Výsledky vyhledávání

Safety, immunogenicity, and efficacy in monkeys and humans of invasive Escherichia coli K-12 hybrid vaccine candidates expressing Shigella flexneri 2a somatic antigen

Autor: Myron M. Levine, Karen L. Kotloff, D A Herrington, L. Van de Verg, Samuel B. Formal, P J Snoy, J P Cogan, J W Newland, T L Hale, J C Sadoff

Publikováno v: Infection and immunity. 60(6)

A live, oral Shigella vaccine, constructed by transfer of the 140-MDa invasiveness plasmid from Shigella flexneri 5 and the chromosomal genes encoding the group- and type-specific O antigen of S. flexneri 2a to Escherichia coli K-12, was tested in hu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa9f290a49be6c9fefd67b239a204c1
https://pubmed.ncbi.nlm.nih.gov/1587589

Zobrazit plný text záznamu

DNA probes for Shiga-like toxins I and II and for toxin-converting bacteriophages

Autor: J W Newland, R J Neill

Publikováno v: Journal of Clinical Microbiology. 26:1292-1297

A set of DNA probes has been developed to study the genes for Shiga-like toxins (SLT) and the bacteriophage from which these toxin genes were isolated. Under stringent conditions of hybridization (80 to 90% homology), these probes detect strains cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861f1709589ab7c0619fb734fd73b8e5
https://doi.org/10.1128/jcm.26.7.1292-1297.1988

Zobrazit plný text záznamu

Determination by DNA hybridization of Shiga-like-toxin-producing Escherichia coli in children with diarrhea in Thailand

Autor: Jitvimol Seriwatana, Udom Lexomboon, J E Brown, V Vanapruks, J W Newland, David N. Taylor, P Echeverria, R N Neill

Publikováno v: Journal of Clinical Microbiology. 27:291-294

Specific DNA probes were used to identify Shiga-like-toxin (SLT) I- and II-producing Escherichia coli from children less than 5 years of age with bloody diarrhea, in infants with diarrhea, and in controls of the same age without diarrhea in Thailand.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794dea8b473d8414c9f4d8de5cdbc1ed
https://doi.org/10.1128/jcm.27.2.291-294.1989

Zobrazit plný text záznamu

Serology and plasmid carriage in Vibrio cholerae

Autor: L A McNicol, M J Voll, J W Newland

Publikováno v: Canadian Journal of Microbiology. 30:1149-1156

Vibrio cholerae strains of the 01 serovar, isolated from both clinical and environmental sources, had a much lower frequency of plasmid carriage (2/112 = 2%) than clinical and environmental non-01 serovar isolates (46/187 = 25%). The cryptic plasmids

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b3019b32d06cef7a45a91093b4b7c7
https://doi.org/10.1139/m84-180

Zobrazit plný text záznamu

Cloning of extracellular DNase and construction of a DNase-negative strain of Vibrio cholerae

Autor: J Foulds, Randall K. Holmes, B A Green, J W Newland

Publikováno v: Infection and immunity. 47(3)

The structural gene xds for extracellular DNase of Vibrio cholerae was cloned and inactivated by insertion of the transposon Tn5. The inactivated gene was introduced into the chromosome of V. cholerae by recombination to construct an extracellular DN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c00f4afac4b9582242ea68216bb307e8
https://pubmed.ncbi.nlm.nih.gov/2982738

Zobrazit plný text záznamu

Mapping of chromosomal genes that determine the El Tor biotype in Vibrio cholerae

Autor: J W Newland, B A Green, Randall K. Holmes

The El Tor biotype of Vibrio cholerae has several characteristics that differentiate it from the classical biotype of V. cholerae. Among these are production of soluble hemolysin(s), a cell-associated hemagglutinin for chicken erythrocytes, resistanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eada06dc73ba9405cf56271091472886
https://europepmc.org/articles/PMC264387/

Zobrazit plný text záznamu

Isolation and characterization of small plasmids in strains of Vibrio parahaemolyticus

Autor: L S, Isaki, R A, Bever, J W, Newland, M J, Voll

Publikováno v: Journal of diarrhoeal diseases research. 1(2)

Vibrio parahaemolyticus strains isolated from patients and foods incriminated in 4 incidents of gastroenteritis, as well as a strain from a healty carrier were analyzed for plasmids. Large plasmids were found in a Kanagawa phenomenon positive (KP+) p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5621e3fc98c45b2fb639bd331cf46a7a
https://pubmed.ncbi.nlm.nih.gov/6094652

Zobrazit plný text záznamu

DNA probes to identify Shiga-like toxin I- and II-producing enteric bacterial pathogens isolated from patients with diarrhea in Thailand

Autor: Jitvimol Seriwatana, P Echeverria, J. E. Brown, Orasa Suthienkul, David N. Taylor, J W Newland

Publikováno v: Journal of Clinical Microbiology. 26:1614-1615

When Shigella species, Escherichia coli, and five other bacterial enteric pathogens isolated from children with diarrhea in Thailand were tested for hybridization under stringent conditions with probes for Shiga-like toxins I and II, only 30 Shigella

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5a96b9727667b92ca71ce3ee498af8
https://doi.org/10.1128/jcm.26.8.1614-1615.1988

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání