Zobrazeno 1 - 10 of 1 243 pro vyhledávání: '"J., Ehrlich"'
1
Akademický článek
A randomized feasibility trial of medium chain triglyceride-supplemented ketogenic diet in people with Parkinson's disease
Autor: Alexander H. Choi, Melanie Delgado, Kong Y. Chen, Stephanie T. Chung, Amber Courville, Sara A. Turner, Shanna Yang, Kayla Airaghi, Irene Dustin, Patrick McGurrin, Tianxia Wu, Mark Hallett, Debra J. Ehrlich
Publikováno v: BMC Neurology, Vol 24, Iss 1, Pp 1-19 (2024)
Abstract Background A ketogenic diet (KD) may benefit people with neurodegenerative disorders marked by mitochondrial depolarization/insufficiency, including Parkinson’s disease (PD). Objective Evaluate whether a KD supplemented by medium chain tri
Externí odkaz: https://doaj.org/article/2cb7bc56ea784b6abf82c1a6c4f0312e
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2
Akademický článek
Article review: Multi-omics for studying and understanding polar life
Autor: A. Graiff, J. Ehrlich
Publikováno v: Polarforschung, Vol 92, Pp 25-26 (2024)
Externí odkaz: https://doaj.org/article/6f7adb32a0ca4887a076a30ee2a8229d
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3
Akademický článek
ABX464 (obefazimod) for patients with COVID-19 at risk for severe disease: miR-AGE, a randomized, double-blind placebo-controlled trial
Autor: Pedro Giavina-Bianchi, MD, PhD, Eric Cua, MD, Karine Risso, MD, Véronique Mondain, MD, Anaïs Vissian, MSc, Cécile Joie, MSc, Philippe Pouletty, MD, Paul Gineste, PharmD, Hartmut J. Ehrlich, MD, PhD, Jorge Kalil, MD, PhD
Publikováno v: Journal of Allergy and Clinical Immunology: Global, Vol 2, Iss 4, Pp 100140- (2023)
Background: ABX464 (obefazimod) is a small molecule that upregulates a single microRNA (miR-124) in immune cells and reduces the production of various inflammatory cytokines and chemokines. Objective: We assessed the efficacy and safety of the standa
Externí odkaz: https://doaj.org/article/38018d98dfd24036bb65e23f3e7a3be0
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5
Elektronická kniha
Hate Crimes and Ethnoviolence : The History, Current Affairs, and Future of Discrimination in America
Autor: Howard J Ehrlich
Over the past twenty years, Howard J. Ehrlich conducted the first national surveys of ethnoviolence, helped design the protocol for identifying hate crimes, and has served as the director of The Prejudice Institute. This collection of essays is the r
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6
Akademický článek
Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phase IIa randomised controlled study
Autor: Sofie Rutsaert, Jean-Marc Steens, Paul Gineste, Basiel Cole, Sam Kint, P. Noel Barrett, Jamal Tazi, Didier Scherrer, Hartmut J. Ehrlich, Linos Vandekerckhove
Publikováno v: Journal of Virus Eradication, Vol 5, Iss 1, Pp 10-22 (2019)
Objectives: To assess the safety and tolerability as well as antiretroviral impact of ABX464, an oral investigational drug with a novel mechanism of HIV-1 inhibition (ClinicalTrials.gov NCT02735863). Methods: Randomised, double-blind, placebo-control
Externí odkaz: https://doaj.org/article/3ef3f0db63364cc288365e8f7330998c
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9
Demonstration of the Antitumor Activity of the iNKT Agonist ABX196, a Novel Enhancer of Cancer Immunotherapy, in Melanoma and Hepatocarcinoma Mouse Models
Autor: Didier Scherrer, Noel Barrett, Luc Teyton, Tillman Pearce, Josianne Nitcheu, Philippe Pouletty, Julien Santo, Hartmut J. Ehrlich
Publikováno v: Molecular Cancer Therapeutics. 21:1788-1797
Immune checkpoint blockers (ICB) provide a promising approach to antitumor immunotherapy through blockade of immunosuppressive pathways. The synthetic glycolipid, ABX196, is a potent stimulator of invariant natural killer T cells (iNKT), a small subs
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9511278906cbb4781ed51358308534dc
https://doi.org/10.1158/1535-7163.mct-22-0183
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10
Akademický článek
The Anti-Hiv Candidate Abx464 Dampens Intestinal Inflammation by Triggering Il-22 Production in Activated Macrophages
Autor: Karim Chebli, Laura Papon, Conception Paul, Aude Garcel, Noëlie Campos, Didier Scherrer, Hartmut J. Ehrlich, Michael Hahne, Jamal Tazi
Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The progression of human immunodeficiency virus (HIV) is associated with mucosal damage in the gastrointestinal (GI) tract. This damage enables bacterial translocation from the gut and leads to subsequent inflammation. Dextran sulfate sodium
Externí odkaz: https://doaj.org/article/908d748ddfcb49b68fb516df8640bcdd
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