210131590

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Akademický článek

Application of ¹ H NMR Metabolic Profiling of Serum in Canine Multicentric Lymphoma.

Autor: Solé RS; Laboratorio de Análisis Clínicos, Departamento de Clínicas y Hospital Veterinario, Facultad de Veterinaria, Universidad de la República, Montevideo, Uruguay., Radcenco AL; Laboratorio de Fisicoquímica Orgánica, Departamento de Química del Litoral, CENUR Litoral Norte, Universidad de la República, Paysandú, Uruguay., Moyna G; Laboratorio de Fisicoquímica Orgánica, Departamento de Química del Litoral, CENUR Litoral Norte, Universidad de la República, Paysandú, Uruguay., Breijo M; Unidad de Reactivos y Biomodelos de Experimentación, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay., Pessina P; Laboratorio de Análisis Clínicos, Departamento de Clínicas y Hospital Veterinario, Facultad de Veterinaria, Universidad de la República, Montevideo, Uruguay.

Publikováno v: Veterinary and comparative oncology [Vet Comp Oncol] 2024 Dec 08. Date of Electronic Publication: 2024 Dec 08.

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A (1)H NMR spectroscopic study of the biochemical effects of ifosfamide in the rat: evaluation of potential biomarkers

Autor: John A. Timbrell, E. M. Lenz, J K Nicholson, I D Wilson

Publikováno v: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 5(6)

Ifosfamide (55 mg kg(-1) and 110 mg kg(-1)) was administered via single i.p. injections to Sprague-Dawley rats and urine samples were collected for the periods of -24-0, 0-8 h, 8-24 h, 24-48 h and 48-72 h post-dose. Quantitative changes in the excret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d5bde5fb6ec43167222c0f399bdc35a
https://pubmed.ncbi.nlm.nih.gov/23898813

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