Zobrazeno 1 - 10
of 32
pro vyhledávání: '"J-J. Mermod"'
Publikováno v:
The Journal of Immunology. 146:3419-3423
Eosinophils, through their ability to generate an array of potent mediators, are thought to be the major effector cells in a number of conditions, including parasitic infection, asthma, and other allergic diseases. The mechanism(s) by which eosinophi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::931e108829c3b8fbc28ca16ec7ae865f
https://doi.org/10.4049/jimmunol.146.10.3419
https://doi.org/10.4049/jimmunol.146.10.3419
Publikováno v:
American journal of medical genetics. 74(2)
The presence of one or two apoliprotein E4 (apoE4) alleles constitutes a major risk factor for Alzheimer's disease (AD) and coronary heart disease (CHD). Numerous observations have suggested that misregulation of proteases may be instrumental in both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3f6e40330208f33ca671f95b9c8734d
https://pubmed.ncbi.nlm.nih.gov/12116244
https://pubmed.ncbi.nlm.nih.gov/12116244
Autor:
J J Mermod, J F DeLamarter, A Proudfoot, S Alouani, R Pescini, C Power, R Hooft van Huijsduijnen
Publikováno v:
Biochemical and biophysical research communications. 202(3)
A regulatable binary expression system for eukaryotes was recently developed based on the tetracycline repressor and its operator. Here we show that this system can be successfully applied to express antisense RNA and completely inhibit gene expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140f943ccdfc04ee8c750c0a9e4699bc
https://pubmed.ncbi.nlm.nih.gov/8060354
https://pubmed.ncbi.nlm.nih.gov/8060354
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(2)
We recently described an IL-1 inhibitor found in urine of febrile patients. It is a 26-kDa glycoprotein that acts by blocking the binding of IL-1 to its receptor. In a search for a cell source for the urinary IL-1 inhibitor, we tested three promyeloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adf345a7c1ea9167dba288f6299ed64d
https://pubmed.ncbi.nlm.nih.gov/2142181
https://pubmed.ncbi.nlm.nih.gov/2142181
Publikováno v:
The EMBO Journal. 4:2575-2581
We report the production and characterization of a mouse granulocyte-macrophage colony stimulating factor (mGM-CSF) made in Escherichia coli. The synthesis of mGM-CSF was directed by a plasmid containing a gene isolated from the EL-4 cell line. After
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806951c0dfb2ab9ccc147a37ff481508
https://doi.org/10.1002/j.1460-2075.1985.tb03973.x
https://doi.org/10.1002/j.1460-2075.1985.tb03973.x
Autor:
D J Williamson, J.-J. Mermod, JF DeLamarter, Richard J. Simpson, A Schmitz, Angel F. Lopez, Colin Glenn Begley, Gregory R. Johnson, Antony W. Burgess
Publikováno v:
Blood. 69:43-51
Human granulocyte-macrophage colony stimulating factor (GM-CSF) has been synthesized in high yield using a temperature inducible plasmid in Escherichia coli. The human GM-CSF is readily isolated from the bacterial proteins because of its differential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc6a4337ad3571fc0e86c24b264227ff
https://doi.org/10.1182/blood.v69.1.43.43
https://doi.org/10.1182/blood.v69.1.43.43
Autor:
S.G. Amara, G.D. Aurbach, K.L. Barker, A-L. Barofsky, F.C. Bartter, J.D. Baxter, J.C. Beck, L. Bilezikjian, N.C. Birnberg, F. Bloom, P. Boyd-Leinen, M.R. Brown, C.P. Channing, B. Chatterjee, L.W.K. Chung, S.L. Cohen, D.V. Cohn, W.F. Crowley, G.R. Cunha, G.B. Cutler, W.F. Demyan, D.E. Dobson, B.M. Dobyns, P.K. Donahoe, R.A. Edgren, J. Elting, R.M. Evans, L.L. Ewing, H. Fujii, J.D. Gardner, J.R. Gill, A.L. Goodman, R.O. Greep, J.R. Grove, C.V. Hall, D.H. Hamer, G.D. Hodgen, R.A. Huseby, J.M. Hutson, L.S. Jacobs, R.T. Jensen, R. Jewelewicz, V.C. Jordan, A.D. Kenny, O.L. Kon, T. Kono, G. Koob, I.A. Kourides, J. Larner, C. Lazier, F. Lee, R. Levine, D.M. Linkie, B. Little, B.A. Littlefield, G.Martin Dani, J-J. Mermod, B.S. Main, F. Morel, N.M. Motwani, W. Moyle, G.H. Murdoch, T.S. Nath, M.I. New, C.S. Nicoll, M.B. Nikitovitch-Winer, R. Osathanondh, H. Papkoff, G. Pavlakis, E.J. Peck, J.C. Penhos, D.W. Pfaff, S. Plymate, J.E. Rall, B.F. Rice, G. Ringold, C. Rivier, J. Rivier, P. Robel, M.G. Rosenfeld, A.K. Roy, M. Saffran, M.J. Schiop, N.B. Schwartz, R. Seelke, A. Segaloff, J.M. Shannon, H. Shima, L. Sokoloff, T. Spelsberg, J. Spiess, K. Sterling, L. Swanson, O. Taguchi, C. Thrall, H. Toyoda, J. Vaitukaitis, W. Vale, J.L. Vannice, B. Zirkin, U. Zor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79b24ad7006b53a9ce2270bfff444b79
https://doi.org/10.1016/b978-0-12-571139-5.50003-3
https://doi.org/10.1016/b978-0-12-571139-5.50003-3
Autor:
D, Metcalf, C G, Begley, D J, Williamson, E C, Nice, J, De Lamarter, J J, Mermod, D, Thatcher, A, Schmidt
Publikováno v:
Experimental hematology. 15(1)
Normal adult BALB/c, C57BL, and C3H/HeJ mice were injected intraperitoneally three times daily for six days with 6-200 ng purified, bacterially synthesized, murine recombinant GM-CSF. Mice injected with 200 ng rGM-CSF developed a twofold increase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ea95286f33df41f687f432a73add597
https://pubmed.ncbi.nlm.nih.gov/3490993
https://pubmed.ncbi.nlm.nih.gov/3490993
The control of haematopoietic colony-stimulating factors (CSF) gene expression by interleukin 1 (IL-1) and tumour necrosis factor alpha (TNF-alpha) in cultured endothelial cells was studied by RNA hybridization and nuclear gene transcription. Both IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb223fe144869361974ddba8e2a86b83
https://europepmc.org/articles/PMC553627/
https://europepmc.org/articles/PMC553627/