Brain matters: unveiling the distinct contributions of region, age, and sex to glia diversity and CNS function

Autor: Luise A. Seeker, Nadine Bestard-Cuche, Sarah Jäkel, Nina-Lydia Kazakou, Sunniva M. K. Bøstrand, Laura J. Wagstaff, Justyna Cholewa-Waclaw, Alastair M. Kilpatrick, David Van Bruggen, Mukund Kabbe, Fabio Baldivia Pohl, Zahra Moslehi, Neil C. Henderson, Catalina A. Vallejos, Gioele La Manno, Goncalo Castelo-Branco, Anna Williams

Publikováno v: Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-23 (2023)

Abstract The myelinated white matter tracts of the central nervous system (CNS) are essential for fast transmission of electrical impulses and are often differentially affected in human neurodegenerative diseases across CNS region, age and sex. We hy

Externí odkaz: https://doaj.org/article/f29980c47b3d48f6bf0dc467b3b6f292

Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun

Autor: Laura J Wagstaff, Jose A Gomez-Sanchez, Shaline V Fazal, Georg W Otto, Alastair M Kilpatrick, Kirolos Michael, Liam YN Wong, Ki H Ma, Mark Turmaine, John Svaren, Tessa Gordon, Peter Arthur-Farraj, Sergio Velasco-Aviles, Hugo Cabedo, Cristina Benito, Rhona Mirsky, Kristjan R Jessen

Publikováno v: eLife, Vol 10 (2021)

After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during chronic denervation that results from slow axon g

Externí odkaz: https://doaj.org/article/71cf5cebbc4d40f8b6b3a29c0b196abc

A Generic Taxonomic Synopsis of thePleurophyllumClade (Asteraceae: Astereae: Celmisiinae) with the Recognition of the New Zealand Endemic New GenusMacrolearia

Autor: Patricio Saldivia, Steven J. Wagstaff, Ilse Breitwieser, David A. Orlovich, Janice M. Lord

Publikováno v: Systematic Botany. 47:607-634

—ThePleurophyllumclade is one of two main clades within subtribe Celmisiinae (Astereae) and includes 10 species almost entirely restricted to New Zealand (one species also occurs in the Australian Macquarie Islands), with seven of them confined to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60898ebf21d51e908973f99dd09d0798
https://doi.org/10.1600/036364422x16512564801722

A reverse genetics and genomics approach to gene paralog function and disease: Myokymia and the juxtaparanode

Autor: Dana Marafi, Nina Kozar, Ruizhi Duan, Stephen Bradley, Kenji Yokochi, Fuad Al Mutairi, Nebal Waill Saadi, Sandra Whalen, Theresa Brunet, Urania Kotzaeridou, Daniela Choukair, Boris Keren, Caroline Nava, Mitsuhiro Kato, Hiroshi Arai, Tawfiq Froukh, Eissa Ali Faqeih, Ali M. AlAsmari, Mohammed M. Saleh, Filippo Pinto e Vairo, Pavel N. Pichurin, Eric W. Klee, Christopher T. Schmitz, Christopher M. Grochowski, Tadahiro Mitani, Isabella Herman, Daniel G. Calame, Jawid M. Fatih, Haowei Du, Zeynep Coban-Akdemir, Davut Pehlivan, Shalini N. Jhangiani, Richard A. Gibbs, Satoko Miyatake, Naomichi Matsumoto, Laura J. Wagstaff, Jennifer E. Posey, James R. Lupski, Dies Meijer, Matias Wagner

Publikováno v: Am J Hum Genet
Marafi, D, Kozar, N, Duan, R, Bradley, S, Yokochi, K, Al Mutairi, F, Waill Saadi, N, Whalen, S, Brune, T, Kotzaeridou, U, Choukair, D, Keren, B, Nava, C, Kato, M, Arai, H, Froukh, T, Faqeih, E A, AlAsmari, A M, Saleh, M M, Vairo, F P E, Pichurin, P N, Klee, E W, Schmitz, C T, Grochowski, C M, Mitani, T, Herman, I, Calame, D, Faith, J M, Du, H, Coban-Akdemir, Z, Pehlivan, D, Jhangiani, S N, Gibbs, R A, Miyatake, S, Matsumoto, N, Wagstaff, L J, Posey, J E, Lupski, J R, Meijer, D & Wagner, M 2022, ' A reverse Genetics and Genomics Approach to Gene Paralog Function and Disease : Myokymia and The Juxtaparanode ', American Journal of Human Genetics, vol. 109 . https://doi.org/10.1016/j.ajhg.2022.07.006
Am. J. Hum. Genet. 109, 1713-1723 (2022)

The leucine-rich glioma-inactivated (LGI) family consists of four highly conserved paralogous genes, LGI1-4, that are highly expressed in mammalian central and/or peripheral nervous systems. LGI1 antibodies are detected in subjects with autoimmune li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37caee5177da2f52c5e1a52549031f22
https://pubmed.ncbi.nlm.nih.gov/35948005

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