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DRD4 Interacts with TGF-β Receptors to Drive Colorectal Cancer Metastasis Independently of Dopamine Signaling Pathway.

Autor: Zhou Y; Department of Pathology and Run Run Shaw Hospital, Research Unit of Intelligence Classifification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310058, China., Tang J; Department of Pathology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310058, China., Weng M; Department of Pathology, the First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310006, China., Zhang H; Department of Pathology, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310058, China., Lai M; Department of Pathology and Run Run Shaw Hospital, Research Unit of Intelligence Classifification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310058, China.

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Dec 16, pp. e2413953. Date of Electronic Publication: 2024 Dec 16.

Phosphorylation of DARPP-32 and protein phosphatase inhibitor-1 in rat choroid plexus: regulation by factors other than dopamine

Autor: J. W. Kebabian, Paul Greengard, Gretchen L. Snyder, J. A. Nathanson, Jean-Antoine Girault, Andrew J. Czernik, J.-Y. C. Chen

Publikováno v: The Journal of Neuroscience. 12:3071-3083

The molecular mechanisms underlying regulation of fluid production by secretory epithelia such as the choroid plexus are poorly understood. Two cAMP-regulated inhibitors of protein phosphatase-1, inhibitor-1 (I1) and a dopamine- and cAMP-regulated ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51c17ca22be139c982938fb669792d68
https://doi.org/10.1523/jneurosci.12-08-03071.1992

A68930: A Potent and Specific Agonist for the D-1 Dopamine Receptor

Autor: K. Asin, R. G. MacKenzie, R. Schoenleber, M. DeNinno, J. F. McKelvy, C. Briggs, D. R. Britton, J. W. Kebabian

Publikováno v: American Journal of Hypertension. 3:40S-42S

A68930 (5,6-dihydroxy-3-phenyl-1-aminomethyl-isochroman) is a potent (EC50 = 2.5 nmol/L) partial agonist at the D-1 dopamine receptor. In contrast, A68930 is a much weaker agonist (EC50 = 3,920 nmol/L) at the D-2 dopamine receptor. The orientation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e42363028cd68cbfb9680abcc3714b
https://doi.org/10.1093/ajh/3.6.40s

Differential effect of selective D-1 and D-2 dopamine receptor agonists on levodopa-induced dyskinesia in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine- exposed monkeys

Autor: P, Blanchet, P J, Bédard, D R, Britton, J W, Kebabian

Publikováno v: The Journal of pharmacology and experimental therapeutics. 267(1)

The motor effects of selective D-1 dopamine receptor stimulation in Parkinson's disease have been explored in a limited number of studies with partial D-1 agonists only and the results were unsatisfactory. Four 1-methyl-4-phenyl-1,2,3,6-tetrahydropyr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::160904ba1a75645623ceb0bbfce79267
https://pubmed.ncbi.nlm.nih.gov/7901395