Zobrazeno 1 - 10
of 67
pro vyhledávání: '"J W Fletcher"'
Publikováno v:
Trends in Molecular Medicine. 26:170-184
The last decade has seen rapid advances in the understanding of the central role of glucocorticoids in preparing the fetus for life after birth. However, relative to other organ systems, maturation by glucocorticoids of the fetal cardiovascular syste
Publikováno v:
Pediatric Research. 69:118-122
This study tested the hypothesis that the sexually dimorphic adrenocortical response to stress is already established before birth. Chronically instrumented late gestation pregnant sheep carrying 16 male and 15 female age-matched singleton fetuses we
Autor:
Abigail L. Fowden, Andrew J. W. Fletcher, William R. Ford, Dino A. Giussani, Alison J. Forhead, Peter W. Nathanielsz
Publikováno v:
The Journal of Physiology. 562:493-505
Structural and functional maturation of a number of fetal organs and physiological systems occurs in the immediate period prior to term, in association with the prepartum increase in fetal plasma cortisol concentration. At present, little is known ab
Publikováno v:
The Journal of Physiology. 557:1021-1032
Twin fetuses experience much higher rates of perinatal mortality/morbidity than age- and weight-matched singletons. Across species, the prepartum increase in fetal plasma cortisol is responsible for maturing a number of systems in preparation for bir
Publikováno v:
The Journal of Physiology. 547:283-291
We tested the hypothesis that enhanced nitric oxide (NO) opposes fetal peripheral vasoconstrictor responses to acute hypoxaemia via actions involving the carotid chemoreflex and the adrenal medulla. The hypothesis was tested in the late gestation ovi
Publikováno v:
Endocrinology. 142:589-598
The present study determined the pituitary-adrenal responses to acute hypoxemia after a period of reversible adverse intrauterine conditions produced by partial compression of the umbilical cord for 3 days in the sheep fetus during late gestation. At
Autor:
Alison J. Forhead, Abigail L. Fowden, Andrew J. W. Fletcher, Mark R Goodfellow, HH McGarrigle, David S. Gardner, Dino A. Giussani
Publikováno v:
Pediatric Research. 47:684-691
Despite the widespread use of antenatal glucocorticoid therapy in obstetric practice, little is known about the effects of synthetic glucocorticoids on the fetal capacity to respond to episodes of acute hypoxemia, such as may occur during labor and d
Publikováno v:
SpaceOps 2012 Conference.
This paper provides an overview of the Laser Communications Relay Demonstration Project (LCRD), a joint project between NASA?s Goddard Space Flight Center (GSFC), the Jet Propulsion Laboratory, California Institute of Technology (JPL), and the Massac
Autor:
David S. Gardner, C. Mark B. Edwards, Abigail L. Fowden, Andrew J. W. Fletcher, Dino A. Giussani
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 291(6)
We tested the hypothesis that fetal cardiovascular responses to hypoxemia change close to full term in relation to the prepartum increase in fetal basal cortisol and investigated, in vivo, the neural and endocrine mechanisms underlying these changes.
Publikováno v:
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 58(1)
Nonadrenergic noncholinergic (NANC) vasodilator mechanisms may contribute to the maintenance of adult pulmonary and systemic vascular tone. However, their actions in the neonatal circulation have not been studied. We aimed to investigate NANC vasorel