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Transcription of a centromere-enriched retroelement and local retention of its RNA are significant features of the CENP-A chromatin landscape

Autor: B. J. Chabot, R. Sun, A. Amjad, S. J. Hoyt, L. Ouyang, C. Courret, R. Drennan, L. Leo, A. M. Larracuente, L. J. Core, R. J. O’Neill, B. G. Mellone

Publikováno v: Genome Biology, Vol 25, Iss 1, Pp 1-34 (2024)

Abstract Background Centromeres depend on chromatin containing the conserved histone H3 variant CENP-A for function and inheritance, while the role of centromeric DNA repeats remains unclear. Retroelements are prevalent at centromeres across taxa and

Externí odkaz: https://doaj.org/article/09b23b65796b4c6db7fd00ff83b922a1

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Akademický článek

Expression profiling identifies key genes and biological functions associated with eosinophilic esophagitis in human patients

Autor: Holly A. Morrison, Kacie J. Hoyt, Christina Mounzer, Hannah M. Ivester, Barrett H. Barnes, Bryan Sauer, Emily C. McGowan, Irving C. Allen

Publikováno v: Frontiers in Allergy, Vol 4 (2023)

IntroductionEosinophilic Esophagitis (EoE) is a chronic allergic disease characterized by progressive inflammation of the esophageal mucosa. This chronic inflammatory disorder affects up to 50 per 100,000 individuals in the United States and Europe y

Externí odkaz: https://doaj.org/article/01aa983b8a3840cfb24b12c5eddd6819

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Coordinated JWST Imaging of Three Distance Indicators in a Supernova Host Galaxy and an Estimate of the Tip of the Red Giant Branch Color Dependence

Autor: Taylor J. Hoyt, In Sung Jang, Wendy L. Freedman, Barry F. Madore, Abigail J. Lee, Kayla A. Owens

Publikováno v: The Astrophysical Journal, Vol 975, Iss 1, p 111 (2024)

Boasting a 6.5 m mirror in space, JWST can increase by several times the number of supernovae (SNe) to which a redshift-independent distance has been measured with a precision distance indicator (e.g., tip of the red giant branch (TRGB) or Cepheids);

Externí odkaz: https://doaj.org/article/4a8f6d4855e14ae4a111685c848dcf2b

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Akademický článek

Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis

Publikováno v: Frontiers in Immunology, Vol 13 (2023)

T peripheral helper (Tph) cells, identified in the synovium of adults with seropositive rheumatoid arthritis, drive B cell maturation and antibody production in non-lymphoid tissues. We sought to determine if similarly dysregulated T cell-B cell inte

Externí odkaz: https://doaj.org/article/2e6fb3b7d8f946bf87162e8a9df346f1

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Akademický článek

Polarization-sensitive optical coherence tomography monitoring of percutaneous radiofrequency ablation in left atrium of living swine

Autor: Xiaowei Zhao, Ohad Ziv, Reza Mohammadpour, Benjamin Crosby, Walter J. Hoyt, Michael W. Jenkins, Christopher Snyder, Christine Hendon, Kenneth R. Laurita, Andrew M. Rollins

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract Radiofrequency ablation (RFA) is commonly used to treat atrial fibrillation (AF). However, the outcome is often compromised due to the lack of direct real-time feedback to assess lesion transmurality. In this work, we evaluated the ability o

Externí odkaz: https://doaj.org/article/7f23977f72e2400a90c4496859aefa05

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Akademický článek

Controlling solid-liquid interfacial energy anisotropy through the isotropic liquid

Autor: Lei Wang, Jeffrey J. Hoyt, Nan Wang, Nikolas Provatas, Chad W. Sinclair

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-7 (2020)

In metals, dendrite orientation during crystal growth has been hypothesized to be affected by compositional additions. Here, the authors combine molecular dynamics and experiments in the aluminium-samarium system to prove solute atoms can affect dend

Externí odkaz: https://doaj.org/article/cd286ae37f6b4b8690aa78ec732e5798

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Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis

Publikováno v: JCI Insight, Vol 6, Iss 18 (2021)

Oligoarticular juvenile idiopathic arthritis (oligo JIA) is the most common form of chronic inflammatory arthritis in children, yet the cause of this disease remains unknown. To understand immune responses in oligo JIA, we immunophenotyped synovial f

Externí odkaz: https://doaj.org/article/c04a1ff5d5564d88b779915faecc85da

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