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Muramyl dipeptide induces production of hemopoietic growth factors in vivo by a mechanism independent of tumor necrosis factor

Autor: V C Broudy, K Kaushansky, S G Shoemaker, B B Aggarwal, J W Adamson

Publikováno v: The Journal of Immunology. 144:3789-3794

Monocyte products including TNF and IL-1 can stimulate hemopoietic growth factor production in vitro and in vivo. Endotoxin-resistant C3H/HeJ mice have a cellular defect in the regulation of TNF production and provide a model in which to examine the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f2cf6fe1db87ecfafe9b9d7ecd811da
https://doi.org/10.4049/jimmunol.144.10.3789

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Cell dose and speed of engraftment in placental/umbilical cord blood transplantation: graft progenitor cell content is a better predictor than nucleated cell quantity

Autor: A R, Migliaccio, J W, Adamson, C E, Stevens, N L, Dobrila, C M, Carrier, P, Rubinstein

Publikováno v: Blood. 96(8)

There is evidence that the total cellular content of placental cord blood (PCB) grafts is related to the speed of engraftment, though the total nucleated cell (TNC) dose is not a precise predictor of the time of neutrophil or platelet engraftment. It

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::80159e65c09e18ff5fcf9c14ad9bec69
https://pubmed.ncbi.nlm.nih.gov/11023503

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Epoetin alfa: into the new millennium

Autor: J W, Adamson

Publikováno v: Seminars in oncology. 25(3 Suppl 7)

First used successfully to correct the anemia associated with chronic renal failure, epoetin alfa has been shown to be highly effective in many patients with either hematologic or nonhematologic malignancies. Multiple studies have demonstrated effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1dd5ee8385993d704793315503945ca9
https://pubmed.ncbi.nlm.nih.gov/9671336

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The relationship of erythropoietin and iron metabolism to red blood cell production in humans

Autor: J W, Adamson

Publikováno v: Seminars in oncology. 21(2 Suppl 3)

Erythropoietin (EPO) is the primary regulator of day-to-day red blood cell production. Secreted by peritubular capillary lining cells in the kidney, EPO circulates in the plasma to interact with target cells in the bone marrow to maintain or stimulat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ea33bc0e6595bdee40880a19a26c4cb0
https://pubmed.ncbi.nlm.nih.gov/8202725

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Physiologic basis for the pharmacologic use of recombinant human erythropoietin in surgery and cancer treatment

Autor: J W, Adamson, J L, Spivak

Publikováno v: Surgery. 115(1)

Recombinant human erythropoietin (rHuEPO) is approved for the treatment of the anemia of chronic kidney failure and anemia associated with zidovudine therapy of acquired immunodeficiency syndrome. In chronic kidney failure and other conditions such a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::74188b32183a3481428a2c068c8b669b
https://pubmed.ncbi.nlm.nih.gov/8284765

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