Zobrazeno 1 - 10
of 35
pro vyhledávání: '"J W, Regan"'
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 73:533-543
Adrenoceptors can be subdivided into three major types, the α1-, α2-, and β-adrenoceptors. Each of these types can be further subdivided into three subtypes, based on pharmacological characteristics. Molecular cloning techniques have supported thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cf09c50ccce4333b3e094bac37c684
https://doi.org/10.1139/y95-068
https://doi.org/10.1139/y95-068
Publikováno v:
Current eye research. 20(5)
To determine the expression and functional coupling of EP prostanoid receptor subtypes to second messenger pathways in bovine ciliary epithelium.Primary cultures of bovine ciliary epithelial (BCE) cells were established and maintained in culture up t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f81b3f1d5e6df95b5022c7ec12db0da
https://pubmed.ncbi.nlm.nih.gov/10855034
https://pubmed.ncbi.nlm.nih.gov/10855034
Publikováno v:
Molecular pharmacology. 57(2)
Prostaglandin F(2alpha) receptors (FP) are G protein-coupled receptors that bind prostaglandin F(2alpha) (PGF(2alpha)), resulting in the activation of an inositol phosphate (IP) second messenger pathway. Alternative mRNA splicing generates two FP rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0e6bfc85f45176fd4354702a55c494f
https://pubmed.ncbi.nlm.nih.gov/10648645
https://pubmed.ncbi.nlm.nih.gov/10648645
Publikováno v:
Endocrine. 10(2)
Expression of the receptor for prostaglandin F2alpha (PGF2alpha) is decreased in the ovine corpus luteum during regression and increased in early pregnancy. This study was designed to evaluate the influence of progesterone and/or 17beta-estradiol (E2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc9c6dfe302e74d59b7f3fe0081f6257
https://pubmed.ncbi.nlm.nih.gov/10451218
https://pubmed.ncbi.nlm.nih.gov/10451218
Publikováno v:
Investigative ophthalmologyvisual science. 39(2)
Prostaglandin F2 alpha (PGF2 alpha) and analogs, such as latanoprost, are thought to lower intraocular pressure (IOP), primarily by increasing uveoscleral outflow. However, outflow through the trabecular meshwork may be increased as well. The authors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2b6eb2294a0d698ba5ad9dc30b9c318
https://pubmed.ncbi.nlm.nih.gov/9477988
https://pubmed.ncbi.nlm.nih.gov/9477988
Publikováno v:
Investigative ophthalmologyvisual science. 37(12)
For the treatment of glaucoma, alpha-2 adrenergic receptor (alpha 2-AR) agonists are thought to lower intraocular pressure primarily by decreasing aqueous humor production. Effects on the outflow pathways, however, also may occur. To begin to examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c2f2ec13bb85d4cbf742537f5359bc5
https://pubmed.ncbi.nlm.nih.gov/8933759
https://pubmed.ncbi.nlm.nih.gov/8933759
Publikováno v:
Biochemical pharmacology. 51(3)
Functional studies have shown that 6-chloro-9-[(3-methyl-2-butenyl)oxy]-3-methyl-1H-2,3,4,5-tetrahydro-3- benzazepine (SKF 104078) has very low affinity for prejunctional alpha 2-adrenoceptors (alpha 2-AR) in the guinea pig atrium. In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::df4f4977032d5813ea5bf07ddc451440
https://pubmed.ncbi.nlm.nih.gov/8573196
https://pubmed.ncbi.nlm.nih.gov/8573196
Publikováno v:
Investigative ophthalmologyvisual science. 36(13)
To develop antibodies that selectively recognize each of the alpha 2-adrenergic receptor (AR) subtypes and to determine the expression and localization of these subtypes in the anterior segment of the human eye.Recent studies have shown that there ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3dad9a6ba3801f6522b41047347970ce
https://pubmed.ncbi.nlm.nih.gov/7499095
https://pubmed.ncbi.nlm.nih.gov/7499095
Autor:
John E. Donello, Steven W. Andrews, A.M. Bogardus, E. Runde, Alexander B. Kharlamb, D.F. Woodward, J. W. Regan, J.A. Burke, D. W. Gil, Kristen L. Pierce, Karen M. Kedzie, C.E. Fairbairn
Publikováno v:
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 11(3)
The cloning of the genes that encode for prostaglandin (PG) receptors has resolved much of the complexity and controversy in this area by confirming the classification proposed by Coleman, et al. Two issues that remained unresolved were (1) the inabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f417ba8e0b8e59d93c23a35925ce2868
https://pubmed.ncbi.nlm.nih.gov/8590276
https://pubmed.ncbi.nlm.nih.gov/8590276
Publikováno v:
Investigative ophthalmologyvisual science. 35(11)
The existence of integral membrane proteins that serve as selective water channels has been postulated to explain the movement of water across plasma membranes. Aquaporin CHIP (channel-forming integral membrane protein of 28 kd) is the first such cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b71a94d8bd6f8cf5f4e437cc4434de68
https://pubmed.ncbi.nlm.nih.gov/7523327
https://pubmed.ncbi.nlm.nih.gov/7523327