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pro vyhledávání: '"J-C. Levy"'
Akademický článek
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Akademický článek
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Autor:
Mark I. McCarthy, Graham A. Hitman, Andrew T. Hattersley, Parkinson Jrc., C J Groves, Stephen O'Rahilly, Eleftheria Zeggini, Mark Walker, S. Halford, Katharine R. Owen, J C Levy, Timothy M. Frayling
AIMS/HYPOTHESIS: The proinflammatory cytokine TNF-alpha has been implicated in the pathogenesis of insulin resistance and type 2 diabetes, and variation in the gene encoding TNF-alpha (TNF) has shown inconsistent associations with susceptibility to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02332191ec1c19424fa8e01c9ccac441
https://ora.ox.ac.uk/objects/uuid:b9775116-e0f8-4951-ab70-d4136f9bb1e8
https://ora.ox.ac.uk/objects/uuid:b9775116-e0f8-4951-ab70-d4136f9bb1e8
A mathematical model of normal glucose/insulin homoeostasis has been based on the known, experimentally determined responses of the liver and periphery to different glucose/insulin concentrations. Different defects of glucose resistance and insulin r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f841ea09cc3ad1155409bb285369ff
https://ora.ox.ac.uk/objects/uuid:f0e1a984-edb6-4ce0-b926-b13735e3c912
https://ora.ox.ac.uk/objects/uuid:f0e1a984-edb6-4ce0-b926-b13735e3c912
Plasma insulin, intact proinsulin and 32–33 split proinsulin measured by specific immunoradiometric assays and insulin and C-peptide measured by radioimmunoassay were measured during a constant infusion of glucose test in ten diet-treated subjects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedc559e6efb8470aa26e6996cfa8d21
https://ora.ox.ac.uk/objects/uuid:11c0a1a3-69a0-494f-ad6f-fef981694bf9
https://ora.ox.ac.uk/objects/uuid:11c0a1a3-69a0-494f-ad6f-fef981694bf9
Autor:
K N Frayn, A. von zur Mühlen, R J Morris, Rüdiger Horn, A. Widjaja, Georg Brabant, S M Humphreys, R C Turner, J C Levy
The hormone leptin is considered to contribute to body weight regulation through modulation of feeding behavior and energy expenditure. The aim of the present study was 1) to assess the day-to-day within-subject variation (biovariability) of serum le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b067a4040e09e5abc5a20ad4cf099dc
https://doi.org/10.1055/s-2000-7888
https://doi.org/10.1055/s-2000-7888
The plasma insulin or C-peptide response to a 90-min constant glucose infusion 5 mg.kg ideal body weight-1.min-1 provides Beta-cell assessment comparable to more intensive methods. In 14 diet-treated Type 2 (non-insulin-dependent) diabetic subjects a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97cc616a5b5a8c985faebd9dbe336602
https://doi.org/10.1007/bf00403285
https://doi.org/10.1007/bf00403285
Homeostatic model assessment (HOMA) is a method for assessing β-cell function and insulin resistance (IR) from basal (fasting) glucose and insulin or C-peptide concentrations. It has been reported in >500 publications, 20 times more frequently for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0a8fa8dccb6722773df55fbce2f907
https://doi.org/10.2337/diacare.27.6.1487
https://doi.org/10.2337/diacare.27.6.1487