Výsledky vyhledávání

GSK1562590, a slowly dissociating urotensin-II receptor antagonist, exhibits prolonged pharmacodynamic activity ex vivo

Autor: D J, Behm, N V, Aiyar, A R, Olzinski, J J, McAtee, M A, Hilfiker, J W, Dodson, S E, Dowdell, G Z, Wang, K B, Goodman, C A, Sehon, M R, Harpel, R N, Willette, M J, Neeb, C A, Leach, S A, Douglas

Publikováno v: British journal of pharmacology. 161(1)

Recently identified antagonists of the urotensin-II (U-II) receptor (UT) are of limited utility for investigating the (patho)physiological role of U-II due to poor potency and limited selectivity and/or intrinsic activity.The pharmacological properti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b2b838c556c480e5389b862896a4f70e
https://pubmed.ncbi.nlm.nih.gov/20718751

Zobrazit plný text záznamu

Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues

Autor: D J, Behm, J J, McAtee, J W, Dodson, M J, Neeb, H E, Fries, C A, Evans, R R, Hernandez, K D, Hoffman, S M, Harrison, J M, Lai, C, Wu, N V, Aiyar, E H, Ohlstein, S A, Douglas

Publikováno v: British journal of pharmacology. 155(3)

The recent development of the UT ligand palosuran (1-[2-(4-benzyl-4-hydroxy-piperidin-1-yl)-ethyl]-3-(2-methyl-quinolin-4-yl)-urea sulphate salt) has led to the proposition that urotensin-II (U-II) plays a significant pathological role in acute and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9940b321f206152091724b5bba433860
https://pubmed.ncbi.nlm.nih.gov/18587423

Zobrazit plný text záznamu

The differentiation of epidermis II. Alternative pathways of differentiation of embryonic chicken epidermis in organ culture

Autor: J. W. Dodson

Publikováno v: Development. 17:107-117

Two series of experiments were made to determine the possible alteration of paths of differentiation of the epidermis from the metatarsal region of 12-day chicken embryos. The epidermis, separated from dermis after Versene treatment of the skin, eith

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::393ded7c1c12d515390ffcd29f80b31c
https://doi.org/10.1242/dev.17.1.107

Zobrazit plný text záznamu

Ophthalmology for the family doctor

Autor: J W, DODSON

Publikováno v: The Journal of the Arkansas Medical Society. 48(12)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::461b989dd00928761563a403b0cb44d1
https://pubmed.ncbi.nlm.nih.gov/14938277

Zobrazit plný text záznamu

The differentiation of epidermis. II. Alternative pathways of differentiation of embryonic chicken epidermis in organ culture

Autor: J W, Dodson

Publikováno v: Journal of embryology and experimental morphology. 17(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d36b5c004869fd1e2ff18f032543d04f
https://pubmed.ncbi.nlm.nih.gov/6040542

Zobrazit plný text záznamu

Secretion of collagen by corneal epithelium. I. Morphology of the collagenous products produced by isolated epithelia grown on frozen-killed lens

Autor: E D, Hay, J W, Dodson

Publikováno v: The Journal of Cell Biology

Corneal epithelium from 5-7-day old chick embryos was isolated with EDTA and grown in culture on frozen-killed lens as a substratum. Autoradiographs showed that in the presence of [(3)H]proline, the corneal epithelium synthesized and secreted onto th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b7f6d894d1814d7f309432478982d86f
https://pubmed.ncbi.nlm.nih.gov/4347977

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání