Zobrazeno 1 - 10
of 164
pro vyhledávání: '"J.‐C. Florent"'
Publikováno v:
European Journal of Organic Chemistry. 1998:2417-2423
Autor:
Cyrille Kuhn, J.‐C. Florent
Publikováno v:
Tetrahedron Letters. 39:4247-4250
An efficient and stereoselective synthesis of a chiral precursor of 2-chloro-4-hydroxy-4-alkyl-2-cyclopentenone has been realized by alkylation of a sugar methyl uronate derived from 1, 2-O-isopropylidene α-D-glucose with an acetonyl equivalent, and
Publikováno v:
Synthetic Communications. 28:61-73
Synthesis of silylglycosides of 3-azido-2-deoxy-L-arabino- and ribo-hexopyranoses 4 and 5 has been achieved in 3 steps and 44,6% and 18% overall yields, respectively. The corresponding N-trifluoroacetamido derivatives 9 and 10 were further prepared i
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1815-1818
A furo[2,3- c ]pyran-β-D-thymidine nucleoside analog was synthesized from 5′-O-TBDMS-3′-C-allyl-thymidine by 4′-C-hydroxymethylation followed by an electrophilic 6-membered ring annellation. The new bicyclonucleoside was devoid of activity aga
Publikováno v:
Tetrahedron Letters. 36:3137-3140
A convenient construction of chiral 4-hydroxy 2-cyclopentenones from α-alkoxy aldehyde 6 derived from sugar is reported. A mechanism is proposed involving imine-enamine equilibrium, then alkylation with 2-alkoxypropenyl iodide followed by a tandem 3
Publikováno v:
Synthesis. 1994:939-943
Autor:
Claude Monneret, J.‐C. Florent
Publikováno v:
Synlett. 1994:305-318
Publikováno v:
Journal of Controlled Release. 74:255-257
The ectopeptidase gamma-glutamyltranspeptidase (gamma-GT) is overexpressed in myeloid leukemias. Its specific inhibitor, acivicin, was previously shown to induce an inhibitory growth effect associated with an induction of morphological features chara
Publikováno v:
ChemInform. 23
The synthesis of 2'-C-hydroxymethyl and 2'-C-methyl nucleoside analogs [1-(3-deoxy-2-hydroxymethyl-D-erythro-pentofuranosyl)-thymine , the corresponding adenine derivative. 1-(2-methyl-β-D-ribofuranosyl)thymine and 2'-methyladenosine ] by coupling o
Publikováno v:
ChemInform. 22