Zobrazeno 1 - 10
of 90
pro vyhledávání: '"J Truax"'
Publikováno v:
Geophysical Research Letters, Vol 51, Iss 9, Pp n/a-n/a (2024)
Abstract Increasing snow accumulation over the Antarctic Ice Sheet may mitigate future sea level rise. However, current estimates of mitigation potential are poorly constrained due to limited records of past variability. We present an annually resolv
Externí odkaz:
https://doaj.org/article/5e4696f69b3e49bea571e83cd159e8e3
Autor:
Olivia J. Truax, Bette L. Otto-Bliesner, Esther C. Brady, Craig L. Stevens, Gary S. Wilson, Christina R. Riesselman
Publikováno v:
Geosciences, Vol 12, Iss 8, p 299 (2022)
Improved understanding of the drivers of climate variability, particularly over the last millennium, and its influence on Antarctic ice melt have important implications for projecting ice sheet resilience in a changing climate. Here, we investigated
Externí odkaz:
https://doaj.org/article/bf1fc3a2c82841a99223c66052325c95
Autor:
Ola El Atab, Rabih Darwiche, Nathanyal J. Truax, Roger Schneiter, Kenneth G. Hull, Daniel Romo, Oluwatoyin A. Asojo
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
During their infective stages, hookworms release excretory-secretory (E-S) products, small molecules, and proteins to help evade and suppress the host's immune system. Small molecules found in E-S products of mammalian hookworms include nematode deri
Externí odkaz:
https://doaj.org/article/2486b41387b24a07b433cc5e979a4cdf
Publikováno v:
J Am Chem Soc
A pharmacophore-directed retrosynthetic (PDR) strategy was applied to the first total synthesis of the cembranoid, rameswaralide, in order to simultaneously achieve a total synthesis while also developing a structure-activity relationship profile thr
Akademický článek
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Autor:
Nathanyal J. Truax, Daniel Romo
Publikováno v:
Nat Prod Rep
Covering: 1986 to 2020Natural products are an enduring source of chemical information useful for probing biologically relevant chemical space. Toward gathering further structure-activity relationship (SAR) information for a particular natural product
Publikováno v:
Organic Letters. 21:7394-7399
A pharmacophore-directed retrosynthesis strategy applied to rameswaralide provided simplified precursors bearing the common 5,5,6 (red) and 5,5,7 (blue) skeleton present in several cembranoid and n...
Autor:
M. Herzler, J. Abedini, D. Allen, A.M. Api, D. Germolec, J. Gordon, H.-S. Ko, J. Matheson, J. Strickland, H.-J. Thierse, K. To, J. Truax, J.T. Vanselow, N. Kleinstreuer
Publikováno v:
Toxicology Letters. 368:S65
Autor:
Deborah O. Kwansare, Kaitlynn A. Sockett, Namita D. Neerukonda, Patricia Mowery, Erin T. Pelkey, Megan M. Lafferty, Nathan R. Webster, Marissa A. McFadden, Kelsey Pierce, Brianna Hurysz, Roslyn R. Patel, Nathanyal J. Truax, Madison M. Filkorn
Publikováno v:
Bioorganicmedicinal chemistry letters. 41
Analogs of diarylpyrrolinone lead compound 1 were prepared and tested for anti-proliferative activity in U-937 cancer cells. Alterations of 1 focused on modifying the two nitrogen atoms: a) the pyrrolinone nitrogen atom was substituted with a propyl