Zobrazeno 1 - 10
of 30
pro vyhledávání: '"J W Kozarich"'
Publikováno v:
Biochemistry. 34:2788-2797
On the basis of the available high-resolution structures of mandelate racemase (MR) from Pseudomonas putida [Landro, J. A., Gerlt, J. A., Kozarich, J. W., Koo, C. W., Shah, V. J., Kenyon, G. L., Neidhart, D. J., Fujita, J.,Petsko, G. A. (1994) Bioche
Publikováno v:
The Journal of biological chemistry. 272(2)
Nitric-oxide synthases (NOS, EC 1.14.13.39) are heme-containing enzymes that catalyze the formation of nitric oxide from L-Arg. General cytochrome P-450 inhibitors and cytochrome P-450 isoform-selective substrates and inhibitors were used to characte
Autor:
S R, Doctrow, S M, Abelleira, L A, Curry, R, Heller-Harrison, J W, Kozarich, B, Malfroy, L A, McCarroll, K G, Morgan, A R, Morrow, G F, Musso
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(1)
The vasoactive peptide bradykinin is believed to cause increased vascular permeability by the activation of B2 receptors on the vascular endothelium. A bradykinin analog, H-Arg-Pro-Hyp-Gly-Thi-Ser-Pro-4-Me-Tyr(psi CH2NH)-Arg-OH (RMP-7), was designed
Publikováno v:
Journal of bacteriology. 176(6)
3-Carboxy-cis,cis-muconate lactonizing enzyme (CMLE; EC 5.5.1.5) from Neurospora crassa catalyzes the reversible gamma-lactonization of 3-carboxy-cis,cis-muconate by a syn-1,2 addition-elimination reaction. The stereochemical and regiochemical course
Publikováno v:
Journal of Biological Chemistry. 258:4694-4697
Poly(dA.dU), which is specifically tritiated at the 1'-, 2'- (ribo configuration), 3'-, or 4'-position of deoxyuridine, has been synthesized and the fate of the tritium has been determined upon degradation of the polymer by bleomycin, Fe(II), and O2.
Autor:
J W Kozarich, J L Strominger
Publikováno v:
Journal of Biological Chemistry. 253:1272-1278
Staphylococcus aureus H membranes were found to contain four major binding components: Mr = 115,000; Mr = 100,000 doublet; and Mr = 46,000. The low molecular weight protein bound penicillin reversibly and was purified by prebinding membranes with pen
Publikováno v:
Journal of Biological Chemistry. 252:2934-2939
The kinetics of hydrolysis and transpeptidation of the synthetic substrate diacetyl-L-lysyl-D-alanyl-D-alanine and of the natural substrate UDP-acetylmuramyl pentapeptide and related compounds catalyzed by the D-alanine carboxypeptidases of Bacillus
Autor:
J W Kozarich, J L Deegan
Publikováno v:
Journal of Biological Chemistry. 254:9345-9348
Studies on the inhibition of translation by methylglyoxal of capped and chemically decapped globin mRNAs in the rabbit reciculocyte system strongly suggest that it is cap-dependent. Concentrations of methylglyoxal (0.2 mM), which effected substantial
Publikováno v:
Journal of Biological Chemistry. 252:7525-7529
The hydroxylaminolysis of the penicilloyl moiety from [14C]penicillin G binding component (PBC) complexes of the Bacillus subtilis D-alanine carboxypeptidase and of the mixture of PBC's of Staphylococcus aureus was inhibited by denaturation of the co
Publikováno v:
Journal of Biological Chemistry. 258:6823-6826
The paramagnetic effects of Mn2+ . glyoxalase I on the 13C relaxation rates of the reaction product, S-(D-lactoyl)glutathione, separately enriched in the lactoyl carbonyl (C-1) and hydroxymethylene (C-2) carbons, have been measured at 62.8 MHz. The 1