Zobrazeno 1 - 10
of 215
pro vyhledávání: '"J W, Huggins"'
Autor:
J. R. Swearengen, N. K. Jaax, Peter B. Jahrling, J. B. Geisbert, Thomas W. Geisbert, Clarence J. Peters, M. Bray, J. W. Huggins, James W. LeDuc
Publikováno v:
The Journal of Infectious Diseases. 179:S224-S234
A passive immunization strategy for treating Ebola virus infections was evaluated using BALB/ c mice, strain 13 guinea pigs, and cynomolgus monkeys. Guinea pigs were completely protected by injection of hyperimmune equine IgG when treatment was initi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e8795b16c1a69b867a29f8fc1f25e6
https://doi.org/10.1086/514310
https://doi.org/10.1086/514310
Publikováno v:
Archives of pathologylaboratory medicine. 124(3)
To determine the morphologic changes and disease progression of aerosolized cowpox virus infection in BALB/c mice and to ascertain the suitability of cowpox virus-infected BALB/c mice as a model of aerosol-transmitted, orthopoxviral respiratory disea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2da6e34efead0bfa98512c48572894d
https://pubmed.ncbi.nlm.nih.gov/10705388
https://pubmed.ncbi.nlm.nih.gov/10705388
Autor:
K J, Davis, A O, Anderson, T W, Geisbert, K E, Steele, J B, Geisbert, P, Vogel, B M, Connolly, J W, Huggins, P B, Jahrling, N K, Jaax
Publikováno v:
Archives of pathologylaboratory medicine. 121(8)
Ebola virus has been responsible for explosive lethal outbreaks of hemorrhagic fever in both humans and nonhuman primates. Previous studies showed a predilection of Ebola virus for cells of the mononuclear phagocyte system and endothelial cells.To ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::12f3c4219cb0b8e3abddaa0ca1a84674
https://pubmed.ncbi.nlm.nih.gov/9278608
https://pubmed.ncbi.nlm.nih.gov/9278608
Autor:
P B, Jahrling, J, Geisbert, J R, Swearengen, G P, Jaax, T, Lewis, J W, Huggins, J J, Schmidt, J W, LeDuc, C J, Peters
Publikováno v:
Archives of virology. Supplementum. 11
A commercially available immunoglobulin G (IgG) from horses, hyperimmunized to Ebola virus, was evaluated for its ability to protect cynomolgus monkeys against disease following i.m. inoculation with 1 000 PFU Ebola virus (Zaire '95 strain). Six monk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10280f0f22d38d021c83744700329c5a
https://pubmed.ncbi.nlm.nih.gov/8800795
https://pubmed.ncbi.nlm.nih.gov/8800795
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 20(3)
The pharmacokinetics of 3-deazaneplanocin A (c3Nep), a competitive inhibitor of S-adenosyl-L-homocysteine (AdoHcy) hydrolase and novel antiviral agent, was investigated in female BALB/c mice. Animals were given a single intravenous dose of [3H]-c3Nep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3aa67bb2c03f975ac8b4b801ec9530e
https://pubmed.ncbi.nlm.nih.gov/8751041
https://pubmed.ncbi.nlm.nih.gov/8751041
Autor:
T M, Zhang, Z Q, Yang, M Y, Zhang, Z J, Hu, J M, Xiang, J W, Huggins, T M, Cosgriff, J I, Smith
Publikováno v:
Chinese medical journal. 106(8)
We analysed the early viremia and clinical tests in 82 patients with epidemic hemorrhagic fever (EHF). The results showed that the changes in viremia and clinical tests are related to the severity of the disease and prognosis. Higher concentrations o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::133e0692424714b443094cef6c2a01c0
https://pubmed.ncbi.nlm.nih.gov/7900974
https://pubmed.ncbi.nlm.nih.gov/7900974
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 21(4)
The pharmacokinetics of carbocyclic 3-deazaadenosine (Cc3Ado), a competitive inhibitor of S-adenosyl-L-homocysteine hydrolase and novel antiviral agent, was investigated in female BALB/c mice. Mice were dosed either orally or intravenously with a sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49cda7ccd385d7956ce425ea9e2bf8df
https://pubmed.ncbi.nlm.nih.gov/8104112
https://pubmed.ncbi.nlm.nih.gov/8104112
Autor:
Z Q, Yang, T M, Zhang, M V, Zhang, Z M, Zheng, Z J, Hu, C F, Qu, J M, Xiang, J W, Huggins, T M, Cosgriff, J I, Smith
Publikováno v:
Chinese medical journal. 104(2)
Kinetic changes of viremia were observed in 287 cases of hemorrhagic fever with renal syndrome (HFRS) in whom ribavirin was administered with double blind random control studied by means of virus isolation, indirect immunofluorescence assay and enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bad66b17ca6a34d265e0583601436ec
https://pubmed.ncbi.nlm.nih.gov/1678691
https://pubmed.ncbi.nlm.nih.gov/1678691
Autor:
Denis, Maxime1 (AUTHOR), Blais, Samuel1 (AUTHOR), Canesi, Sylvain1 (AUTHOR) canesi.sylvain@uqam.ca
Publikováno v:
Advanced Synthesis & Catalysis. 10/24/2023, Vol. 365 Issue 20, p3521-3526. 6p.
Autor:
Sun, Chunzhao, Inokuma, Tsubasa, Tsuji, Daisuke, Yamaoka, Yousuke, Akagi, Reiko, Yamada, Ken-ichi
Publikováno v:
Chemical Communications; 7/7/2024, Vol. 60 Issue 53, p6757-6760, 4p