Zobrazeno 1 - 10
of 19
pro vyhledávání: '"J W, Heinecke"'
Autor:
Xue-Qiao Zhao, Daniel S. Hippe, J W Heinecke, Tomas Vaisar, Patrick M. Moriarty, J Dutton, L K Denney
Publikováno v:
European Heart Journal. 39
Publikováno v:
Current Medicinal Chemistry. 8:829-838
Increased aerobic metabolism during exercise is a potential source of oxidative stress. In muscle, mitochondria are one important source of reactive intermediates that include superoxide (O2*-), hydrogen peroxide (H2O2), and possibly hydroxyl radical
Autor:
C. F. Semenkovich, J. W. Heinecke
Publikováno v:
Diabetes. 46:327-334
Publikováno v:
Pneumologie. 59
Publikováno v:
European journal of biochemistry. 268(12)
The structural integrity of apolipoprotein A-I (apo A-I) is critical to the physiological function of high-density lipoprotein (HDL). Oxidized lipoproteins are thought to be of central importance in atherogenesis, and oxidation products characteristi
Publikováno v:
The Journal of biological chemistry. 276(11)
The existence of interhalogen compounds was proposed more than a century ago, but no biological roles have been attributed to these highly oxidizing intermediates. In this study, we determined whether the peroxidases of white blood cells can generate
Publikováno v:
Journal of lipid research. 41(7)
Reactive aldehydes can be formed during the oxidation of lipids, glucose, and amino acids and during the nonenzymatic glycation of proteins. Low density lipoprotein (LDL) modified with malondialdehyde are taken up by scavenger receptors on macrophage
Autor:
J W, Heinecke, F F, Hsu, J R, Crowley, S L, Hazen, C, Leeuwenburgh, D M, Mueller, J E, Rasmussen, J, Turk
Publikováno v:
Methods in enzymology. 300
Publikováno v:
Methods in enzymology. 300
Publikováno v:
The Journal of biological chemistry. 273(9)
We have recently demonstrated that neutrophils oxidize nearly all of the amino acids commonly found in plasma to a corresponding family of aldehydes in high yield. The reaction is mediated by hypochlorous acid (HOCl), the major oxidant generated by t