Zobrazeno 1 - 10
of 26
pro vyhledávání: '"J.‐P. Bats"'
Publikováno v:
Helvetica Chimica Acta. 87:2695-2705
The latest route to Ambrox® (1) starting from sclareol (2) proceeds through an oxy ketone 4 (Scheme 1). A new practical synthesis of the key intermediate 4 is described; it is equivalent to a partial oxidative degradation of sclareol (2) with perace
Publikováno v:
Synthetic Communications. 23:2991-2998
(+)-13-Epimanoyl oxide has been synthesised in four steps from natural sclareol in an overall yield of 78%; preparation of the related labdane-14,15-diols is involved in this synthetic pathway.
Publikováno v:
Tetrahedron Letters. 34:2315-2318
N-tosyl-oxiraneethylamines undergo cyclization upon treatment with aqueous sodium hydroxide to afford either N-tosyl-azetidinemethanols or N-tosyl-pyrrolidin-3-ols in high yields. The change in regioselectivity of this cyclization process is quite de
Publikováno v:
ChemInform. 23
Publikováno v:
ChemInform. 24
Publikováno v:
ChemInform. 25
(+)-13-Epimanoyl oxide has been synthesised in four steps from natural sclareol in an overall yield of 78%; preparation of the related labdane-14,15-diols is involved in this synthetic pathway.
Publikováno v:
Tetrahedron Letters. 33:487-490
The reaction of N-tosly-oxiranemethylamines with aqueous sodium hydroxide affords N-tosyl-aziridinemethanols in excellent yields, through the intramolecular epoxide ring opening by the nitrogen atom of the tosylamino group.
Publikováno v:
ChemInform. 36
Publikováno v:
Tetrahedron. 38:2139-2146
Oxiraneethoxytributyltins prepared from the corresponding oxiraneethanols, on heating at ∼ 200° gave, after demetalation with isophthallic acid, 2-oxetanemethanols and/or 3-oxolanols. As appears from about thirty rearrangements the choice between
Publikováno v:
Tetrahedron Letters. 21:3051-3054
The transposition of oxirane-ethanols, through alkoxytin compounds, into oxetane-2-methanols and/or oxolan-3-ols (tetrahydrofuran-3-ols) is dependent upon the oxirane configuration. Cis configuration is more suitable for the formation of the smallest