Zobrazeno 1 - 10
of 10
pro vyhledávání: '"J W, Höppener"'
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 144(42)
Type 2 diabetes mellitus is a heterogeneous and multifactorial disorder accompanied by severe complications and a reduced life expectancy. Histopathologically, it is characterized by deposition of protein in the islets of Langerhans in the pancreas (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59ecfd013e7f331f2037ba9928236618
https://pubmed.ncbi.nlm.nih.gov/11072517
https://pubmed.ncbi.nlm.nih.gov/11072517
Autor:
J F, Roijers, M J, de Wit, R B, van der Luijt, H K, Ploos van Amstel, J W, Höppener, C J, Lips
Publikováno v:
European journal of clinical investigation. 30(6)
Multiple endocrine neoplasia type 1 (MEN 1) is an autosomal, dominantly inherited cancer syndrome, with tumours in various endocrine glands. In 1997 the responsible tumour suppressor gene was identified. MEN1 gene germ-line mutations are detected in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0eee29c64ab53626fd6667bac90c200f
https://pubmed.ncbi.nlm.nih.gov/10849016
https://pubmed.ncbi.nlm.nih.gov/10849016
Autor:
F J, Hes, P J, Slootweg, T J, van Vroonhoven, R J, Hené, M A, Feldberg, R A, Zewald, J K, Ploos van Amstel, J W, Höppener, P L, Pearson, C J, Lips
Publikováno v:
European journal of clinical investigation. 29(1)
An evaluation of nephron-sparing surgery (NSS) or radical nephrectomy (RN) for treating renal cell carcinoma (RCC) in patients with von Hippel-Lindau disease (VHL) was carried out.Between 1976 and 1997, 10 patients with RCC from four VHL families, of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::392c0651dccab8fe72fe8acb83e2b542
https://pubmed.ncbi.nlm.nih.gov/10092992
https://pubmed.ncbi.nlm.nih.gov/10092992
Autor:
J W, Höppener, M J, De Wit, A Y, Simarro-Doorten, J F, Roijers, H M, van Herrewaarden, C J, Lips, F, Parente, D, Quincey, P, Gaudray, S, Khodaei, G, Weber, B, Teh, F, Farnebo, C, Larsson, C X, Zhang, A, Calender, A A, Pannett, S A, Forbes, J H, Bassett, R V, Thakker, I, Lemmens, W J, Van de Ven, K, Kas
Publikováno v:
Genomics. 50(2)
In the process of identification of the multiple endocrine neoplasia type 1 gene, which was recently published, we isolated a novel gene in the 11q13 region. This gene (named ZFPL1, for zinc-finger protein-like 1) is expressed strongly in the exocrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8fe377eb7b73278b3d65bac69e549166
http://ora.ox.ac.uk/objects/uuid:570ef722-ae93-4bd5-93ed-3471f1175715
http://ora.ox.ac.uk/objects/uuid:570ef722-ae93-4bd5-93ed-3471f1175715
Autor:
C, Oosterwijk, K L, van Hulst, C J, Visser, R A, Woutersen, C J, Lips, J G, van den Tweel, J W, Höppener
Publikováno v:
International journal of cancer. 72(4)
Many patients with exocrine pancreatic cancer develop diabetes mellitus due to insulin resistance. This may relate to concurrent over-production of islet amyloid polypeptide (IAPP) by the pancreatic beta cells. We investigated the effects of pancreat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d114bd75e22df7c776d620f1e2843d6f
https://pubmed.ncbi.nlm.nih.gov/9259404
https://pubmed.ncbi.nlm.nih.gov/9259404
Autor:
R M, Landsvater, M J, de Wit, R A, Zewald, R M, Hofstra, C H, Buys, H K, Ploos van Amstel, J W, Höppener, C J, Lips
Publikováno v:
Cancer research. 56(21)
Germ line mutations in one allele of the RET proto-oncogene predispose to the multiple endocrine neoplasia type 2 (MEN 2) syndromes. To investigate whether these inherited mutations alone can cause the development of tumors in vivo (oncogene model) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ad72e0997a077920b470937e6019475
https://pubmed.ncbi.nlm.nih.gov/8895732
https://pubmed.ncbi.nlm.nih.gov/8895732
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 138(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e434cf8e95d5335983029aa12077965
https://pubmed.ncbi.nlm.nih.gov/7906400
https://pubmed.ncbi.nlm.nih.gov/7906400
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 137(15)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e2f4e76e24b32528911f4a4360542d7
https://pubmed.ncbi.nlm.nih.gov/8479567
https://pubmed.ncbi.nlm.nih.gov/8479567
Publikováno v:
Cancer research. 46(6)
Generalized hypomethylation of the genome and of specific genes has been described in human tumors. We now report that in human lung cancers, especially in the most aggressive form, small cell lung carcinoma, and in lymphomas, the 5'-region of the ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75110cf88b0ae1d642e3af732c6fe5a7
https://pubmed.ncbi.nlm.nih.gov/3009002
https://pubmed.ncbi.nlm.nih.gov/3009002
Publikováno v:
Henry Ford Hospital medical journal. 32(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cdaa4a15c11a4a387da60fa25f963388
https://pubmed.ncbi.nlm.nih.gov/6152465
https://pubmed.ncbi.nlm.nih.gov/6152465