Zobrazeno 1 - 10
of 66
pro vyhledávání: '"J Upward"'
Autor:
B D, Zussman, L J, Benincosa, D M, Webber, D J, Clark, H, Cowley, J, Kelly, R D, Murdoch, J, Upward, P, Wyld, A, Port, H, Fuder
Publikováno v:
Journal of Clinical Pharmacology. 41:950-958
The oral pharmacokinetics of cilomilast (Ariflo) were investigated in five separate studies in healthy volunteers. Cilomilast was rapidly absorbed, and pharmacokinetics were dose proportional after single and repeat dosing. The elimination half-life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5a460d2258105132c97ef93da1e507
https://doi.org/10.1177/00912700122010924
https://doi.org/10.1177/00912700122010924
Autor:
J. Upward, O. B. Eden, Alan W. Craft, R. W. F. Campbell, D. M. Pierce, L. Price, Peter J. Shaw, R. Murdoch
Publikováno v:
Medical and Pediatric Oncology. 25:28-32
The safety and efficacy of the new 5HT-3 antagonist granisetron as an antiemetic in children with cancer was evaluated in 40 children at a single dose of 40 μg/kg. No adverse affects attributable to the granisetron were noted. The overall major and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8842e50aeeab591d22d3f59e2e6eea79
https://doi.org/10.1002/mpo.2950250107
https://doi.org/10.1002/mpo.2950250107
Publikováno v:
International journal of clinical pharmacology and therapeutics. 34(9)
Pranlukast is a novel LTD4 antagonist under development for the treatment of asthma. To assess the effect of age, the pharmacokinetics of pranlukast were studied in healthy young (9 females, 10 males, mean 30 years) and elderly subjects (9 per sex, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::816d244b05ca39b98edf0e4ee8cec9e5
https://pubmed.ncbi.nlm.nih.gov/8880285
https://pubmed.ncbi.nlm.nih.gov/8880285
Publikováno v:
European Journal of Clinical Pharmacology. 48
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af558c284546dba8107eb293a0e75aec
https://doi.org/10.1007/bf00194344
https://doi.org/10.1007/bf00194344
Publikováno v:
European Journal of Clinical Pharmacology. 46
The pharmacokinetics and tolerance of granisetron, a novel 5HT3-receptor antagonist which is under development as an anti-emetic agent have been studied after administration of single 30 min intravenous infusions to three groups of 8 healthy male sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7582d831ab0238fe282961bd8509ad4
https://doi.org/10.1007/bf00199881
https://doi.org/10.1007/bf00199881
Autor:
J, Upward
Publikováno v:
The Health service journal. 104(5385)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fc6d15be0dde0616d20864e1586d5b4
https://pubmed.ncbi.nlm.nih.gov/10164888
https://pubmed.ncbi.nlm.nih.gov/10164888
Autor:
A E, Hunter, H G, Prentice, K, Pothecary, A, Coumar, C, Collis, J, Upward, R, Murdoch, L, Gandhi, M, Hamon, M, Butler
Publikováno v:
Bone marrow transplantation. 7(6)
The antiemetic efficacy of granisetron was tested in an open trial in patients undergoing highly emetogenic treatment by single fraction total body irradiation. Thirty-two consecutive patients were entered. Results were both patient- and observer-rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4f1130ba401d9f11661f201ce4cb196
https://pubmed.ncbi.nlm.nih.gov/1651794
https://pubmed.ncbi.nlm.nih.gov/1651794
Publikováno v:
Heart. 53:598-602
One hundred and two consecutive patients with a history of chest pain or recent previous myocardial infarction underwent maximal treadmill stress testing and coronary angiography. The diastolic blood pressure response to exercise was evaluated indepe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3c994914453af50af41c2a30430940
https://doi.org/10.1136/hrt.53.6.598
https://doi.org/10.1136/hrt.53.6.598
Publikováno v:
BMJ. 290:1931-1934
The clinical relevance of reciprocal changes in the ST segment occurring at the time of acute myocardial infarction was studied prospectively in 85 consecutive uncomplicated cases. Reciprocal depression of the ST segment was defined as depression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd5a55549c6c21ed7b183a4771f98be
https://doi.org/10.1136/bmj.290.6486.1931
https://doi.org/10.1136/bmj.290.6486.1931
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