Zobrazeno 1 - 10
of 18
pro vyhledávání: '"J Y Westcott"'
Publikováno v:
Acta Oto-Laryngologica. 117:845-850
Otitis media (OM) is an inflammatory reaction of the middle ear (ME) elicited by a variety of stimuli including tubal obstruction, allergy and bacterial infection. The leukotrienes and prostaglandins are among the earliest mediators produced in respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4287f7f3f8560493f7795f90f172e2
https://doi.org/10.3109/00016489709114212
https://doi.org/10.3109/00016489709114212
Autor:
J Y, Westcott, S E, Wenzel
Publikováno v:
Methods in molecular medicine. 56
The cysteinyl leukotrienes, comprising leukotriene (LT) C4 and its major metabolites LTD4 and LTE4, are inflammatory lipid mediators derived from metabolism of arachidonic acid by 5-lipoxygenase. These leukotrienes have received considerable attentio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c557a295e2f9e458eb42f834e3957a8
https://pubmed.ncbi.nlm.nih.gov/21336917
https://pubmed.ncbi.nlm.nih.gov/21336917
Publikováno v:
Journal of Applied Physiology. 74:1534-1542
Rapid ascent to high altitude may be associated with the development of high-altitude pulmonary edema (HAPE) in susceptible individuals. Because lung lavage fluid obtained from such patients can be rich in protein and neutrophils, we considered that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::980f7d1754c9119d823b8fa1f35c72ff
https://doi.org/10.1152/jappl.1993.74.4.1534
https://doi.org/10.1152/jappl.1993.74.4.1534
Autor:
J C Pelayo, J Y Westcott
Publikováno v:
Journal of Clinical Investigation. 88:101-105
In the present micropuncture study, the autoregulation of glomerular capillary hydrostatic pressure (PG) in Munich-Wistar rats 24 h after 75% nephrectomy (Nx) or sham operation (Sh) was investigated. The effect of varying renal perfusion pressure (RP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405e1c290a97067c3cb37793e04f354f
https://doi.org/10.1172/jci115264
https://doi.org/10.1172/jci115264
Publikováno v:
The Journal of Immunology. 146:239-243
To better define the thymic microenvironment, we have examined a specific population of thymic stromal cells, thymic nurse cells (TNC) for production of eicosanoids. TNC were prepared from BALB/c mice, cultured in complete medium, and culture superna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c820cc8f8759c33d6742aed1a229a5e0
https://doi.org/10.4049/jimmunol.146.1.239
https://doi.org/10.4049/jimmunol.146.1.239
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 259:H751-H758
The role of leukotrienes in the mechanism of hypoxic pulmonary vasoconstriction (HPV) is controversial. To determine whether leukotriene C4 (LTC4) was produced during HPV, LTC4 levels were measured in individual samples of lung tissue, lung bronchoal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752bbde7aac87f4581574a7bb0b1a0d0
https://doi.org/10.1152/ajpheart.1990.259.3.h751
https://doi.org/10.1152/ajpheart.1990.259.3.h751
Smoking of crystalline cocaine, known as "crack" cocaine, has been associated with eosinophilic pneumonitis, but not with pleural effusions. We describe a patient with eosinophilic pneumonitis with an eosinophilic "empyema" after using "crack" cocain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b28dcec7ec660cd82a63569f957d7e
https://europepmc.org/articles/PMC1746813/
https://europepmc.org/articles/PMC1746813/
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 32(11)
Although 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE), a product of 15-lipoxygenase (15-LO), may be involved in mild to moderate asthma, little is known about its potential roles in severe asthma.This study was performed to evaluate 15(S)-HETE lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::34f2521ee82e52a103592c30d2c190fd
https://pubmed.ncbi.nlm.nih.gov/12569971
https://pubmed.ncbi.nlm.nih.gov/12569971
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 9(5)
The present study in isolated rat lungs demonstrates that nitric oxide gas (.NO, 70 nM) added to the perfusate containing a small amount of hemolysate [175 microliters of lysed red blood cells (RBC) per 50 ml of Earle's balanced salt solution (EBSS)]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d6080c05818fa8e045841343ba00ea
https://pubmed.ncbi.nlm.nih.gov/7896007
https://pubmed.ncbi.nlm.nih.gov/7896007
Publikováno v:
The Journal of rheumatology. 22(3)
This is a pilot study of zileuton, a selective 5-lipoxygenase inhibitor in systemic lupus erythematosus (SLE).Forty patients with SLE received zileuton 600 mg qid or placebo in an 8 week, randomized prospective, double blind trial. Disease activity w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d1918e9c3911b622f68b4763c6e10272
https://pubmed.ncbi.nlm.nih.gov/7783062
https://pubmed.ncbi.nlm.nih.gov/7783062