Výsledky vyhledávání - "J W, Apriletti"

Roles of 3,5,3'-triiodothyronine and deoxyribonucleic acid binding on thyroid hormone receptor complex formation

Autor: J H Brubaker, William W. Chin, J. D. Baxter, J. W. Apriletti, Paul M. Yen

Publikováno v: Endocrinology. 134:1075-1081

Thyroid hormone receptors (TRs) bind to thyroid hormone response elements (TREs) in the promoter region of target genes as monomers, homodimers, and heterodimers with nuclear proteins such as retinoid-X receptors (RXRs). Recently, we observed that T3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7dfc0601cf58f59cf82a3422365b2f
https://doi.org/10.1210/endo.134.3.8119145

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Phosphorylation selectively increases triiodothyronine receptor homodimer binding to DNA

Autor: David B. Sacks, William W. Chin, Akira Sugawara, J. W. Apriletti, Paul M. Yen, R. C. J. Ribeiro, J. D. Baxter

Publikováno v: Journal of Biological Chemistry. 269:433-437

Thyroid hormone receptors (TRs) are ligand-regulated transcription factors that bind to thyroid hormone response elements (TREs) as monomers and homodimers, and as heterodimers with nuclear proteins such as TR auxiliary proteins and retinoid X recept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc16d4c9d3f237a3c68b46cb9d8aa0d9
https://doi.org/10.1016/s0021-9258(17)42369-6

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Mechanisms of thyroid hormone action: insights from X-ray crystallographic and functional studies

Autor: R C, Ribeiro, J W, Apriletti, R L, Wagner, B L, West, W, Feng, R, Huber, P J, Kushner, S, Nilsson, T, Scanlan, R J, Fletterick, F, Schaufele, J D, Baxter

Publikováno v: Recent progress in hormone research. 53

This review summarizes the studies conducted in our laboratory on the mechanisms of thyroid hormone action over the past two decades. We have attempted to place our studies on thyroid hormone receptors (TRs) in perspective with the work conducted by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d7bb21e77ab1f168dacb62c6ba083cfa
https://pubmed.ncbi.nlm.nih.gov/9769715

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Delineation of three different thyroid hormone-response elements in promoter of rat sarcoplasmic reticulum Ca2+ATPase gene. Demonstration that retinoid X receptor binds 5' to thyroid hormone receptor in response element 1

Autor: R, Hartong, N, Wang, R, Kurokawa, M A, Lazar, C K, Glass, J W, Apriletti, W H, Dillmann

Publikováno v: The Journal of biological chemistry. 269(17)

Thyroid hormone (3,5,3'-triiodothyronine) positively regulates transcription of the sarcoplasmic reticulum Ca2+ATPase gene in rat heart, and sequences within 559 nucleotides upstream from the transcription start site confer thyroid hormone responsive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::49e9eb3ec7cd28ebb8f325960c655fe6
https://pubmed.ncbi.nlm.nih.gov/8175722

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Affinity chromatography of thyroid hormone receptors. Biospecific elution from support matrices, characterization of the partially purified receptor

Autor: J D Baxter, Norman L. Eberhardt, K R Latham, J W Apriletti

Publikováno v: Journal of Biological Chemistry. 256:12094-12101

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abb3686a4cd7c45568ec42e89336ed65
https://doi.org/10.1016/s0021-9258(18)43238-3

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Development of support matrices for affinity chromatography of thyroid hormone receptors

Autor: J W Apriletti, K R Latham, Norman L. Eberhardt, J D Baxter

Publikováno v: Journal of Biological Chemistry. 256:12088-12093

Certain cellular responses to thyroid hormones appear to be mediated by non-histone chromatin protein receptors. Purification of these proteins is important for an investigation of the detailed mechanisms of their regulatory role. In the present stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b08b674b17a634c66f5063929251a1f5
https://doi.org/10.1016/s0021-9258(18)43237-1

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Cellular RNA synthesis in normal and mengovirus-infected L-929 cells

Autor: E E Penhoet, J W Apriletti

Publikováno v: Journal of Biological Chemistry. 253:603-611

Cellular RNA synthesis was studied in mouse L-929 cells and in these cells infected with mengovirus. RNA polymerases I, II, and III were partially purified and their chromatographic properties were analyzed by DEAE-Sephadex A-25 chromatography. RNA p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2007f9fe4b8a0f0fc95830e6c5df389f
https://doi.org/10.1016/s0021-9258(17)38251-0

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Interactions of the nuclear thyroid hormone receptor with core histones

Autor: J W, Apriletti, Y, David-Inouye, N L, Eberhardt, J D, Baxter

Publikováno v: The Journal of biological chemistry. 259(17)

These studies concern the interactions of the rat liver thyroid hormone nuclear receptor with histones and factors influencing the receptor's assay and stability. Heating certain crude receptor preparations at 50 degrees C produces a selective loss o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1b5e68883e3080e4403b2b7b83653855
https://pubmed.ncbi.nlm.nih.gov/6088522

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