Zobrazeno 1 - 10
of 54
pro vyhledávání: '"J V, Melo"'
Publikováno v:
Scandinavian Journal of Haematology. 32:417-422
The monoclonal antibody RFB1, which reacts with early haemopoietic precursors in human bone marrow and peripheral T-lymphocytes, but not with pre-B cells and mature peripheral blood and marrow B lymphocytes, was tested in blood from 60 patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb0ff95e90b42fc41f2abeb0996e8fbb
https://doi.org/10.1111/j.1600-0609.1984.tb00698.x
https://doi.org/10.1111/j.1600-0609.1984.tb00698.x
Autor:
J V Melo, Bernard Malavaud, Olivier Cuvillier, A Lauret, T Kohama, Carme Martin, E. Bonhoure, D J Barnes
Publikováno v:
Leukemia. 22:971-979
We examined the involvement of sphingosine kinase-1 (SphK1), which governs the ceramide/sphingosine-1-phosphate balance, in susceptibility to imatinib of either sensitive or resistant chronic myeloid leukemia cells. Imatinib-sensitive LAMA84-s displa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6096e73ba2f97b8f3dae87af1d3bc9
https://doi.org/10.1038/leu.2008.95
https://doi.org/10.1038/leu.2008.95
Autor:
Ahmed Iqbal, Sue Saunders, S Margerison, M Anand, Deborah B. Marin, J V Melo, T Al-Jabary, Jaspal Kaeda, John M. Goldman, Jamshid S. Khorashad, J. F. Apperley
Publikováno v:
Leukemia. 20:658-663
The expansion of a leukemia clone bearing a Bcr-Abl kinase domain mutation is associated with acquired resistance to imatinib and may also predict disease progression in patients with Philadelphia-positive chronic myeloid leukemia (CML). Here we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98fc579dd1dc5c3d76c586f7f210c9fa
https://doi.org/10.1038/sj.leu.2404137
https://doi.org/10.1038/sj.leu.2404137
Autor:
Julian Topaly, Marlon R. Veldwijk, M Schad, Anna Jauch, J V Melo, Aleksandar Radujkovic, Beate Schultheis, Stephanie Laufs, Stefan Fruehauf, W. J. Zeller
Publikováno v:
Leukemia. 19:1198-1206
Overexpression of BCR-ABL and P-glycoprotein (Pgp) are two of the known mechanisms of imatinib resistance. As combination therapy may allow to overcome drug resistance, we investigated the effect of combination treatment with imatinib and 17-allylami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60624c0656d4700bd1bdc3ecc3bceed0
https://doi.org/10.1038/sj.leu.2403764
https://doi.org/10.1038/sj.leu.2403764
Autor:
Darren R. Veach, D J Barnes, William Bornmann, J. M. Goldman, J V Melo, Alex J. Tipping, Francois-Xavier Mahon, B M Clarkson, S Baluch
Publikováno v:
Leukemia. 18:1352-1356
Monotherapy of chronic myeloid leukemia (CML) with imatinib mesylate has been cast into shadow by the evolution of clinical resistance during therapy. Resistance to imatinib can arise by multiple mechanisms including amplification or mutation of Bcr-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0eea3656d2cbd74638abd47cd8a088e
https://doi.org/10.1038/sj.leu.2403416
https://doi.org/10.1038/sj.leu.2403416
Publikováno v:
Proceedings of 10th World Congress on Computational Mechanics.
The techniques used in old buildings, as in suspension bridges, improved in the course of time, generating curved structures that minimize materials and maximize strength. Among the curves used there is the catenary curve, which is an excellent way o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbc8ca0de6d3e5361bcc32c504f0f234
https://doi.org/10.5151/meceng-wccm2012-18637
https://doi.org/10.5151/meceng-wccm2012-18637
Publikováno v:
Leukemia. 11:195-201
We have sought the presence of rearrangements of the immunoglobulin heavy chain gene locus in 13 patients with chronic myeloid leukemia (CML) in lymphoid blastic transformation (L-BT) using the polymerase chain reaction (PCR). The lymphoid nature of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af39bee93848016decb22f2d0ba2dce3
https://doi.org/10.1038/sj.leu.2400543
https://doi.org/10.1038/sj.leu.2400543
Autor:
Ute Berger, J. V. Melo, Nicholas C.P. Cross, Ruediger Hehlmann, R. B. Arlinghaus, C. Sick, H. Skladny, J. Q. Guo, Andreas Reiter, J. M. Goldman, Andreas Hochhaus
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
A novel variant of the chimeric BCR-ABL mRNA transcript was detected in a patient with Philadelphia chromosome-negative (Ph-) chronic myelogenous leukemia (CML) by multiplex reverse-transcription polymerase chain reaction (RT-PCR). Sequence analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::845599d37649a3da49e9a59fe428c479
https://doi.org/10.1182/blood.v88.6.2236.bloodjournal8862236
https://doi.org/10.1182/blood.v88.6.2236.bloodjournal8862236
Publikováno v:
Blood. 81:158-165
Although the BCR-ABL hybrid gene on chromosome 22q-plays a pivotal role in the pathogenesis of chronic myeloid leukemia (CML), little is known of the reciprocal chimeric gene, ABL-BCR, formed on chromosome 9q+. By reverse transcription/polymerase cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd77b10901959e0227b55876eb5801d
https://doi.org/10.1182/blood.v81.1.158.158
https://doi.org/10.1182/blood.v81.1.158.158
Publikováno v:
Leukemia. 13:1894-1896
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6079b0da3b0161de774fb2838626087f
https://doi.org/10.1038/sj.leu.2401588
https://doi.org/10.1038/sj.leu.2401588