Collagen remodelling by airway smooth muscle is resistant to steroids and β₂-agonists

Autor: J E, Bourke, X, Li, S R, Foster, E, Wee, H, Dagher, J, Ziogas, T, Harris, J V, Bonacci, A G, Stewart

Publikováno v: The European respiratory journal. 37(1)

Bi-directional interactions between airway smooth muscle (ASM) and the altered extracellular matrix (ECM) may influence airway wall remodelling and ASM function in asthma. We have investigated the capacity of cultured human ASM to reorganise the stru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a7ab131ace37a9cd40fe2d994d0a6d3
https://pubmed.ncbi.nlm.nih.gov/20595143

Stiffness Mediated-Mechanosensation of Airway Smooth Muscle Cells on Linear Stiffness Gradient Hydrogels.

Autor: Tan YH; School of Human Sciences, The University of Western Australia, Perth, WA, 6009, Australia., Wang KCW; School of Human Sciences, The University of Western Australia, Perth, WA, 6009, Australia.; Telethon Kids Institute, The University of Western Australia, Nedlands, WA, 6009, Australia., Chin IL; School of Human Sciences, The University of Western Australia, Perth, WA, 6009, Australia., Sanderson RW; BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Perth, WA, 6009, Australia.; Department of Electrical, Electronic & Computer Engineering, School of Engineering, The University of Western Australia, Perth, WA, 6009, Australia., Li J; BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Perth, WA, 6009, Australia.; Department of Electrical, Electronic & Computer Engineering, School of Engineering, The University of Western Australia, Perth, WA, 6009, Australia., Kennedy BF; BRITElab, Harry Perkins Institute of Medical Research, QEII Medical Centre, Nedlands and Centre for Medical Research, The University of Western Australia, Perth, WA, 6009, Australia.; Department of Electrical, Electronic & Computer Engineering, School of Engineering, The University of Western Australia, Perth, WA, 6009, Australia.; Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University in Toruń, Grudziadzka 5, Torun, 87-100, Poland., Noble PB; School of Human Sciences, The University of Western Australia, Perth, WA, 6009, Australia., Choi YS; School of Human Sciences, The University of Western Australia, Perth, WA, 6009, Australia.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2024 Jul; Vol. 13 (18), pp. e2304254. Date of Electronic Publication: 2024 Apr 15.

Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma.

Autor: Guidi, Riccardo, Xu, Daqi, Choy, David F., Ramalingam, Thirumalai R., Lee, Wyne P., Modrusan, Zora, Liang, Yuxin, Marsters, Scot, Ashkenazi, Avi, Huynh, Alison, Mills, Jessica, Flanagan, Sean, Hambro, Shannon, Nunez, Victor, Leong, Laurie, Cook, Ashley, Tran, Tiffany Hao, Austin, Cary D., Cao, Yi, Clarke, Christine

Publikováno v: Science Translational Medicine; 4/20/2022, Vol. 14 Issue 641, p1-17, 17p

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases.

Autor: Kulkarni, Ajit A.^1,2, Woeller, Collynn F.^2,3, Thatcher, Thomas H.^1,2, Ramon, Sesquile^2,4, Phipps, Richard P.^2,3,4, Sime, Patricia J.^1,2,3,4,5 patricia_sime@urmc.rochester.edu

Publikováno v: PPAR Research. 2012, Special section p1-13. 13p. 1 Diagram, 1 Graph.

The Role of PPARs in Lung Fibrosis.

Autor: Lakatos, Heather F.^1,2, Thatcher, Thomas H.^2,3, Kottmann, R. Matthew^2,3, Garcia, Tatiana M.^2,4, Phipps, Richard P.^1,2,4, Sime, Patricia J.^1,2,3

Publikováno v: PPAR Research. 2007 Special Issue 2, p1-10. 10p. 2 Diagrams, 1 Chart.