Zobrazeno 1 - 10
of 32
pro vyhledávání: '"J W, MacCluer"'
Autor:
V. P. Diego, L. Almasy, D. L. Rainwater, M. C. Mahaney, A. G. Comuzzie, S. A. Cole, R. P. Tracy, M. P. Stern, J. W. MacCluer, J. Blangero
Publikováno v:
International Journal of Vascular Medicine, Vol 2010 (2010)
Background. D-dimer is associated with increasing severity of atherosclerosis and with increased risk of a cardiovascular disease (CVD). Methods and Results. To better understand this risk factor, we performed a genome scan on 803 (301 males and 502
Externí odkaz:
https://doaj.org/article/94e690e510c8400a869e310a4e4e5a1f
Publikováno v:
Diabetes. 43:942-946
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7d84cdcfcf3f17099c7abbe102fc415
https://doi.org/10.2337/diabetes.43.7.942
https://doi.org/10.2337/diabetes.43.7.942
Publikováno v:
Human biology. 72(3)
The fertility of a large sample of American Indian women participating in the Strong Heart Study was examined to determine which factors are associated with variation in completed fertility among women in this population. The Strong Heart Study (SHS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5bf66e158275b9344701e4fe69e651a0
https://pubmed.ncbi.nlm.nih.gov/10885187
https://pubmed.ncbi.nlm.nih.gov/10885187
Autor:
B D, Mitchell, S A, Cole, R L, Bauer, S J, Iturria, E A, Rodriguez, J, Blangero, J W, MacCluer, J E, Hixson
Publikováno v:
The Journal of clinical endocrinology and metabolism. 85(4)
Osteocalcin (OC) is an important constituent of bone that is synthesized by osteoblasts. Serum levels of OC have been used as a biochemical marker of bone turnover. To identify the genes influencing variation in serum OC levels, we conducted a genome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67dcd99c92c7c6de38b5622d1a7666ed
https://pubmed.ncbi.nlm.nih.gov/10770166
https://pubmed.ncbi.nlm.nih.gov/10770166
Autor:
J, Benhorin, M, Goldmit, J W, MacCluer, J, Blangero, R, Goffen, A, Leibovitch, A, Rahat, Q, Wang, A, Medina, J, Towbin, B, Kerem
Publikováno v:
Human mutation. 12(1)
The long QT syndrome (LQT) is an inherited cardiac disorder that can cause sudden cardiac death among apparently healthy young individuals due to malignant ventricular arrhythmias. LQT was found to be caused by mutations in four genes LTQ1, LQT2, LQT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2975e50e8734c4d6dacf02d4648b96df
https://pubmed.ncbi.nlm.nih.gov/10627139
https://pubmed.ncbi.nlm.nih.gov/10627139
Autor:
J E, Hixson, L, Almasy, S, Cole, S, Birnbaum, B D, Mitchell, M C, Mahaney, M P, Stern, J W, MacCluer, J, Blangero, A G, Comuzzie
Publikováno v:
The Journal of clinical endocrinology and metabolism. 84(9)
We previously reported that our genome-scanning initiative had detected a highly significant linkage (log odds ratio = 4.95; P = 9 x 10(-7)) between a quantitative trait locus (QTL) on chromosome 2 and leptin levels in Mexican American families. We n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::761e17288b24f9292467970c094ad119
https://pubmed.ncbi.nlm.nih.gov/10487685
https://pubmed.ncbi.nlm.nih.gov/10487685
Publikováno v:
Genetic epidemiology. 14(6)
GAW10 Problem 2 involves a simulated common disease defined by imposing a threshold, T, on a quantitative trait, Q1. Every individual with a value of Q1or = T (where T = 40) is defined as affected. Also thought to be associated with the disease as in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21171195bb6a4bd4cc8a6f42e2ed1f22
https://pubmed.ncbi.nlm.nih.gov/9433570
https://pubmed.ncbi.nlm.nih.gov/9433570
Autor:
A G, Comuzzie, J, Blangero, M C, Mahaney, B D, Mitchell, J E, Hixson, P B, Samollow, M P, Stern, J W, MacCluer
Publikováno v:
Genetic epidemiology. 12(5)
Increased adiposity has repeatedly been identified as a major risk factor for a variety of chronic diseases. However, the question still remains whether the amount of adipose tissue itself is genetically mediated. To address this question, a segregat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::421b7f0d5e6e7bc887824b06c5fad370
https://pubmed.ncbi.nlm.nih.gov/8557180
https://pubmed.ncbi.nlm.nih.gov/8557180
Publikováno v:
Genetic epidemiology. 12(6)
For Problem 2, simulated family data were provided for a common oligogenic disease that was defined by imposing a threshold, T, on a quantitative trait, Q1. Every individual with a value of Q1T (where T = 87.5) was defined as affected. Participants w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d04e1a3880e7f4d9b96455a0ceeab6a
https://pubmed.ncbi.nlm.nih.gov/8787996
https://pubmed.ncbi.nlm.nih.gov/8787996
Autor:
L R, Weitkamp, A J, Moss, R A, Lewis, W J, Hall, J W, MacCluer, P J, Schwartz, E H, Locati, D, Tzivoni, G M, Vincent, J L, Robinson
Publikováno v:
American journal of human genetics. 55(6)
The long-QT (LQT) syndrome is a genetically complex disorder that is characterized by syncope and fatal ventricular arrhythmias. LQT syndrome, as defined by a prolonged electrocardiographic QT interval, has a higher incidence in females than in males
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb63a7bb8bec6c65daa9e234600de759
https://pubmed.ncbi.nlm.nih.gov/7977384
https://pubmed.ncbi.nlm.nih.gov/7977384