NF-κB is a critical mediator of BRCA1-induced chemoresistance

Autor: Julia J. Gorski, Paul B. Mullan, Mary T. Harte, J W Purcell, Eliana M. Barros, P M Burn, Kienan I. Savage, Neil D. Perkins, Richard D. Kennedy, D. P. Harkin, C McFarlane

Publikováno v: Oncogene

BRCA1 mediates resistance to apoptosis in response to DNA-damaging agents, causing BRCA1 wild-type tumours to be significantly more resistant to DNA damage than their mutant counterparts. In this study, we demonstrate that following treatment with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb393171aa9127c2f9b416c8a19c41b6
https://pubmed.ncbi.nlm.nih.gov/23435429

Skull Base Repair following Resection of Vestibular Schwannoma: A Systematic Review (Part 1: The Retrosigmoid Approach).

Autor: Starup-Hansen, Joachim, Williams, Simon C., Valetopoulou, Alexandra, Khan, Danyal Z., Horsfall, Hugo Layard, Moudgil-Joshi, Jigishaa, Burton, Oliver, Kanona, Hala, Saeed, Shakeel R., Muirhead, William, Marcus, Hani J., Grover, Patrick

Publikováno v: Journal of Neurological Surgery. Part B. Skull Base; 2024 Supplement 1, Vol. 85 Issue 8, pe117-e130, 14p

Design, Synthesis, and Evaluation of Biological Activity of Ferrocene‐Ispinesib Hybrids: Impact of a Ferrocenyl Group on the Antiproliferative and Kinesin Spindle Protein Inhibitory Activity.

Autor: Kowalczyk, Karolina¹ (AUTHOR), Błauż, Andrzej² (AUTHOR), Moscoh Ayine‐Tora, Daniel³ (AUTHOR), Hartinger, Christian G.⁴ (AUTHOR), Rychlik, Błażej² (AUTHOR), Plażuk, Damian¹ (AUTHOR) damian.plazuk@chemia.uni.lodz.pl

Publikováno v: Chemistry - A European Journal. 9/1/2023, Vol. 29 Issue 49, p1-10. 10p.

Synthese und Biologische Untersuchungen von C(13)/C(13′)‐Bis(desmethyl)disorazol Z**.

Autor: Bold, Christian Paul¹ (AUTHOR), Lucena‐Agell, Daniel² (AUTHOR), Oliva, María Ángela² (AUTHOR), Díaz, José Fernando² (AUTHOR), Altmann, Karl‐Heinz¹ (AUTHOR) karl-heinz.altmann@pharma.ethz.ch

Publikováno v: Angewandte Chemie. 1/26/2023, Vol. 135 Issue 5, p1-9. 9p.

Atomically Precise Metal-Metal Oxide Interface in Polyoxometalate-Noble Metal Hybrid Clusters.

Autor: Wang HN; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, P. R. China., Meng X; School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, P. R. China., Cao Y; School of Chemistry, National and Local Joint Engineering Research Center of MPTES in High Energy and Safety LIBs, Engineering Research Center of MTEES (Ministry of Education), Key Lab. of ETESPG(GHEI), South China Normal University, Guangzhou, 510006, P. R. China., Li SL; School of Chemistry, National and Local Joint Engineering Research Center of MPTES in High Energy and Safety LIBs, Engineering Research Center of MTEES (Ministry of Education), Key Lab. of ETESPG(GHEI), South China Normal University, Guangzhou, 510006, P. R. China., Lan YQ; School of Chemistry, National and Local Joint Engineering Research Center of MPTES in High Energy and Safety LIBs, Engineering Research Center of MTEES (Ministry of Education), Key Lab. of ETESPG(GHEI), South China Normal University, Guangzhou, 510006, P. R. China.

Publikováno v: Small (Weinheim an der Bergstrasse, Germany) [Small] 2024 Nov 20, pp. e2408884. Date of Electronic Publication: 2024 Nov 20.