Zobrazeno 1 - 10
of 1 250
pro vyhledávání: '"J Waxman"'
Publikováno v:
eLife, Vol 12 (2023)
Sex differences in plasma growth hormone (GH) profiles, pulsatile in males and persistent in females, regulate sex differences in hepatic STAT5 activation linked to sex differences in gene expression and liver disease susceptibility, but little is un
Externí odkaz:
https://doaj.org/article/685a18209ee34a928afdad8a23570443
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Spatial Frequency Domain Imaging (SFDI) can provide longitudinal, label-free, and widefield hemodynamic and scattering measurements of murine tumors in vivo. Our previous work has shown that the reduced scattering coefficient (μ′s) at 800
Externí odkaz:
https://doaj.org/article/18fcc7f6f3744fc686f14c64a248e071
Autor:
Syeda Tabassum, Anup Tank, Fay Wang, Kavon Karrobi, Cameron Vergato, Irving J. Bigio, David J. Waxman, Darren Roblyer
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 3, Pp 294-303 (2021)
Monitoring of the in vivo tumor state to track therapeutic response in real time may help to evaluate new drug candidates, maximize treatment efficacy, and reduce the burden of overtreatment. Current preclinical tumor imaging methods have largely foc
Externí odkaz:
https://doaj.org/article/7fa8e09717924d47971fc57b42e9d0d1
Autor:
Christine N. Goldfarb, David J. Waxman
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-28 (2021)
Abstract Background While nuclear transcription and RNA processing and localization are well established for protein coding genes (PCGs), these processes are poorly understood for long non-coding (lnc)RNAs. Here, we characterize global patterns of tr
Externí odkaz:
https://doaj.org/article/b8387c378282402898f47042787eceeb
Publikováno v:
Patient Safety in Surgery, Vol 15, Iss 1, Pp 1-9 (2021)
Abstract Background Recommendations are for nearly universal venous thromboembolism (VTE) prophylaxis in critically ill hospitalized patients because of their well-recognized risks. In those intensive care units (ICUs) where patient care is more unif
Externí odkaz:
https://doaj.org/article/52c3c3f6a94f4e5fb83a49634b0c6826
Autor:
Chad N. Brocker, Donghwan Kim, Tisha Melia, Kritika Karri, Thomas J. Velenosi, Shogo Takahashi, Daisuke Aibara, Jessica A. Bonzo, Moshe Levi, David J. Waxman, Frank J. Gonzalez
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
PPAR-alpha is a ligand responsive transcription factor that mediates energy metabolism during fasting in the liver. Here the authors show that Gm15441 is a PPAR-alpha dependent lncRNA that prevents the expression of its antisense transcript, thioredo
Externí odkaz:
https://doaj.org/article/1d2f0c30e94149ecae45a0d442e06efa
Autor:
Bryan J. Matthews, David J. Waxman
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-25 (2020)
Abstract Several thousand sex-differential distal enhancers have been identified in mouse liver; however, their links to sex-biased genes and the impact of any sex-differences in nuclear organization and chromatin interactions are unknown. To address
Externí odkaz:
https://doaj.org/article/5effa45b0e4541799fd6566de1a84bf5
Publikováno v:
PLoS Genetics, Vol 17, Iss 11, p e1009588 (2021)
Sex differences in gene expression are widespread in the liver, where many autosomal factors act in tandem with growth hormone signaling to regulate individual variability of sex differences in liver metabolism and disease. Here, we compare hepatic t
Externí odkaz:
https://doaj.org/article/fc82d4d06c4b47cc84c4ba1e509db9be
Autor:
Graeme R. Williams, MD, MBA, Anish A. Butala, MD, Shwetha H. Manjunath, MD, Russell J.L. Maxwell, MD, Emily J. Anstadt, MD, PhD, Adam J. Waxman, MD, Joshua A. Jones, MD, John P. Plastaras, MD, PhD, Ima Paydar, MD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 4, Pp 100720- (2021)
Purpose: Myeloma lesions of the head can present with central nervous system (CNS) involvement (leptomeningeal disease or brain metastasis), cranial neuropathy (CN), or impending neurologic involvement (INI). We analyzed response and survival after p
Externí odkaz:
https://doaj.org/article/e2e2bbcdfa2441f48a165074dbc85826
Autor:
Kiran A. Faryar, Heather Henderson, Jason W. Wilson, Bhakti Hansoti, Larissa S. May, Elissa M. Schechter‐Perkins, Michael J. Waxman, Richard E. Rothman, Jason S. Haukoos, Michael S. Lyons, EMTIDE (Emergency Medicine Transmissible Infectious Diseases and Epidemics), Society for Academic Emergency Medicine
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 2, Iss 3, Pp n/a-n/a (2021)
Abstract Emergency departments (EDs) have played a major role in the science and practice of HIV population screening. After decades of experience, EDs have demonstrated the capacity to provide testing and linkage to care to large volumes of patients
Externí odkaz:
https://doaj.org/article/bb3c809c9cc4478e83fe62fc2bac37b4