H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing

Autor: Julia Roensch, Ana Cláudia Raposo, Tetsuya Handa, Jumpei Nogami, Aurelie Bousard, Yasuyuki Ohkawa, Tomoya Kujirai, Sandra Bagés-Arnal, Akito Ohi, Simão Teixeira da Rocha, Yuko Sato, Sjoerd J. D. Tjalsma, Hitoshi Kurumizaka, Edith Heard, Jan J. Żylicz, Mayako Hori, Hiroshi Kimura, Agnes Le Saux, Kazumitsu Maehara

Publikováno v: Tjalsma, S J D, Hori, M, Sato, Y, Bousard, A, Ohi, A, Raposo, A C, Roensch, J, Le Saux, A, Nogami, J, Maehara, K, Kujirai, T, Handa, T, Bages-Arnal, S, Ohkawa, Y, Kurumizaka, H, da Rocha, S T, Zylicz, J J, Kimura, H & Heard, E 2021, ' H4K20me1 and H3K27me3 are concurrently loaded onto the inactive X chromosome but dispensable for inducing gene silencing ', EMBO Reports, vol. 22, no. 3, 51989 . https://doi.org/10.15252/embr.202051989
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During X chromosome inactivati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fa9cb7ddca333e7c2a262d52d5687b2
https://curis.ku.dk/ws/files/280117752/embr.202051989.pdf

SPEN integrates transcriptional and epigenetic control of X-inactivation

Autor: Damarys Loew, François Dossin, Varun Kapoor, Mikael Attia, Julia Roensch, Ye Zhan, Tomasz Chelmicki, Agnes Le Saux, Inês Pinheiro, Jan J. Żylicz, Florent Dingli, Samuel Collombet, Job Dekker, Thomas Mercher, Edith Heard

Publikováno v: Nature

Xist represents a paradigm for the function of long non-coding RNA in epigenetic regulation, although how it mediates X-chromosome inactivation (XCI) remains largely unexplained. Several proteins that bind to Xist RNA have recently been identified, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38fe239c7b5e193a6ad987142b0849a

The role of Xist‐mediated Polycomb recruitment in the initiation of X‐chromosome inactivation

Autor: Ana Cláudia Raposo, Vanessa Borges Pires, Christel Picard, Laurène Syx, Edith Heard, Jan J. Żylicz, Aurelie Bousard, Yanyan Qi, Howard Y. Chang, Simão Teixeira da Rocha, Cláudia Gil

Publikováno v: EMBO Reports
EMBO reports

Xist RNA has been established as the master regulator of X‐chromosome inactivation (XCI) in female eutherian mammals, but its mechanism of action remains unclear. By creating novel Xist‐inducible mutants at the endogenous locus in male mouse embr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5cbd66ec5088479184f1fd2087a815
http://europepmc.org/articles/PMC6776897

The Implication of Early Chromatin Changes in X Chromosome Inactivation

Autor: Björn Schwalb, François Dossin, Florent Dingli, Damarys Loew, Patrick Cramer, Jan J. Żylicz, Simão Teixeira da Rocha, Kristina Žumer, Eusra Mohammad, Laurène Syx, Aurelie Bousard, Edith Heard

Publikováno v: Cell
Cell, Elsevier, 2019, 176 (1-2), pp.182-197.e23. ⟨10.1016/j.cell.2018.11.041⟩

Summary During development, the precise relationships between transcription and chromatin modifications often remain unclear. We use the X chromosome inactivation (XCI) paradigm to explore the implication of chromatin changes in gene silencing. Using

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ba0666cecb6a2546fb827a816837d6

Evidence for the virtualβ−γtransition inNi59decay

Autor: M. Pfützner, Krzysztof Pachucki, J. Żylicz

Publikováno v: Physical Review C. 92

The authors present first evidence for the contribution of a virtual $\ensuremath{\beta}$-$\ensuremath{\gamma}$ transition---a second-order process---to the radiative electron-capture decay of ${}^{59}$Ni. The key feature is a reliable theory of radi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f8870ad31b932c6b97b4d0e6fb661c9f
https://doi.org/10.1103/physrevc.92.044305