Zobrazeno 1 - 10
of 36
pro vyhledávání: '"J W, Boellaard"'
Publikováno v:
Ultrastructural Pathology. 30:387-391
The ultrastructure of lipofuscin (Lf) was studied in hippocampal and neocortical neurons of children and youngsters between 3 months and 24 years of age. As a standard, regions CA1 and CA4 of Ammon's horn and the gyrus centralis anterior of the left
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536dced823f0e54aa6dec4286c1c57f4
https://doi.org/10.1080/01913120600854137
https://doi.org/10.1080/01913120600854137
Publikováno v:
Ultrastructural Pathology. 28:341-351
Lipofuscin represents an integral part of neurons and glial cells in mammals and in submammalian species. It is a special lysosomal organelle, takes part of cellular metabolism, and is a structural expression of catabolic pathways. Species-specific d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6162c2afa1b4035494506e40a430c040
https://doi.org/10.1080/019131290882330
https://doi.org/10.1080/019131290882330
Autor:
Nicolas Kopp, Paul Brown, Nathalie Streichenberger, Jean-Jacques Hauw, Pierric Giraud, J. W. Boellaard, Beata Sikorska, Pawel P. Liberski, Herbert Budka
Publikováno v:
Virus Research. 132:226-228
Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler-Scheinker disease (GSS) and Fatal Familial Insomnia (FFI) are slow neurodegenerative disorders classified as transmissible spongiform encephalopathies (TSEs) or prion diseases, which appear in spo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5cd6fb2ff919f12f6ce23f3e818c23
https://doi.org/10.1016/j.virusres.2007.11.008
https://doi.org/10.1016/j.virusres.2007.11.008
Publikováno v:
Acta Neuropathologica. 83:559-563
It was difficult to make a definite pathological diagnosis in a 73-year-old man with Creutzfeldt-Jakob disease (CJD) due to extensive amyloid angiopathy which lacked any severe spongiform changes. Immunostaining using anti-prion protein (PrP) antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d92e0c5a255b2588cad7d942f1633fb
https://doi.org/10.1007/bf00310037
https://doi.org/10.1007/bf00310037
Publikováno v:
Acta Neuropathologica. 82:225-228
In this study we report the formation of giant autophagic vacuoles (AV) in neurons in experimental scrapie in hamsters. Autophagy is an important step in the cellular turnover of proteins and organelles. It is known to occur in neurons under physiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16684e509047fb736aab1af1e7e2c492
https://doi.org/10.1007/bf00294449
https://doi.org/10.1007/bf00294449
Autor:
David M. Asher, J. W. Boellaard, Paul Brown, D. Carleton Gajdusek, Pedro Piccardo, W. Ted Brown, Lev G. Goldfarb, Dmitry Goldgaber, Richard J. Kascsak, Richard Rubenstein
Publikováno v:
Experimental Neurology. 108:247-250
We and others have recently reported that patients with the Gerstmann-Sträussler-Scheinker syndrome have a mutation at codon 102 of the gene coding for amyloid protein that accumulates in this disease. We report here that this mutation was not found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5801d55a6516166ba78f095e30d0b4fd
https://doi.org/10.1016/0014-4886(90)90130-k
https://doi.org/10.1016/0014-4886(90)90130-k
Publikováno v:
Neuropathology and Applied Neurobiology. 16:85-89
The antigenicity of the 'prion' protein amyloid fibrils was shown to be preserved after glutaraldehyde/OsO4 fixation in uranyl acetate-stained brain tissue blocks from patients with Gerstmann-Straussler syndrome (GSS) and from mice infected with Creu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb720ef9ecb2a5dc3d26554d8144848a
https://doi.org/10.1111/j.1365-2990.1990.tb00934.x
https://doi.org/10.1111/j.1365-2990.1990.tb00934.x
Publikováno v:
Clinical neuropathology. 18(6)
Gerstmann-Sträussler-Scheinker disease (GSSD) is a hereditary as well as transmissible human prion disease, restricted to families carrying point mutations of the PRPN gene on chromosome 20. To date 7 different causative mutations have been found. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf50ad11086a04fcdc8c13adef4ed896
https://pubmed.ncbi.nlm.nih.gov/10580553
https://pubmed.ncbi.nlm.nih.gov/10580553
Autor:
N, Heldt, J W, Boellaard, P, Brown, L, Cervenákova, J, Doerr-Schott, C, Thomas, C, Scherer, F, Rohmer
Publikováno v:
Clinical neuropathology. 17(4)
We report a kindred of French/Alsatian origin with symptoms of Gerstmann-Sträussler-Scheinker disease over 3 generations. In the propositus, cerebellar signs and memory disturbance were the presenting features, followed by other neurological manifes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::606aceae55da84ee7affda6cafbe3bec
https://pubmed.ncbi.nlm.nih.gov/9707339
https://pubmed.ncbi.nlm.nih.gov/9707339
Autor:
J. W. Boellaard
Publikováno v:
Pathologie ISBN: 9783642851803
Dieser Gruppe von Erkrankungen des ZNS, die bei Menschen und Haustieren vorkommen, ist eine ungewohnlich lange Inkubationszeit und dann ein meist rascher todlicher Verlauf gemeinsam. Die bekanntesten hierzu gehorigen Krankheiten, die im folgenden bes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f3b77a6a0f66e40aecc9a1f7cbae056
https://doi.org/10.1007/978-3-642-85179-7_11
https://doi.org/10.1007/978-3-642-85179-7_11
