Galactose 1-phosphate accumulates to high levels in galactose-treated cells due to low GALT activity and absence of product inhibition of GALK.

Autor: Oh SL; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Cheng LY; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., J Zhou JF; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Henke W; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Hagen T; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Publikováno v: Journal of inherited metabolic disease [J Inherit Metab Dis] 2020 May; Vol. 43 (3), pp. 529-539. Date of Electronic Publication: 2019 Dec 17.