Zobrazeno 1 - 10
of 149
pro vyhledávání: '"J Van der Schans"'
Autor:
Jort J van der Schans, Afroditi Katsarou, George Kladis, Citlali Bar, Max Medina Ramirez, Maria Themeli, Tuna Mutis
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 22, Iss 4, Pp 100446- (2024)
The past decades have illustrated the power of T-cell engineering in the development of new and successful cell therapies, such as chimeric antigen receptor (CAR) T-cells. Despite clinical success in hematological malignancies, it also becomes increa
Externí odkaz:
https://doaj.org/article/73a1bd5279ed41b2ad0ab131429fcf69
Autor:
Mirjam de Bruin-Hoegée, Latifa Lamriti, Jan P. Langenberg, René C. M. Olivier, Lai Fun Chau, Marcel J. van der Schans, Daan Noort, Arian C. van Asten
Publikováno v:
Analytical Methods. 15:142-153
The continuing threats of military conflicts and terrorism may involve the misuse of chemical weapons. The present study aims to use environmental samples to find evidence of the release of such agents at an incident scene. A novel approach was devel
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
In the era of highly promising novel targeted-immunotherapy strategies for multiple myeloma (MM), the first series of clinical trials with CAR T-cells targeting the plasma cell-specific B-cell maturation antigen (BCMA) have shown excellent response r
Externí odkaz:
https://doaj.org/article/098e0c6f01194abe8339df2d6b5119f7
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Tuna Mutis, Richard W.J. Groen, Maria Themeli, Niels W.C.J. van de Donk, Sonja Zweegman, Fengzhi Li, Susan E. van Hal-van Veen, Esther Drent, Anne T. Gelderloos, Renée Poels, Afroditi Katsarou, Jort J. van der Schans, Lisa C. Holthof
Table providing information on scFv sequences CARs. Figures providing data on CAR T cell phenotype, BMMSC survival, target antigen expression, cytotoxic mediator measurements, Survivin and Mcl-1 expression in MM cells, effector cell survival, and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8344fac75e21eea78a873d8ab5c0504b
https://doi.org/10.1158/1078-0432.22481549.v1
https://doi.org/10.1158/1078-0432.22481549.v1
Autor:
Tuna Mutis, Richard W.J. Groen, Maria Themeli, Niels W.C.J. van de Donk, Sonja Zweegman, Fengzhi Li, Susan E. van Hal-van Veen, Esther Drent, Anne T. Gelderloos, Renée Poels, Afroditi Katsarou, Jort J. van der Schans, Lisa C. Holthof
Purpose:The microenvironment of multiple myeloma (MM) can critically impair therapy outcome, including immunotherapies. In this context, we have earlier demonstrated that bone marrow mesenchymal stromal cells (BMMSC) protect MM cells against the lyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbbf0889b264e9e02b3f2302a196959
https://doi.org/10.1158/1078-0432.c.6530726
https://doi.org/10.1158/1078-0432.c.6530726
Publikováno v:
European Journal of Public Health. 32
India has the largest share of neonatal mortality, accounting for 21.7 per 1,000 in 2019, while the global goal is at least 12 per 1,000 by 2030. More than 20% of deliveries still occur at home in India for various reasons. Several national intervent
Autor:
Debora van der Riet-van Oeveren, A. Fidder, Maria Hemme, Daan Noort, Marcel J. van der Schans
Publikováno v:
Analytical and Bioanalytical Chemistry. 413:4023-4036
The primary aim of this study was to identify biomarkers of exposure to some so-called Schedule 1 sulfur mustard (HD) analogues, in order to facilitate and expedite their retrospective analysis in case of alleged use of such compounds. Since these HD
Autor:
Susan E. van Hal-van Veen, Anne T. Gelderloos, Maria Themeli, Fengzhi Li, Renée Poels, Tuna Mutis, Jort J. van der Schans, Sonja Zweegman, Lisa C. Holthof, Richard W.J. Groen, Afroditi Katsarou, Niels W.C.J. van de Donk, Esther Drent
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, 27(13), 3793-3803. American Association for Cancer Research Inc.
Holthof, L C, van der Schans, J J, Katsarou, A, Poels, R, Gelderloos, A T, Drent, E, van Hal-van Veen, S E, Li, F, Zweegman, S, van de Donk, N W C J, Themeli, M, Groen, R W J & Mutis, T 2021, ' Bone marrow mesenchymal stromal cells can render multiple myeloma cells resistant to cytotoxic machinery of CAR T cells through inhibition of apoptosis ', Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 27, no. 13, pp. 3793-3803 . https://doi.org/10.1158/1078-0432.CCR-20-2188
Holthof, L C, van der Schans, J J, Katsarou, A, Poels, R, Gelderloos, A T, Drent, E, van Hal-van Veen, S E, Li, F, Zweegman, S, van de Donk, N W C J, Themeli, M, Groen, R W J & Mutis, T 2021, ' Bone marrow mesenchymal stromal cells can render multiple myeloma cells resistant to cytotoxic machinery of CAR T cells through inhibition of apoptosis ', Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 27, no. 13, pp. 3793-3803 . https://doi.org/10.1158/1078-0432.CCR-20-2188
Purpose: The microenvironment of multiple myeloma (MM) can critically impair therapy outcome, including immunotherapies. In this context, we have earlier demonstrated that bone marrow mesenchymal stromal cells (BMMSC) protect MM cells against the lyt