Supplementary Figure S8 from Elucidating the Genetic Landscape of Oral Leukoplakia to Predict Malignant Transformation

Autor: Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils

Overview of the number of CNAs and time to progression for each of the 25 progressors. The top bars show the number of CNAs. The bottom bars show the time to progression in months. CNAs = copy number aberrations.

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https://doi.org/10.1158/1078-0432.22490485.v1

Supplementary Tables S1-2 from Elucidating the Genetic Landscape of Oral Leukoplakia to Predict Malignant Transformation

Autor: Ruud H. Brakenhoff, Elisabeth Bloemena, Jan G.A.M. de Visscher, Elisabeth R. Brouns, Ilkay Evren, Arjen Brink, Jos B. Poell, Leon J. Wils

Supplementary Table S1: Per sample sequencing characteristics; Supplementary Table S2: Co-occurrence rates and odds ratios for presence of dysplasia and investigated genomic markers.

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https://doi.org/10.1158/1078-0432.22490479.v1

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Elucidating the Genetic Landscape of Oral Leukoplakia to Predict Malignant Transformation

Autor: Leon J. Wils, Jos B. Poell, Arjen Brink, Ilkay Evren, Elisabeth R. Brouns, Jan G.A.M. de Visscher, Elisabeth Bloemena, Ruud H. Brakenhoff

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research, 29(3), 602-613. American Association for Cancer Research Inc.
Wils, L J, Poell, J B, Brink, A, Evren, I, Brouns, E R, de Visscher, J G A M, Bloemena, E & Brakenhoff, R H 2023, ' Elucidating the Genetic Landscape of Oral Leukoplakia to Predict Malignant Transformation ', Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 29, no. 3, pp. 602-613 . https://doi.org/10.1158/1078-0432.CCR-22-2210
Clinical cancer research : an official journal of the American Association for Cancer Research, 29(3), 602-613

Purpose: Oral leukoplakia is the most common oral potentially malignant disorder with an annual malignant transformation rate of 1% to 5%. Consequently, oral leukoplakia patients have a 30% to 50% lifetime risk to develop oral squamous cell carcinoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc5e81d68acc336157d422b9da1b09a
https://research.vumc.nl/en/publications/eb68a3c2-fc2a-4a15-9994-86d08cbeb5ef

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