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pro vyhledávání: '"J Vanĕcek"'
Autor:
H, Zemková, J, Vanĕcek
Publikováno v:
Neuroendocrinology. 65(4)
The effect of melatonin on the gonadotropin-releasing-hormone (GnRH)-induced oscillatory rises in intracellular calcium concentration, [Ca2+]i, was studied in cultured cells from the anterior pituitary gland of 6- to 8-day-old rats. GnRH-induced [Ca2
Electrophysiological characterization of GABAA receptors in anterior pituitary cells of newborn rats
Publikováno v:
Neuroendocrinology. 62(2)
The gamma-aminobutyric acid (GABA)-ergic communication between the CNS and the anterior pituitary gland has been documented in numerous histochemical and biochemical studies but electrophysiological studies characterizing the GABAA receptor in the an
Publikováno v:
Journal of neurochemistry. 63(2)
The membrane-bound or solubilized melatonin receptors were treated with protein-modifying agents under specific conditions and then assayed for 125I-melatonin binding in order to obtain information on amino acids present in the ligand binding domain.
Autor:
J, Vanĕcek, E, Kosar
Publikováno v:
Physiological research. 43(6)
The ontogenesis of melatonin receptors in the anterior pituitary and pars tuberalis of the Golden hamster was studied using [125I]iodomelatonin as a ligand. The affinity of the binding site to the ligand (Kd) was in the range 21 to 54 pM and it did n
Autor:
P, Ekström, J, Vanĕcek
Publikováno v:
Neuroendocrinology. 55(5)
The photosensory pineal organ of teleost fish shows a circadian rhythm in melatonin synthesis, and melatonin is known to influence a number of physiological functions. However, the target sites for melatonin are not known. We have investigated the di
Autor:
J, Vanĕcek
Publikováno v:
Physiological research. 40(1)
Melatonin transduces the effect of photoperiod on the neuroendocrine system. Synthesis of melatonin in the pineal gland is well described, but the location of its target(s) and the mechanism of its action are little known. In attempt to localize mela
Akademický článek
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Akademický článek
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Publikováno v:
Brain Research. 435:359-362
125I-Melatonin was used to localize and characterize the melatonin receptor sites in the rat hypothalamus. Autoradiography revealed that displaceable 125I-melatonin binding occurred in suprachiasmatic nuclei and median eminence only. Further studies
Autor:
J Vanĕcek
Publikováno v:
Neuroendocrinology. 48:201-203
The development of melatonin receptors in the rat pituitary and median eminence was studied using [125I]melatonin as a ligand. The specific binding was detected in pituitaries of 20-day-old fetuses already. The affinity of the receptor to the ligand