Zobrazeno 1 - 10
of 853
pro vyhledávání: '"J William Gaynor"'
Autor:
T. Blaine Crowley, Ian Campbell, Abinaya Arulselvan, David Friedman, Elaine H. Zackai, Tracy R. Geoffrion, Char Witmer, J. William Gaynor, Donna M. McDonald-McGinn, Michele P. Lambert
Publikováno v:
Platelets, Vol 35, Iss 1 (2024)
AbstractPrevious research suggests that individuals with 22q11.2 deletion syndrome (DS) have an increased risk of bleeding following cardiac surgery. However, current guidelines for management of patients with 22q11.2DS do not provide specific recomm
Externí odkaz:
https://doaj.org/article/ad61591e3c2d4b56a2097ce4d2f856b1
Autor:
Stephanie M. Helman, PhD, Susan Sereika, PhD, Marilyn Hravnak, PhD, RN, MCCM, Richard Henker, PhD, RN, CRNA, J. William Gaynor, MD, Elizabeth Herrup, MD, Robert Olsen, BS, Patrick M. Kochanek, MD, MCCM, Rod Ghassemzadeh, MD, Tracy Baust, BA, CCRC, Nathan T. Riek, PhD(c), Yuliya Domnina, MD, Amy Jo Lisanti, PhD, RN, CCNS, Salah Al-Zaiti, PhD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 8, p e1137 (2024)
IMPORTANCE:. Persistent hypothermia after cardiopulmonary bypass (CPB) in neonates with congenital heart defects (CHD) has been historically considered benign despite lack of evidence on its prognostic significance. OBJECTIVES:. Examine associations
Externí odkaz:
https://doaj.org/article/2e1987bd65124eb3ac5afc00f0ed4c54
Autor:
Gerard H. Laurent, ScB, Tiffany S. Ko, PhD, Kobina G. Mensah-Brown, MD, MS, Constantine D. Mavroudis, MD, MSC, MTR, Marin Jacobwitz, CRNP, PhD, Nicolina Ranieri, BSc, Susan C. Nicolson, MD, J. William Gaynor, MD, Wesley B. Baker, PhD, Daniel J. Licht, MD, Shavonne L. Massey, MD, MSCE, Jennifer M. Lynch, MD, PhD
Publikováno v:
JTCVS Open, Vol 16, Iss , Pp 801-809 (2023)
Objectives: Recent research suggests that increased cerebral oxygen use during surgical intervention for neonates with congenital heart disease may play a role in the development of postoperative white matter injury. The objective of this study is to
Externí odkaz:
https://doaj.org/article/4c29f008c2cf4b1d92d84d6f9cd52cfe
Autor:
Sheri L. Balsara, MD, MS, Danielle Burstein, MD, MSCE, Richard F. Ittenbach, PhD, Michelle Kaplinski, MD, Monique M. Gardner, MD, Chitra Ravishankar, MD, Joseph Rossano, MD, David J. Goldberg, MD, Marlene Mahle, RN, Matthew J. O'Connor, MD, Christopher E. Mascio, MD, J. William Gaynor, MD, Tamar J. Preminger, MD
Publikováno v:
JTCVS Open, Vol 16, Iss , Pp 714-725 (2023)
Background: Infants with hypoplastic left heart syndrome (HLHS) or a variant are at risk of ventricular dysfunction (VD) and atrioventricular valve regurgitation (AVVR) prior to superior cavopulmonary connection (SCPC). Although the impact of these c
Externí odkaz:
https://doaj.org/article/192774d6a1a145ae8c69f2e23408c63e
Autor:
Jill Hsia, MD, Nicholas S. Abend, MD, MSCE, J. William Gaynor, MD, Jonathan M. Chen, MD, Stephanie Fuller, MD, Katsuhide Maeda, MD, PhD, Constantine D. Mavroudis, MD, MSc, MTR, Muhammad Nuri, MD, Jan Leonard, MSPH, Steve B. Ampah, PhD, Daniel J. Licht, MD, Shavonne L. Massey, MD, MSCE, Maryam Y. Naim, MD, MSCE
Publikováno v:
JTCVS Open, Vol 16, Iss , Pp 771-783 (2023)
Objectives: Historically, our center has primarily used deep hypothermic circulatory arrest, but in recent years some surgeons have selectively used regional cerebral perfusion as an alternative. We aimed to compare the incidence of postoperative ele
Externí odkaz:
https://doaj.org/article/a3dd7e7965cd4bc48730f96c09dd7975
Autor:
Richard F. Ittenbach, J. William Gaynor, Jenny M. Dorich, Nancy B. Burnham, Guixia Huang, Madisen T. Harvey, Jeremy J. Corsmo
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 12, Pp 2530-2542 (2023)
Abstract The purpose of this study was to establish the technical merit, feasibility, and generalizability of a new measure of understanding of informed consent for use with clinical research participants. A total of 109 teens/young adults at a large
Externí odkaz:
https://doaj.org/article/009bba494f53484a83bc1d3a2ea1b549
Autor:
Rasmus Kristensen, Camilla Omann, Charlotte K. Ekelund, J. William Gaynor, Vibeke E. Hjortdal
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 7 (2024)
Background Studies show that an impaired maternal–fetal environment (iMFE) increases the mortality risk in children with single‐ventricle congenital heart defects (CHDs). We investigated the impact of an iMFE on death in children with various sur
Externí odkaz:
https://doaj.org/article/4c3b10a1e2e948edba1c08982348b6cf
Autor:
Thomas A. Miller, Edgar J. Hernandez, J. William Gaynor, Mark W. Russell, Jane W. Newburger, Wendy Chung, Elizabeth Goldmuntz, James F. Cnota, Sinai C. Zyblewski, William T. Mahle, Victor Zak, Chitra Ravishankar, Jonathan R. Kaltman, Brian W. McCrindle, Shanelle Clarke, Jodie K. Votava-Smith, Eric M. Graham, Mike Seed, Nancy Rudd, Daniel Bernstein, Teresa M. Lee, Mark Yandell, Martin Tristani-Firouzi
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-9 (2023)
Abstract Background Recent large-scale sequencing efforts have shed light on the genetic contribution to the etiology of congenital heart defects (CHD); however, the relative impact of genetics on clinical outcomes remains less understood. Outcomes a
Externí odkaz:
https://doaj.org/article/c560dc3733ce40c0907a0447f485a366
Autor:
Ari J. Gartenberg, Oluwatimilehin Okunowo, Yoav Dori, Christopher L. Smith, J. William Gaynor, Christopher E. Mascio, Jonathan J. Rome, Matthew J. Gillespie, Andrew C. Glatz, Michael L. O'Byrne
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 14 (2023)
Background Intensive monitoring has been associated with a lower death rate between the Norwood operation and superior cavopulmonary connection, possibly due to early identification and effective treatment of residual anatomic lesions like recoarctat
Externí odkaz:
https://doaj.org/article/644e116452bc4d5da0c88c1c751ee295
Autor:
James K. Moon, MD, Kendall M. Lawrence, MD, Mallory L. Hunt, MD, MBE, Marcus G. Davey, PhD, Alan W. Flake, MD, Daniel J. Licht, MD, Jonathan M. Chen, MD, Todd J. Kilbaugh, MD, J. William Gaynor, MD, Daniel P. Beiting, PhD
Publikováno v:
JTCVS Open, Vol 10, Iss , Pp 342-349 (2022)
Objective: The molecular pathways underlying hypoxemia-induced alterations in neurodevelopment of infants with congenital heart disease have not been delineated. We used transcriptome analysis to investigate differential gene expression induced by hy
Externí odkaz:
https://doaj.org/article/b4695444847e46a0ad8e73509db2acf1