Zobrazeno 1 - 10
of 1 652
pro vyhledávání: '"J Tyrrell"'
Autor:
WD Thompson, RM Reynolds, RN Beaumont, NM Warrington, J Tyrrell, AR Wood, DM Evans, TJ McDonald, AH Hattersley, RM Freathy, DA Lawlor, MC Borges
Publikováno v:
BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Observational studies and randomized controlled trials have found evidence that higher maternal circulating cortisol levels in pregnancy are associated with lower offspring birth weight. However, it is possible that the observatio
Externí odkaz:
https://doaj.org/article/184b224809554cf29e490e6fb1d795b3
Autor:
Vanessa Meier-Stephenson, Michael T. Hawkes, Catherine Burton, Ainslie Calcutt, Chris Davis, Jessica Dooley, Michael Good, Michael Houghton, Eloise Keeffe, Kelly Kim, Ailin Lepletier, Conar O’Neil, Ijeoma Ogbuehi, Victoria Ozberk, Manisha Pandey, Simone Reynolds, Avi Seth, William Stokes, Alena Tse-Chang, Ben Tyrrell, D. Lorne Tyrrell, Gregory J. Tyrrell, Maryna Yaskina
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-16 (2024)
Abstract Background Group A streptococci (Strep A) orStreptococcus pyogenes is a major human pathogen causing an estimated 500,000 deaths worldwide each year. Disease can range from mild pharyngitis to more severe infections, such as necrotizing fasc
Externí odkaz:
https://doaj.org/article/3b507af6859c43d3b742a62462d6dfde
Autor:
Deanna M. Santer, Daniel Li, Yanal Ghosheh, Muhammad Atif Zahoor, Dhanvi Prajapati, Bettina E. Hansen, D. Lorne J. Tyrrell, Jordan J. Feld, Adam J. Gehring
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The interferon response is a critical component response to SARS-CoV-2 infection and prior studies have established a role for the administration of PEGylated interferon-lambda1 and its impact on viral clearance. Here the authors show that PEGylated
Externí odkaz:
https://doaj.org/article/76aeb35452c84e428bbee3f01d975611
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 8, Pp 1615-1623 (2022)
The relationship between increased short-term mortality rates after invasive pneumococcal disease (IPD) has been frequently studied. However, the relationship between IPD and long-term mortality rates is unknown. IPD patients in Alberta, Canada, had
Externí odkaz:
https://doaj.org/article/c40093b8d8b3421e9c2a2ed2681364f9
Autor:
Ruwandi M. Kariyawasam, Danielle A. Julien, Dana C. Jelinski, Samantha L. Larose, Elissa Rennert-May, John M. Conly, Tanis C. Dingle, Justin Z. Chen, Gregory J. Tyrrell, Paul E. Ronksley, Herman W. Barkema
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 11, Iss 1, Pp 1-18 (2022)
Abstract Background Pneumonia from SARS-CoV-2 is difficult to distinguish from other viral and bacterial etiologies. Broad-spectrum antimicrobials are frequently prescribed to patients hospitalized with COVID-19 which potentially acts as a catalyst f
Externí odkaz:
https://doaj.org/article/dc4ec0f77a984dcdbceefc9ab80f2f07
Autor:
Mariya Misheva, Konstantinos Kotzamanis, Luke C. Davies, Victoria J. Tyrrell, Patricia R. S. Rodrigues, Gloria A. Benavides, Christine Hinz, Robert C. Murphy, Paul Kennedy, Philip R. Taylor, Marcela Rosas, Simon A. Jones, James E. McLaren, Sumukh Deshpande, Robert Andrews, Nils Helge Schebb, Magdalena A. Czubala, Mark Gurney, Maceler Aldrovandi, Sven W. Meckelmann, Peter Ghazal, Victor Darley-Usmar, Daniel A. White, Valerie B. O’Donnell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Oxylipins are lipid mediators generated during infection for regulating inflammatory responses, but how they are removed is not completely clear. Here the authors show that cellular oxylipin removal is linked to mitochondria β-oxidation by CPT1, a m
Externí odkaz:
https://doaj.org/article/a3d11671abcf4409a6bdffc0da87c0f3
Autor:
Grace Huang, Irene Martin, Raymond S Tsang, Walter H Demczuk, Gregory J Tyrrell, Y Anita Li, Catherine Dickson, Francesca Reyes-Domingo, Susan G Squires
Publikováno v:
Canada Communicable Disease Report, Vol 47, Iss 11, Pp 545-554 (2021)
Contexte : Le programme de surveillance circumpolaire internationale assure la surveillance de cinq maladies bactériennes invasives : les pneumococcies invasives, les infections invasives à streptocoque du groupe A, l’Haemophilus influenzae, les
Externí odkaz:
https://doaj.org/article/3d8b409df10f4f418bf17b3a0d552150
Autor:
Grace Huang, Irene Martin, Raymond S Tsang, Walter H Demczuk, Gregory J Tyrrell, Y Anita Li, Catherine Dickson, Francesca Reyes-Domingo, Susan G Squires
Publikováno v:
Canada Communicable Disease Report, Vol 47, Iss 11, Pp 491-499 (2021)
Background: The International Circumpolar Surveillance (ICS) program conducts surveillance on five invasive bacterial diseases: pneumococcal disease (IPD), group A streptococcus (iGAS), Haemophilus influenzae (Hi), meningococcal disease (IMD) and gro
Externí odkaz:
https://doaj.org/article/0a220d01db1841a28df8f0152c179662
Autor:
Maral Aminpour, Williams Ernesto Miranda Delgado, Soren Wacker, Sergey Noskov, Michael Houghton, D. Lorne J. Tyrrell, Jack A. Tuszynski
Publikováno v:
BMC Pharmacology and Toxicology, Vol 22, Iss 1, Pp 1-20 (2021)
Abstract Background The emergence and rapid spread of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) in thelate 2019 has caused a devastating global pandemic of the severe pneumonia-like disease coronavirus disease 2019 (COVID-19). Alth
Externí odkaz:
https://doaj.org/article/950a279162d149fe991a7933805bb00a
Autor:
Alisa A. Omelchenko, Hua Bai, Emma C. Spina, Jordan J. Tyrrell, Jackson T. Wilbourne, Lina Ni
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Animals are continuously confronted with different rates of temperature variation. The mechanism underlying how temperature-sensing systems detect and respond to fast and slow temperature changes is not fully understood in fly larvae. Here, we applie
Externí odkaz:
https://doaj.org/article/f0044de5ba4149729503b639c0d54339