Zobrazeno 1 - 10
of 44
pro vyhledávání: '"J W, Parce"'
Publikováno v:
Clinical Chemistry. 40:1800-1804
Over the past 5 years, microphysiometry has proved an effective means for detecting physiological changes in cultured cells, particularly as a functional assay for the activation of many cellular receptors. To demonstrate the clinical relevance of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af07c309ccba3a4915e5fc60cadf2f4f
https://doi.org/10.1093/clinchem/40.9.1800
https://doi.org/10.1093/clinchem/40.9.1800
Autor:
S Pitchford, Harden M. McConnell, J. W. Parce, D.L. Miller, John C. Owicki, G T Baxter, H G Wada
Publikováno v:
Science. 257:1906-1912
A silicon-based device, dubbed a microphysiometer, can be used to detect and monitor the response of cells to a variety of chemical substances, especially ligands for specific plasma membrane receptors. The microphysiometer measures the rate of proto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5787fe38a35b49e881df0865de298cbc
https://doi.org/10.1126/science.1329199
https://doi.org/10.1126/science.1329199
Antigen-specific stimulation of T cell extracellular acidification by MHC class II-peptide complexes
Publikováno v:
The Journal of Immunology. 148:2040-2044
A specific T cell response to a preformed complex of detergent-solubilized MHC class II molecule and cognate antigenic peptide was observed by monitoring the extracellular acidification. An increase in this rate was observed when the resting 4R3.9 T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c80a563b2d93d4c5c4714ba214f18053
https://doi.org/10.4049/jimmunol.148.7.2040
https://doi.org/10.4049/jimmunol.148.7.2040
Autor:
J. W. Parce, Anne R. Kopf-Sill, Theo T. Nikiforov, Luc J. Bousse, A Chow, C. Cohen, Robert S. Dubrow
Publikováno v:
Annual review of biophysics and biomolecular structure. 29
▪ Abstract Electrokinetic forces are emerging as a powerful means to drive microfluidic systems with flow channel cross-sectional dimensions in the tens of micrometers and flow rates in the nanoliter per second range. These systems provide many adv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed24783ad0200e5aa527d565b21e98a
https://pubmed.ncbi.nlm.nih.gov/10940246
https://pubmed.ncbi.nlm.nih.gov/10940246
Publikováno v:
SPIE Proceedings.
Many research groups around the world are working on integrated microfluidics. The goal of these projects is to automate and integrate the handling of liquid samples and reagents for measurement and assay procedures in chemistry and biology. Ultimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79d06094e32ffcfae78ef4ffc6eb2c11
https://doi.org/10.1117/12.307326
https://doi.org/10.1117/12.307326
Publikováno v:
SPIE Proceedings.
The use of microchips for performing biochemical processes has the potential to reduce reagent use and thus assay costs, increase throughput, and automate complex processes. We are building a multifunctional platform that provides sensing and actuati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b23f367a938802b6890c5f0505ca1814
https://doi.org/10.1117/12.269974
https://doi.org/10.1117/12.269974
Publikováno v:
Clinical chemistry. 40(9)
Over the past 5 years, microphysiometry has proved an effective means for detecting physiological changes in cultured cells, particularly as a functional assay for the activation of many cellular receptors. To demonstrate the clinical relevance of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c556a2bdb5e108715b93b4b755097e75
https://pubmed.ncbi.nlm.nih.gov/8070104
https://pubmed.ncbi.nlm.nih.gov/8070104
Publikováno v:
Annual review of biophysics and biomolecular structure. 23
PRINCIPLES OF THE LIGHT-ADDRESSABLE POTENTIOMETRIC SENSOR 88 Measurement of pH 89 The Photoeffect 90 Light Addressability 93 Measurement of Other Chemical Species 93 THE LAPS AS A SENSOR IN AN ANALYTICAL SYSTEM 94 Electrical Measurement of Phospholip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c623636ad7509c8f39ecca881053b42
https://pubmed.ncbi.nlm.nih.gov/7919801
https://pubmed.ncbi.nlm.nih.gov/7919801
Antigen-specific stimulation of T cell extracellular acidification by MHC class II-peptide complexes
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 148(7)
A specific T cell response to a preformed complex of detergent-solubilized MHC class II molecule and cognate antigenic peptide was observed by monitoring the extracellular acidification. An increase in this rate was observed when the resting 4R3.9 T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0422896c25fa3269458c71cf903f47a7
https://pubmed.ncbi.nlm.nih.gov/1372021
https://pubmed.ncbi.nlm.nih.gov/1372021
Autor:
John C. Owicki, J. W. Parce
Publikováno v:
Biosensorsbioelectronics. 7(4)
The silicon microphysiometer is a biosensor-based instrument that detects changes in the physiological state of cultured living cells by monitoring the rate at which the cells excrete acidic products of metabolism. This paper discusses the chemical a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ec97f1c5379def381ce8ce168fb44e
https://pubmed.ncbi.nlm.nih.gov/1622600
https://pubmed.ncbi.nlm.nih.gov/1622600