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Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group

Autor: Benjamin Lacas, Alexandra Carmel, Cécile Landais, Stuart J. Wong, Lisa Licitra, Jeffrey S. Tobias, Barbara Burtness, Maria Grazia Ghi, Ezra E.W. Cohen, Cai Grau, Gregory Wolf, Ricardo Hitt, Renzo Corvò, Volker Budach, Shaleen Kumar, Sarbani Ghosh Laskar, Jean-Jacques Mazeron, Lai-Ping Zhong, Werner Dobrowsky, Pirus Ghadjar, Carlo Fallai, Branko Zakotnik, Atul Sharma, René-Jean Bensadoun, Maria Grazia Ruo Redda, Séverine Racadot, George Fountzilas, David Brizel, Paolo Rovea, Athanassios Argiris, Zoltán Takácsi Nagy, Ju-Whei Lee, Catherine Fortpied, Jonathan Harris, Jean Bourhis, Anne Aupérin, Pierre Blanchard, Jean-Pierre Pignon, D.J. Adelstein, M. Alfonsi, Y. Belkacemi, V. Bar-Ad, J. Bernier, Å. Bratland, G. Calais, B. Campbell, J. Caudell, S. Chabaud, E. Chamorey, D. Chaukar, K.N. Choi, O. Choussy, L. Collette, J.J. Cruz, C. Dani, E. Dauzier, A.A. Forastiere, P. Garaud, V. Gregoire, A. Hackshaw, E. Haddad, B.G. Haffty, A. Hansen, S. Hayoz, J.C. Horiot, B. Jeremic, T.G. Karrison, J.A. Langendijk, M. Lapeyre, E. Lartigau, T. Leong, Q.T. Le, P.P.Y. Lee, F. Lewin, A. Lin, A. Lopes, S. Mehta, J. Moon, E. Moyal, B.V. Occéan, P. Olmi, R. Orecchia, B. O'Sullivan, J. Overgaard, C. Petit, H. Quon, G. Sanguineti, T. Satar, J. Simes, C. Simon, C. Sire, S. Staar, C. Stromberger, P. Strojan, S. Temam, D. Thomson, A. Timochenko, V. Torri, V. Tseroni, J. Vermorken, E.E. Vokes, J. Waldron, K.D. Wernecke, J. Widder, B. Zackrisson

Publikováno v: MACH-NC Collaborative Group 2021, ' Meta-analysis of chemotherapy in head and neck cancer (MACH-NC) : An update on 107 randomized trials and 19805 patients, on behalf of MACH-NC group ', Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology . https://doi.org/10.1016/j.radonc.2021.01.013
Radiother Oncol
Lacas, B, Carmel, A, Landais, C, Wong, S J, Licitra, L, Tobias, J S, Burtness, B, Ghi, M G, Cohen, E E W, Grau, C, Wolf, G, Hitt, R, Corvò, R, Budach, V, Kumar, S, Laskar, S G, Mazeron, J J, Zhong, L P, Dobrowsky, W, Ghadjar, P, Fallai, C, Zakotnik, B, Sharma, A, Bensadoun, R J, Ruo Redda, M G, Racadot, S, Fountzilas, G, Brizel, D, Rovea, P, Argiris, A, Nagy, Z T, Lee, J W, Fortpied, C, Harris, J, Bourhis, J, Aupérin, A, Blanchard, P, Pignon, J P & MACH-NC Collaborative Group 2021, ' Meta-analysis of chemotherapy in head and neck cancer (MACH-NC) : An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group ', Radiotherapy and Oncology, vol. 156, pp. 281-293 . https://doi.org/10.1016/j.radonc.2021.01.013
Radiotherapy and Oncology, 156, 281-293. ELSEVIER IRELAND LTD

Background and purposeThe Meta-Analysis of Chemotherapy in squamous cell Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) improved overall survival (OS) in patients without distant metastasis. We report the updated resul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de5e870d2a043397c2d56fbe66f9f3e
http://hdl.handle.net/2318/1786784

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Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis

Autor: Brian O'Sullivan, Everett E. Vokes, J. Bernier, J. Vermorken, Jean-Jacques Mazeron, J.W. Lee, J. Simes, Carlo Fallai, P. Olmi, Cai Grau, K.H. Cho, B. Lacas, J.J. Cruz Hernandez, P. Graff-Cailleaud, Branislav Jeremic, J. Overgaard, Giuseppe Sanguineti, J.H. Hay, Voichita Bar-Ad, B. Gery, H. Quon, W. Dobrowsky, B. Maciejewski, M. Nankivell, Catherine Fortpied, Y. Belkacemi, Z. Szutkowski, V. Budach, David J. Adelstein, Maria Grazia Ghi, Allan Hackshaw, A. Trotti, Vincent Grégoire, Jens Overgaard, P. Blanchard, David I. Rosenthal, B. O'Sullivan, B.G. Haffty, Ju-Whei Lee, E. Moyal, M. Alfonsi, O. Choussy, S. Kumar, Barbara Burtness, M. Cheugoua-Zanetsie, C.M.P. Viegas, V. Tseroni, E. Lartigau, H. Bartelink, Björn Zackrisson, Jean-Pierre Pignon, S. Staar, J. Waldron, J.S. Wu, A. Lopes, M.G. Ghi, Sarbani Ghosh Laskar, Lisa Licitra, K.D Wernecke, C. Grau, Y.G. Tao, J. Agarwal, Yoann Pointreau, Maurice Cheugoua-Zanetsie, M. Lotayef, G. Calais, Claire Petit, J. Moon, J.A. Langendijk, C.A. Kristensen, W. Budach, Mahesh K.B. Parmar, Mahesh K. B. Parmar, Athanassios Argiris, Benjamin Lacas, C. Sire, S. Spencer, Beth M. Beadle, C. Petit, John Simes, Michael Poulsen, Arlene A. Forastiere, Q.T. Le, Adam S. Garden, L.P. Zhong, J.J. Mazeron, H. van Tinteren, Å. Bratland, Jean Pierre Pignon, Yi Li, Jeffrey S Tobias, S.H. Moon, P. Strojan, J. Bourhis, S. Temam, A. Bacigalupo, Pedro A. Torres-Saavedra, E.E. Vokes, C.M.L. Driessen, Stéphane Temam, M.M Dominello, E. Chamorey, J. Widder, Ricardo Hitt, C. van Herpen, Séverine Racadot, M. Julieron, H. Yamazaki, Rafał Suwiński, Z. Takácsi-Nagy, A. Hansen, K. Skladowski, D. Chaukar, P. Lee, S. Hayoz, F. Lewin, Marshall R. Posner, Atul Sharma, S. Mehta, M.G. Poulsen, S. Ghosh Laskar, R. Suwinski, B. Campbell, Wojciech Michalski, Jimmy J. Caudell, Jørgen Johansen, C. Simon, C. Fortpied, R. Orecchia, Volker Budach, George Shenouda, V. Torri, Shaleen Kumar, E Haddad, P. Rovea, P. Torres-Saavedra, Juan Jesús Cruz Hernández, Lai-Ping Zhong, Quynh-Thu Le, B. Zaktonik, J.W. Denham, A. Aupérin, B. Zackrisson, Gregory T. Wolf, J.C. Horiot, C. Stromberger, Jean Bourhis, S. Chabaud, Michel Lapeyre, Eric Lartigau, S.J. Wong, George Fountzilas, P. Nilsson, David M. Brizel, M.R. Posner, L. Tripcony, René-Jean Bensadoun, C. Jones, M.G. Ruo Redda, Pierre Blanchard, D. Thomson, A. Hackshaw, B. Jeremic, G. Sanguineti, Pirus Ghadjar, A. Auperin, P. Garaud

Publikováno v: Lancet Oncology, 22, 727-736
Petit, C, Lacas, B, Pignon, J-P, Le, Q T, Grégoire, V, Grau, C, Hackshaw, A, Zackrisson, B, Parmar, M K B, Lee, J-W, Ghi, M G, Sanguineti, G, Temam, S, Cheugoua-Zanetsie, M, O'Sullivan, B, Posner, M R, Vokes, E E, Cruz Hernandez, J J, Szutkowski, Z, Lartigau, E, Budach, V, Suwiński, R, Poulsen, M, Kumar, S, Ghosh Laskar, S, Mazeron, J-J, Jeremic, B, Simes, J, Zhong, L-P, Overgaard, J, Fortpied, C, Torres-Saavedra, P, Bourhis, J, Aupérin, A, Blanchard, P & MACH-NC and MARCH Collaborative Groups 2021, ' Chemotherapy and radiotherapy in locally advanced head and neck cancer : an individual patient data network meta-analysis ', The Lancet Oncology, vol. 22, no. 5, pp. 727-736 . https://doi.org/10.1016/S1470-2045(21)00076-0
The Lancet Oncology, 22(5), 727-736. ELSEVIER SCIENCE INC
Lancet Oncology, 22, 5, pp. 727-736
Petit, C, Lacas, B, Pignon, J P, Le, Q T, Grégoire, V, Grau, C, Hackshaw, A, Zackrisson, B, Parmar, M K B, Lee, J W, Ghi, M G, Sanguineti, G, Temam, S, Cheugoua-Zanetsie, M, O'Sullivan, B, Posner, M R, Vokes, E E, Cruz Hernandez, J J, Szutkowski, Z, Lartigau, E, Budach, V, Suwiński, R, Poulsen, M, Kumar, S, Ghosh Laskar, S, Mazeron, J J, Jeremic, B, Simes, J, Zhong, L P, Overgaard, J, Fortpied, C, Torres-Saavedra, P, Bourhis, J, Aupérin, A, Blanchard, P, MACH-NC and MARCH Collaborative Groups & Johansen, J 2021, ' Chemotherapy and radiotherapy in locally advanced head and neck cancer : an individual patient data network meta-analysis ', The Lancet Oncology, vol. 22, no. 5, pp. 727-736 . https://doi.org/10.1016/S1470-2045(21)00076-0

Contains fulltext : 235407.pdf (Publisher’s version ) (Closed access) BACKGROUND: Randomised, controlled trials and meta-analyses have shown the survival benefit of concomitant chemoradiotherapy or hyperfractionated radiotherapy in the treatment of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1259a72c5e0b5c71717fac9506bddb8
http://hdl.handle.net/2066/235407

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p16, HPV, and cetuximab: What is the evidence?

Autor: Bonner, J.A. Mesia, R. Giralt, J. Psyrri, A. Keilholz, U. Rosenthal, D.I. Beier, F. Schulten, J. Vermorken, J.B.

Squamous cell carcinoma of the head and neck (SCCHN) is the sixth most common cancer worldwide. It has recently been appreciated that human papillomavirus (HPV) status (or p16 status, which is a frequently used surrogate for HPV status) is prognostic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::5447d0f0e391c55684e17105a362bddc
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3086266

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Predictors of response to subsequent chemotherapy in platinum pretreated ovarian cancer: A multivariate analysis of 704 patients

Autor: J Vermorken, M. van Glabbeke, Elizabeth Eisenhauer

Publikováno v: Annals of oncology

Summary Background The probability of response to chemotherapy following platinum based treatment in ovarian cancer has usually been related to the ‘platinum-free interval’. However, in a recent European-Canadian trial of paclitaxel, serous histo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c902b627e94907e6b571e59726e7395d
https://doi.org/10.1023/a:1008240421028

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Limitations of inhibitory activities of polyphenols on furin-mediated substrate processing

Autor: John W.M. Creemers, A J Vermorken, W.J.M. Van de Ven, Jingjing Zhu, Yali Cui, Chao Chen, Jeroen Declercq

Publikováno v: Current medicinal chemistry. 19(21)

Recently, selected polyphenols were reported to exert proprotein convertase (PC) inhibitory activities on in vitro cleavage of a fluorogenic peptide substrate and it was concluded that this anti-protease activity might be responsible for the reported

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17793a29764acb45f7599620a27cf70
https://pubmed.ncbi.nlm.nih.gov/22716122

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