Výsledky vyhledávání

NF-κB is a critical mediator of BRCA1-induced chemoresistance

Autor: Julia J. Gorski, Paul B. Mullan, Mary T. Harte, J W Purcell, Eliana M. Barros, P M Burn, Kienan I. Savage, Neil D. Perkins, Richard D. Kennedy, D. P. Harkin, C McFarlane

Publikováno v: Oncogene

BRCA1 mediates resistance to apoptosis in response to DNA-damaging agents, causing BRCA1 wild-type tumours to be significantly more resistant to DNA damage than their mutant counterparts. In this study, we demonstrate that following treatment with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb393171aa9127c2f9b416c8a19c41b6
https://pubmed.ncbi.nlm.nih.gov/23435429

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání