Zobrazeno 1 - 10
of 2 205
pro vyhledávání: '"J Widmann"'
Autor:
Danielle I. Aronowitz, Tracy R. Geoffrion, Sarah Piel, Sarah R. Morton, Jonathan Starr, Richard W. Melchior, Hunter A. Gaudio, Rinat Degani, Nicholas J. Widmann, M. Katie Weeks, Nicolina R. Ranieri, Emilie Benson, Tiffany S. Ko, Daniel J. Licht, Marco Hefti, J. William Gaynor, Todd J. Kilbaugh, Constantine D. Mavroudis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5466 (2024)
Optimal oxygen management during pediatric cardiopulmonary bypass (CPB) is unknown. We previously demonstrated an increase in cortical mitochondrial reactive oxygen species and decreased mitochondrial function after CPB using hyperoxic oxygen managem
Externí odkaz:
https://doaj.org/article/3ac3abee895246b5985bf802bad0cc2c
Autor:
Manvendra Singh, Aleksandra M Kondrashkina, Thomas J Widmann, Jose L Cortes, Vikas Bansal, Jichang Wang, Christine Römer, Marta Garcia-Canadas, Jose L Garcia-Perez, Laurence D Hurst, Zsuzsanna Izsvák
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002162 (2023)
There remains much that we do not understand about the earliest stages of human development. On a gross level, there is evidence for apoptosis, but the nature of the affected cell types is unknown. Perhaps most importantly, the inner cell mass (ICM),
Externí odkaz:
https://doaj.org/article/124c7b6fd472479b998f8d9697af54ad
Akademický článek
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Autor:
Samuel S. Shin, Vanessa M. Mazandi, Andrea L. C. Schneider, Sarah Morton, Jonathan P. Starr, M. Katie Weeks, Nicholas J. Widmann, David H. Jang, Shih-Han Kao, Michael K. Ahlijanian, Todd J. Kilbaugh
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1807 (2023)
Traumatic brain injury (TBI) results in the generation of tau. As hyperphosphorylated tau (p-tau) is one of the major consequences of TBI, targeting p-tau in TBI may lead to the development of new therapy. Twenty-five pigs underwent a controlled cort
Externí odkaz:
https://doaj.org/article/f4d54294249a4783acbd41a60ec0601f
Autor:
Breazeale, Daniel
Publikováno v:
The Review of Metaphysics, 1983 Dec 01. 37(2), 434-436.
Externí odkaz:
https://www.jstor.org/stable/20128041
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Adhesion to the extracellular matrix (ECM) is required for normal epithelial cell survival. Disruption of this interaction leads to a specific type of apoptosis known as anoikis. Yet, there are physiological and pathological situations in which cells
Externí odkaz:
https://doaj.org/article/df1e0f690b8049c2921b8115c51ff9a5
Autor:
Javier Valverde-Pozo, Jose Manuel Paredes, Maria Eugenia García-Rubiño, Thomas J. Widmann, Carmen Griñan-Lison, Silvia Lobon-Moles, Juan Antonio Marchal, Jose Maria Alvarez-Pez, Eva Maria Talavera
Publikováno v:
Chemosensors, Vol 11, Iss 2, p 145 (2023)
Melanoma is a type of highly malignant and metastatic skin cancer. In situ molecular imaging of endogenous levels of the melanoma biomarker tyrosinase (TYR) may decrease the likelihood of mortality. In this study, we proposed the weakly fluorescent p
Externí odkaz:
https://doaj.org/article/2eabe1cab7c3440dae96467ea361e8b1
Autor:
Gisele V. Baracho, Nihan Kara, Stephanie Rigaud, Evelyn Lo, Stephanie J. Widmann, Aaron J. Tyznik
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101069- (2022)
Summary: Cytotoxic T lymphocytes and natural killer (NK) cells are key effector cells in immune defenses against intracellular pathogens and cancer. In human blood, effector T and NK cytotoxic cells comprise a diverse and relatively rare group of cel
Externí odkaz:
https://doaj.org/article/f277248faba14c1fb8f13b03a4e4bfa4
Autor:
Xiaoshan Shi, Gisele V. Baracho, Woodrow E. Lomas, III, Stephanie J. Widmann, Aaron J. Tyznik
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100893- (2021)
Summary: The dual interrogation of the transcriptome and proteome with single-cell resolution provides exquisite insights into immune mechanisms in health and disease. Here, we describe a cutting-edge protocol wherein we combine Cellular Indexing of
Externí odkaz:
https://doaj.org/article/a0c6a615e0444b528e8556f46de70088
Autor:
Javier Valverde-Pozo, Jose M. Paredes, Thomas J. Widmann, Carmen Griñan-Lison, Giada Ceccarelli, Antimo Gioiello, M. Eugenia Garcia-Rubiño, Juan A. Marchal, Jose M. Alvarez-Pez, Eva M. Talavera
Publikováno v:
ACS Sensors. 8:1064-1075
DPP IV, otherwise known as CD26 lymphocyte T surface antigen, is a transmembrane glycoprotein also found in circulation in the blood. It plays an important role in several processes like glucose metabolism and T-cell stimulation. Moreover, it is over