Zobrazeno 1 - 10
of 904
pro vyhledávání: '"J WADDINGTON"'
Autor:
Sheng Shen, Neha Koonjoo, Thomas Boele, Jiaqi Lu, David E. J. Waddington, Marie Zhang, Matthew S. Rosen
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Superparamagnetic iron oxide nanoparticles (SPIONs) are characterized by their exceptional susceptibility and relaxivity at ultra-low field (ULF) regimes, make them a promising contrast agent (CA) for ULF MRI. Despite their distinct advantag
Externí odkaz:
https://doaj.org/article/7294161dd5ae47b190c2f094b9599dbd
Autor:
James Grover, Paul Liu, Bin Dong, Shanshan Shan, Brendan Whelan, Paul Keall, David E. J. Waddington
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background Magnetic resonance imaging (MRI) offers superb non-invasive, soft tissue imaging of the human body. However, extensive data sampling requirements severely restrict the spatiotemporal resolution achievable with MRI. This limits the
Externí odkaz:
https://doaj.org/article/3ae5da85b637451d8ce8e9afefe31e93
Autor:
Caterina Brighi, David E. J. Waddington, Paul J. Keall, Jeremy Booth, Kieran O’Brien, Shona Silvester, Jonathon Parkinson, Marco Mueller, Jackie Yim, Dale L. Bailey, Michael Back, James Drummond
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundGlioblastoma (GBM) is the most aggressive type of brain cancer, with a 5-year survival rate of ~5% and most tumours recurring locally within months of first-line treatment. Hypoxia is associated with worse clinical outcomes in GBM, as it le
Externí odkaz:
https://doaj.org/article/5edcdad8f4af4d379976474a7c4ef04a
Publikováno v:
Frontiers in Dental Medicine, Vol 4 (2023)
IntroductionBone has a high capacity for repair, but for patients with uncontrolled type 2 diabetes mellitus (T2DM), the associated hyperglycemia can significantly delay osteogenic processes. These patients respond poorly to fracture repair and bone
Externí odkaz:
https://doaj.org/article/2633520d04654f70a919d9192a4afba7
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-19 (2021)
Abstract Background Dental pulp stem cells (DPSCs) are increasingly being advocated as viable cell sources for regenerative medicine-based therapies. However, significant heterogeneity in DPSC expansion and multi-potency capabilities are well-establi
Externí odkaz:
https://doaj.org/article/962248b885f947059fabb6c3dc01b8ff
Publikováno v:
Frontiers in Dental Medicine, Vol 3 (2022)
Mesenchymal stromal cells (MSCs) have long been the focus for regenerative medicine and the restoration of damaged or aging cells throughout the body. However, the efficacy of MSCs in cell-based therapy still remains unpredictable and carries with it
Externí odkaz:
https://doaj.org/article/3ca5d9e1c0d24a32a4d4361f0aeaf39e
Autor:
Zi Y. Kok, Nadia Y. A. Alaidaroos, Amr Alraies, John S. Colombo, Lindsay C. Davies, Rachel J. Waddington, Alastair J. Sloan, Ryan Moseley
Publikováno v:
Stem Cells International, Vol 2022 (2022)
Human dental pulp stem/stromal cells (hDPSCs) derived from the permanent secondary dentition are recognised to possess certain advantageous traits, which support their potential use as a viable source of mesenchymal stem/stromal cells (MSCs) for rege
Externí odkaz:
https://doaj.org/article/6286b3f5f0df4f84bbef2dc42bff4c8c
Publikováno v:
BMC Molecular and Cell Biology, Vol 20, Iss 1, Pp 1-18 (2019)
Abstract Background Mesenchymal stromal cells in the endosteal niche lining compact bone (CB-MSCs) represent a heterogeneous population, all of which contribute to bone repair and remodelling. Hyperglycaemia associated with type 2 diabetes mellitus (
Externí odkaz:
https://doaj.org/article/edecab683be541239a2bb096fbccc1bd
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Mobilization of naïve bone marrow mesenchymal stromal cells (BMSCs) is crucial to desired bone regeneration in both orthopedic and dental contexts. In such conditions, mesenchymal progenitor cell populations from human exfoliated deciduous teeth (SH
Externí odkaz:
https://doaj.org/article/c22d0c75f95845d9b43afdf1a482f6fa
Autor:
David E. J. Waddington, Mathieu Sarracanie, Huiliang Zhang, Najat Salameh, David R. Glenn, Ewa Rej, Torsten Gaebel, Thomas Boele, Ronald L. Walsworth, David J. Reilly, Matthew S. Rosen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Hyperpolarized magnetic resonance imaging can enhance imaging contrast by orders of magnitude, but applications are limited by the thermal relaxation of hyperpolarized states. Here, Waddingtonet al. demonstrate the on-demand hyperpolarization of hydr
Externí odkaz:
https://doaj.org/article/b51b984e0c19410db97859d79257ccb7