Zobrazeno 1 - 10
of 54
pro vyhledávání: '"J Wantyghem"'
Autor:
Michèle Aubery, Jacqueline Font, J. Wantyghem, Mireille Giner, M. P. Muriel, F. Braut-Boucher, J. Pichon
Publikováno v:
Toxicology in Vitro. 11:601-611
To assess the molecular and cellular events that occur in the skin during biological and pharmaco-toxicological processes, we developed different in vitro models. Two major systems are described: (1) relatively simple ones such as normal human kerati
Publikováno v:
Biochemical Journal. 311:629-636
Lymphocytes undergo activation in response to antigens, cytokines, lectins and antibodies interacting with specific cell-surface molecules or through substances influencing signal transduction pathways. This study shows that human T- and B-cells stim
Autor:
D, Aït-Azzouzene, S, Caucheteux, F, Tchang, J, Wantyghem, R, Moutier, A, Langkopf, M C, Gendron, C, Kanellopoulos-Langevin
Publikováno v:
Biology of reproduction. 65(2)
We have produced transgenic mice using the mouse placental lactogen type II promoter to force and restrict the expression of the mouse major histocompatibility complex (MHC) class I molecule, H-2K(b), to the placenta. We show that the transgenic MHC
Publikováno v:
Experimental cell research. 221(1)
We previously showed that ricin, a toxin commonly used in the construction of immunotoxins, was more toxic to undifferentiated than to differentiated HT-29 tumoral cells. This results from differences in the intracellular routings of the toxin. As th
Autor:
J, Wantyghem, G, Sabeur
Publikováno v:
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. 312(13)
Codon usage in the coding region of mature lectins has been examined for 11 plant species (8 leguminoseae, 1 euphorbiaceae, 2 gramineae). The different legume lectins exhibit nearly the same codon usage pattern whereas the choice for the silent posit
Publikováno v:
Canadian Journal of Biochemistry and Cell Biology. 62:203-208
Formaldehyde treatment of Ricinus communis agglutinin, a nonmitogenic toxic 120 000 molecular weight (MW) lectin, yielded two distinct protein fractions: one was heterogeneous and contained high molecular weight lectin polymers (> 120 000), and the o
Publikováno v:
Biochemical Journal. 237:483-489
Two lectins, RPA 1 and RPA 3, were purified from Robinia pseudoacacia seeds. These two lectins differ in their physicochemical and biological properties. By analytical ultracentrifugation the Mr values of RPA 1 and RPA 3 were estimated to be 59,000 a
Publikováno v:
Journal of Chromatography A. 172:399-403
Publikováno v:
Molecular and Cellular Biology. 3:1138-1145
Rat 3T3 cells transformed by simian virus 40 were injected into rats to examine their capacity to develop into tumors. Both large T-dependent (N) transformants and large T-independent (A) transformants were used. All the transformed cell lines contai
Publikováno v:
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles. 286(4)
Glycoproteins of the lymphocyte surface are involved in many membrane mediated events. Their specific carbohydrate determinants might interact with lectins. Purification of macromolecules released from normal human lymphocytes by trypsin was performe