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Autor:
J V, Schloss
Publikováno v:
IDrugs : the investigational drugs journal. 1(7)
This symposium was the inspiration of Joanne Stubbe (MIT, MA, USA), who organized an impressive tribute to the career of Robert H Abeles (Brandeis University, MA, USA). Professor Abeles is an influential figures in the development of 'rational drug d
Autor:
J V, Schloss
Publikováno v:
IDrugs : the investigational drugs journal. 1(7)
This symposium was organized by Dan Flynn (Monsanto Life Sciences, USA) and Timothy M Willson (Glaxo Wellcome, USA). PPARs (peroxisome proliferator-activated receptors), are nuclear hormone receptors that govern glucose and lipid homeostasis. There a
Publikováno v:
Journal of neuroscience research. 62(4)
Derivatives of C(60) have been shown to be effective free radical scavengers. Hence, many of the biological functions of fullerene are believed to be due to their antioxidant properties. Here we present evidence to show that fullerenols, that are cag
Publikováno v:
Advances in experimental medicine and biology. 442
Cysteine sulfinic acid decarboxylase (CSAD), the rate-limiting enzyme in taurine biosynthesis, was found to be activated under conditions that favor protein phosphorylation and inactivated under conditions favoring protein dephosphorylation. Direct i
Publikováno v:
Biochemical pharmacology. 55(6)
S-Methyl N,N-diethylthiolcarbamate sulfoxide (DETC-MeSO) and sulfone (DETC-MeSO2) both inhibit rat liver low Km aldehyde dehydrogenase (ALDH2) in vitro and in vivo (Nagendra et al., Biochem Pharmacol 47: 1465-1467, 1994). DETC-MeSO has been shown to
Autor:
Lonhienne, Thierry1 t.lonhienne@uq.edu.au, Nouwens, Amanda1, Williams, Craig M.1, Fraser, James A.1, Lee, Yu‐Ting1, West, Nicholas P.1, Guddat, Luke W.1 luke.guddat@uq.edu.au
Publikováno v:
Angewandte Chemie. 3/18/2016, Vol. 128 Issue 13, p4319-4323. 5p.
Autor:
J V, Schloss
Publikováno v:
The Journal of biological chemistry. 263(9)
2-Carboxy-3-keto-D-arabinitol 1,5-bisphosphate is a tightly bound intermediate of the carboxylase reaction of ribulosebisphosphate carboxylase/oxygenase. Two stereoisomers of an analog of this intermediate, 2-carboxy-D-arabinitol 1,5-bisphosphate (2C
Autor:
J V, Schloss, D E, Van Dyk
Publikováno v:
Methods in enzymology. 166
Publikováno v:
Methods in enzymology. 166
Autor:
J V, Schloss, G H, Lorimer
Publikováno v:
The Journal of biological chemistry. 257(9)
The carboxylation of ribulosebisphosphate involves a 6-carbon reaction-intermediate, 2-carboxy-3-keto-D-arabinitol 1,5-bisphosphate. This labile intermediate, radiolabeled with 14CO2, was reduced (and thereby stabilized) with NaB[3H4]. This yielded a