Zobrazeno 1 - 10
of 164
pro vyhledávání: '"J Vilpo"'
Publikováno v:
Cytogenetic and Genome Research. 118:8-12
Although recurrent chromosomal alterations occur in chronic lymphocytic leukemia (CLL), relatively few affected tumor suppressors and oncogenes have been implicated. To improve genetic characterization of CLL, we performed high-resolution gene copy n
Autor:
J Vilpo, Terho Lehtimäki, Irina Elovaara, S Särkijärvi, H. Kuusisto, Heini Huhtala, Raija Paalavuo
Publikováno v:
Acta Neurologica Scandinavica. 113:163-166
Objectives – Therapy of acute exacerbations of multiple sclerosis (MS) with high-dose intravenous methylprednisolone (IVMP) has shortened the recovery period after relapses, but the mechanisms responsible for the beneficial effects of IVMP in attac
Publikováno v:
Die Pharmazie. 58(3)
A series of novel 5'-phthaloylnucleosides were synthesized via Mitsunobu reaction starting from AZT or 2'-deoxyadenosine and numerous phthalimides and their sulphur analogues-thioimides. Some of them showed significant anticancer activity.
Publikováno v:
British journal of haematology. 114(1)
We investigated responses to vaccination against pneumococcal polysaccharide, Haemophilus influenzae b (Hib) conjugate and tetanus toxoid antigens in 31 patients with chronic lymphocytic leukaemia (CLL) and 25 controls. While in the control group all
Publikováno v:
Haematologica. 85(9)
Chromosome band 11q23 is frequently deleted in various types of neoplasm. The region represented by yeast artificial chromosome (YAC) clone 755b11 at 11q23 has been shown to be the minimal common region of deletion in mantle cell lymphoma (MCL) and B
Publikováno v:
Haematologica. 85(8)
A major obstacle to the successful use of chemotherapy in the treatment of leukemia and other cancers is the emergence of drug resistance. One of the most studied resistance mechanisms is mediated by P-glycoprotein, which can be modulated by calcium
Publikováno v:
European journal of haematology. 65(1)
Drug resistance is a major problem in chemotherapy of chronic lymphocytic leukemia (CLL). The genetic basis and molecular pathogenesis of drug resistance in CLL remain poorly understood. Here, we have investigated the association between chromosomal
Publikováno v:
British journal of haematology. 100(3)
The production of the cytokines interleukin-6 (IL-6) and tumour necrosis factor-alpha (TNF-alpha) in B-CLL cells from 24 patients at different stages of chronic lymphocytic B-cell leukaemia (B-CLL) was investigated in vitro. In the majority of these
Publikováno v:
Genes, chromosomescancer. 19(4)
The genetic basis and molecular pathogenesis of chronic lymphocytic leukemia (CLL) and the molecular mechanisms responsible for its progression remain poorly understood. Here, karyotyping techniques specifically optimized for CLL, comparative genomic
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 40:311-318
Human monocytes and ascites macrophages from cirrhotic patients were isolated in Percoll-gradient and cultured with and without silica. Similar experiments were carried out also with cultured malignant human histiocytes and transformed mouse macropha