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pro vyhledávání: '"J W, Putney"'
Autor:
J. W. Putney
Publikováno v:
Cell Calcium. 42:103-110
Activation of phospholipase C by G-protein-coupled receptors results in release of intracellular Ca 2+ and activation of Ca 2+ channels in the plasma membrane. The intracellular release of Ca 2+ is signaled by the second messenger, inositol 1,4,5-tri
Autor:
J. W. Putney
Publikováno v:
Journal of Cell Science. 120:1959-1965
Capacitative Ca2+ entry links the emptying of intracellular Ca2+ stores to the activation of store-operated Ca2+ channels in the plasma membrane. In the twenty years since the inception of the concept of capacitative Ca2+ entry, a number of activatio
Autor:
J. W. Putney, C. M. Pedrosa Ribeiro
Publikováno v:
Cellular and Molecular Life Sciences. 57:1272-1286
This review discusses multiple ways in which the endoplasmic reticulum participates in and is influenced by signal transduction pathways. The endoplasmic reticulum provides a Ca2+ store that can be mobilized either by calcium-induced calcium release
Publikováno v:
Cell Calcium. 21:253-256
The role of cytoplasmic calcium as a regulator of phospholipase C in vasopressin-activated hepatocytes was examined. According to models in which calcium spiking arises because of a positive feedback by calcium on phospholipase C, Ca2+ is seen as a p
Publikováno v:
Journal of Biological Chemistry. 268:8425-8428
Stimulation of mouse lacrimal acinar cells with submaximal concentrations of the muscarinic agonist, methacholine, resulted in an increase in intracellular calcium ([Ca2+]i), which took the form of sinusoidal oscillations. These oscillations were rel
Publikováno v:
Journal of Biological Chemistry. 267:17722-17725
In saponin-permeabilized mouse lacrimal acinar cells, glycerophosphoryl-myo-inositol 4,5-bisphosphate (GPIP2) activated the release of sequestered Ca2+ to the same extent as inositol 1,4,5-trisphosphate ((1,4,5)IP3) but with a potency about 1/10 that
Publikováno v:
Handbook of experimental pharmacology. (179)
The canonical transient receptor potential (TRPC) cation channels are mammalian homologs of the photoreceptor channel TRP in Drosophila melanogaster. All seven TRPCs (TRPC1 through TRPC7) can be activated through Gq/11 receptors or receptor tyrosine
Autor:
J. W. Putney
Publikováno v:
Science's STKE. 2004
A major mechanism whereby calcium entry into cells is regulated is the store-operated or capacitative calcium entry pathway. In this article, two basic issues are discussed: (i) the methods investigators use to measure store-operated entry, and (ii)
Autor:
J W, Putney
Publikováno v:
Molecular interventions. 1(2)
The versatility of Ca(2+) as a messenger in multiple signaling events requires that the concentration of calcium ions within the cytoplasm be highly regulated. In particular, the release of calcium from intracellular stores must often be linked to ca
Autor:
J. W. Putney, Gary S. Bird
Publikováno v:
Journal of Biological Chemistry. 268:21486-21488
Injection of mouse lacrimal acinar cells with the non-hydrolyzable analogue of GTP, GTP gamma S (guanosine 5‘-3-O-(thio)triphosphate), caused a rapid release of intracellular calcium but failed to activate calcium entry. Injection of GTP gamma S to